The interaction of type 2 diabetes type 3 diabetes Alzheimer s disease and the gut microbiota

Written By Hyder Mirghani
The interaction of type 2 diabetes  type 3 diabetes  Alzheimer s disease   and the gut microbiota
  • Publsiher : GRIN Verlag
  • Release : 19 December 2017
  • ISBN : 3668596786
  • Pages : 57 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled The interaction of type 2 diabetes type 3 diabetes Alzheimer s disease and the gut microbiota written by Hyder Mirghani which was release on 19 December 2017, this book published by GRIN Verlag. Available in PDF, EPUB and Kindle Format. Book excerpt: Literature Review from the year 2017 in the subject Medicine - Internal Medicine, grade: C, , language: English, abstract: Dementia is a multifaceted syndrome with a significant public health, social, and economic burden; there are forty-four million people affected by the disease worldwide according to the most recent estimate.The number is projected to double by the year 2030 and to triple by 2050. Alzheimer's disease (AD, or type-3 diabetes mellitus) and vascular dementia are the most common forms of dementia. Lifestyle risk factors including obesity and type 2 diabetes increase the risk for the development of both vascular and nonvascular dementia in later life. Previous literature reported that people with diabetes mellitus had 70% greater risk for dementia development.Traditionally, type-2 diabetes and AD (type-3 diabetes) have been thought as independent disorders; recent literature suggests possible links that could lead to common effective modalities of treatment. Furthermore, the highly innervated pancreas shares many features with the brain at molecular levels. Metformin is recommended as the first line for the treatment of patients with type 2 diabetes mellitus due to its effectiveness, favorable effects on lipids and cardiovascular risks, and safety profile.The previous restriction of the use of metformin in patients with the moderate renal disease is loosened by the Food and Drug Organization(5,6). Thus the use of this valuable and affordable drug is expected to increase. The American Diabetes Association recommended the periodic measurement of vitamin B12 and supplementation as needed to reflect the recent evidence showing the association of long-term use of metformin and B12 deficiency.Although the role of vitamin B12 deficiency in the development of dementia is well-established, the role of metformin in B12 deficiency and dementia remain to be elucidated. Insulin resistance is considered as a primary factor for the association of diabetes mellitus and dementia. However, the role of insulin sensitizer in the prevention of dementia remains unclear.Furthermore, there is an increasing concern about the role of metformin in cognitive disorders.Thus we conducted this narrative review, in this study we reviewed the literature to assess the interaction of Alzheimer's disease, the gut, and its microbiome, and to assess the role of metformin and other drugs used for type 1&2 diabetes mellitus as possible therapies for the AD. The role of microbiota and fecal transplantation on cognitive disorders was also discussed.

The interaction of type 2 diabetes type 3 diabetes Alzheimer s disease and the gut microbiota

The interaction of type 2 diabetes  type 3 diabetes  Alzheimer s disease   and the gut microbiota
  • Author : Hyder Mirghani
  • Publisher : GRIN Verlag
  • Release Date : 2017-12-19
  • Total pages : 57
  • ISBN : 3668596786
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Summary : Literature Review from the year 2017 in the subject Medicine - Internal Medicine, grade: C, , language: English, abstract: Dementia is a multifaceted syndrome with a significant public health, social, and economic burden; there are forty-four million people affected by the disease worldwide according to the most recent estimate.The number is ...

The Interaction of Type 2 Diabetes Type 3 Diabetes Alzheimer s Disease and Thegut Microbiota

The Interaction of Type 2 Diabetes  Type 3 Diabetes  Alzheimer s Disease   and Thegut Microbiota
  • Author : Hyder Mirghani
  • Publisher : Grin Publishing
  • Release Date : 2018-01-12
  • Total pages : 64
  • ISBN : 3668596786
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Summary : Literature Review from the year 2017 in the subject Medicine - Internal Medicine, grade: C, language: English, abstract: Dementia is a multifaceted syndrome with a significant public health, social, and economic burden; there are forty-four million people affected by the disease worldwide according to the most recent estimate.The number is ...

Type 2 Diabetes and Dementia

Type 2 Diabetes and Dementia
  • Author : Velandai Srikanth,Zoe Arvanitakis
  • Publisher : Academic Press
  • Release Date : 2018-02-09
  • Total pages : 320
  • ISBN : 3668596786
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Summary : Type 2 Diabetes and Dementia details the relationship between diabetes, dementia and the future of medicine and therapeutics. Chapters range from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and the application of therapeutics. The book reflects the translational aspects of the current science ...

A Study of Mechanisms Linking Type 2 Diabetes Mellitus and Dementia

A Study of Mechanisms Linking Type 2 Diabetes Mellitus and Dementia
  • Author : Christopher Moran
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 522
  • ISBN : 3668596786
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Summary : Background: Dementia is highly prevalent in older age, accounts for a significant proportion of age-related disability, and is one of the most expensive disorders affecting older Australians. T2DM affects about 85% of all people with diabetes and occurs more commonly in older age. T2DM increases the risk of vascular ...

Diabetes and the Brain

Diabetes and the Brain
  • Author : Geert Jan Biessels,Jose A. Luchsinger
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-09-18
  • Total pages : 474
  • ISBN : 3668596786
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Summary : Diabetes, particularly type 2, has become increasingly more common around the world. Consequently, the effect of diabetes on the brain has achieved enormous public health importance. A surge in pre-clinical and clinical research on topics ranging from management of hyperglycemia in acute stroke to disturbances in insulin signaling in Alzheimer’s ...

The New Threat of Type 3 Diabetes

The New Threat of Type 3 Diabetes
  • Author : Alan D. Raguso,Maria Lizotte RN BSN CDE
  • Publisher : iUniverse
  • Release Date : 2018-11-08
  • Total pages : 130
  • ISBN : 3668596786
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Summary : The American diet is typically high in sugar consumption and extremely acidic. This lifestyle leads to insulin resistance, inflammation, diabetes, high blood pressure, risk for heart attack or stroke, and possibly dementia and Alzheimer’s disease. In The New Threat of Type 3 Diabetes, authors Alan D. Raguso and Maria Lizotte ...

Diabetes and Aging An Issue of Clinics in Geriatric Medicine

Diabetes and Aging  An Issue of Clinics in Geriatric Medicine
  • Author : Elsa S. Strotmeyer
  • Publisher : Elsevier Health Sciences
  • Release Date : 2014-12-26
  • Total pages : 177
  • ISBN : 3668596786
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Summary : This issue of Clinics in Geriatric Medicine, guest edited by Dr. Elsa S. Strotmeyer, is devoted to Medical Complications of Diabetes in Older Adults. Articles in this issue include: Glucose Dysregulation: Pathophysiology and Prevention; Diabetic Medications and Polypharmacy; Physical Function and Disability; Diabetes and Osteoarthritis; Adiposity, Muscle Mass, and Diabetes; ...

The New Threat of Type 3 Diabetes

The New Threat of Type 3 Diabetes
  • Author : Alan D. Raguso,Maria Lizotte Rn Bsn Cde
  • Publisher : Unknown
  • Release Date : 2018-11-08
  • Total pages : 130
  • ISBN : 3668596786
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Summary : The American diet is typically high in sugar consumption and extremely acidic. This lifestyle leads to insulin resistance, inflammation, diabetes, high blood pressure, risk for heart attack or stroke, and possibly dementia and Alzheimer's disease. In The New Threat of Type 3 Diabetes, authors Alan D. Raguso and Maria Lizotte offer ...

Life at Home for People with a Dementia

Life at Home for People with a Dementia
  • Author : Ruth Bartlett,Tula Brannelly
  • Publisher : Routledge
  • Release Date : 2018-06-14
  • Total pages : 142
  • ISBN : 3668596786
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Summary : Life at Home for People with a Dementia provides an evidence-based and readable account of improving life at home for people with a dementia and their families. There are estimated to be 47 million people with a dementia worldwide, the majority of whom will live, or want to live, in their ...

The Diabetic Brain in Alzheimer s Disease How Insulin Resistance in Type 2 Diabetes and Type 3 Diabetes Triggers Your Risk for Alzheimer s and How

The Diabetic Brain in Alzheimer s Disease  How Insulin Resistance in Type 2 Diabetes and  Type 3 Diabetes  Triggers Your Risk for Alzheimer s and How
  • Author : Ralph Sanchez Mtcm
  • Publisher : Braindefend LLC
  • Release Date : 2019-08-21
  • Total pages : 122
  • ISBN : 3668596786
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Summary : The thought of living out one's life with dementia conjures up a helpless and foreboding feeling. What if it happens to me?Can I do anything to prevent it?One in ten people age 65 and older has Alzheimer's, and the prevalence of the disease jumps to three in ten after ...

Comparative Effectiveness of Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on the Risk of Dementia in Patients with Type 2 Diabetes and Hypertension

Comparative Effectiveness of Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on the Risk of Dementia in Patients with Type 2 Diabetes and Hypertension
  • Author : Hemalkumar B. Mehta
  • Publisher : Unknown
  • Release Date : 2014
  • Total pages : 212
  • ISBN : 3668596786
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Summary : Objectives: Specific aims of the study were: (1) To develop RxDx risk index to predict dementia in patients with type 2 diabetes mellitus and hypertension (2) To compare RxDx risk index with different versions of Charlson comorbidity score (CCS) and chronic disease score (CDS) to predict dementia and (3) To compare Angiotensin Converting Enzyme (...

Diabetes Mellitus

Diabetes Mellitus
  • Author : Yusaku Nakabeppu,Toshiharu Ninomiya
  • Publisher : Springer
  • Release Date : 2019-05-06
  • Total pages : 248
  • ISBN : 3668596786
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Summary : This book describes the precise mechanisms by which insulin resistance and diabetes mellitus (DM) act as risk factors for Alzheimer’s disease (AD). It opens by discussing the de novo synthesis of insulin in the brain and its functional significance with regard to glucose metabolism and maintenance of neuronal function ...

Diabetes in Old Age

Diabetes in Old Age
  • Author : Alan J. Sinclair,Trisha Dunning,Leocadio Rodríguez Mañas,Medha Munshi
  • Publisher : John Wiley & Sons
  • Release Date : 2017-02-13
  • Total pages : 576
  • ISBN : 3668596786
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Summary : This new edition of the popular and market-leading Diabetes in Old Age features up-to-date and comprehensive information about the key aspects of managing older people with diabetes, predominantly type 2 diabetes. With a strong evidence-based focus throughout, the entire range of issues surrounding diabetes and its many complications are covered, each ...

Impact of Lipid Lowering Agents on the Incidence of Dementia and Type 2 Diabetes A Population based Cohort Study in Older Mexican Americans Living in the Sacramento Area of California

Impact of Lipid Lowering Agents on the Incidence of Dementia and Type 2 Diabetes  A Population based Cohort Study in Older Mexican Americans Living in the Sacramento Area of California
  • Author : Caryn L. Cramer
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 212
  • ISBN : 3668596786
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Summary : Download or read online Impact of Lipid Lowering Agents on the Incidence of Dementia and Type 2 Diabetes A Population based Cohort Study in Older Mexican Americans Living in the Sacramento Area of California written by Caryn L. Cramer, published by which was released on 2007. Get Impact of Lipid Lowering Agents ...

Reverse Alzheimer s Disease Naturally

Reverse Alzheimer s Disease Naturally
  • Author : Michelle Honda
  • Publisher : Hatherleigh Press
  • Release Date : 2019-04-16
  • Total pages : 176
  • ISBN : 3668596786
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Summary : Breakthrough and effective natural medicine approaches to manage and treat Alzheimer's disease. More than 44 million people are affected by Alzheimer's disease worldwide. Millions of people of all ages are battling this disabling brain impairment, causing a health care crisis of epidemic proportions. Reverse Alzheimer's Disease Naturally provides a comprehensive overview ...