Membrane Transporters in Drug Discovery and Development

Written By Qing Yan
Membrane Transporters in Drug Discovery and Development
  • Publsiher : Humana
  • Release : 26 April 2010
  • ISBN : 0987654321
  • Pages : 365 pages
  • Rating : 4/5 from 21 reviews
GET THIS BOOKMembrane Transporters in Drug Discovery and Development


Read or download book entitled Membrane Transporters in Drug Discovery and Development written by Qing Yan which was release on 26 April 2010, this book published by Humana. Available in PDF, EPUB and Kindle Format. Book excerpt: This text provides practical methodologies of the ongoing research on membrane transporters, considering applications of transporter technologies in drug discovery and development.

Membrane Transporters in Drug Discovery and Development

Membrane Transporters in Drug Discovery and Development
  • Author : Qing Yan
  • Publisher : Humana
  • Release Date : 2010-04-26
  • Total pages : 365
  • ISBN : 0987654321
GET BOOK

Summary : This text provides practical methodologies of the ongoing research on membrane transporters, considering applications of transporter technologies in drug discovery and development....

Transporters in Drug Discovery and Development

Transporters in Drug Discovery and Development
  • Author : Yurong Lai
  • Publisher : Woodhead Publishing
  • Release Date : 2014-08-22
  • Total pages : 780
  • ISBN : 0987654321
GET BOOK

Summary : Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide to drug transporter families that are the most important for drug discovery and development. It covers: an overview of transporter families and organ distribution; clinical relevant drug-drug interaction; clinical relevant ...

Transporters in Drug Development

Transporters in Drug Development
  • Author : Yuichi Sugiyama,Bente Steffansen
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-09-16
  • Total pages : 317
  • ISBN : 0987654321
GET BOOK

Summary : Transporters in Drug Development examines how membrane transporters can be dealt with in academic–industrial drug discovery and pharmaceutical development as well as from a regulatory perspective. The book describes methods and examples of in vitro characterization of single transporters in the intestines, liver and kidneys as well as characterization ...

Drug Transporters

Drug Transporters
  • Author : Guofeng You,Marilyn E. Morris
  • Publisher : John Wiley & Sons
  • Release Date : 2014-07-07
  • Total pages : 528
  • ISBN : 0987654321
GET BOOK

Summary : This new edition overviews drug transporters and presents the principles of drug transport and associated techniques, featuring new chapters on multidrug and toxin extrusion proteins, placental transport, in silico approaches in drug discovery, and regulatory guidance for drug transport studies in drug development. • Describes drug transporter families, mechanisms, and clinical ...

Oral Bioavailability Assessment

Oral Bioavailability Assessment
  • Author : Ayman F. El-Kattan
  • Publisher : John Wiley & Sons
  • Release Date : 2017-06-06
  • Total pages : 448
  • ISBN : 0987654321
GET BOOK

Summary : Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability – one of the most significant hurdles in drug discovery and development. • Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability • Helps readers reduce the ...

Pharmacogenomics of Human Drug Transporters

Pharmacogenomics of Human Drug Transporters
  • Author : Toshihisa Ishikawa,Richard B. Kim,Jörg König
  • Publisher : John Wiley & Sons
  • Release Date : 2013-03-11
  • Total pages : 440
  • ISBN : 0987654321
GET BOOK

Summary : Sets the foundation for safer, more effective drugtherapies With this book as their guide, readers will discover how toapply our current understanding of the pharmacogenomics of drugtransporters to advance their own drug discovery and developmentefforts. In particular, the book explains how new findings in thefield now enable researchers to more ...

Transporters and Drug Metabolizing Enzymes in Drug Toxicity

Transporters and Drug Metabolizing Enzymes in Drug Toxicity
  • Author : Albert P. Li
  • Publisher : John Wiley & Sons
  • Release Date : 2021-07-27
  • Total pages : 528
  • ISBN : 0987654321
GET BOOK

Summary : This book provides a comprehensive and up-to-date coverage of the relationship between drug metabolism enzymes and transporters on drug toxicity, along with methods to investigate their role on adverse drug reactions. Unites both the metabolism and transporter components of drug toxicity – two aspects not normally connected and the latter often ...

Drug Transporters

Drug Transporters
  • Author : Glynis Nicholls,Kuresh Youdim
  • Publisher : Royal Society of Chemistry
  • Release Date : 2016-08-16
  • Total pages : 463
  • ISBN : 0987654321
GET BOOK

Summary : Understanding and quantifying the effects of membrane transporters within the human body is essential for modulating drug safety and drug efficacy. In this first volume on Drug Transporters, the current knowledge and techniques in the transporter sciences and their relations to drug metabolism and pharmacokinetics are comprehensively reviewed. The second ...

ADME Enabling Technologies in Drug Design and Development

ADME Enabling Technologies in Drug Design and Development
  • Author : Donglu Zhang,Sekhar Surapaneni
  • Publisher : John Wiley & Sons
  • Release Date : 2012-04-13
  • Total pages : 800
  • ISBN : 0987654321
GET BOOK

Summary : A comprehensive guide to cutting-edge tools in ADME research The last decade has seen tremendous progress in the developmentof analytical techniques such as mass spectrometry and molecularbiology tools, resulting in important advances in drug discovery,particularly in the area of absorption, distribution, metabolism,and excretion (ADME). ADME-Enabling Technologies in Drug ...

Evaluation of Drug Candidates for Preclinical Development

Evaluation of Drug Candidates for Preclinical Development
  • Author : Chao Han,Charles B. Davis,Binghe Wang
  • Publisher : John Wiley & Sons
  • Release Date : 2010-01-06
  • Total pages : 304
  • ISBN : 0987654321
GET BOOK

Summary : Emphasizes the integration of major areas of drug discovery and their importance in candidate evaluation It is believed that selecting the "right" drug candidate for development is the key to success. In the last decade, pharmaceutical R&D departments have integrated pharmacokinetics and drug metabolism, pharmaceutics, and toxicology into early ...

ABC Transporters and Multidrug Resistance

ABC Transporters and Multidrug Resistance
  • Author : Ahcène Boumendjel,Jean Boutonnat,Jacques Robert
  • Publisher : John Wiley & Sons
  • Release Date : 2009-06-17
  • Total pages : 480
  • ISBN : 0987654321
GET BOOK

Summary : A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance ATP-binding cassette transporter genes (ABC transporters) are known to play a crucial role in the development of multidrug resistance (MDR). MDR is the ability of pathologic cells, such as tumors, to withstand chemicals designed to ...

Drug Transporters Volume 2

Drug Transporters Volume 2
  • Author : Dr Glynis Nicholls ,Dr Kuresh Youdim
  • Publisher : Royal Society of Chemistry
  • Release Date : 2016-08-10
  • Total pages : 270
  • ISBN : 0987654321
GET BOOK

Summary : Understanding and quantifying the effects of membrane transporters within the human body is essential for modulating drug safety and drug efficacy. The first volume comprehensively reviewed current knowledge and techniques in the transporter sciences and their relations to drug metabolism and pharmacokinetics. In this second volume on Drug Transporters, emphasis ...

Drug Delivery

Drug Delivery
  • Author : Binghe Wang,Teruna J. Siahaan,Richard A. Soltero
  • Publisher : John Wiley & Sons
  • Release Date : 2005-04-29
  • Total pages : 464
  • ISBN : 0987654321
GET BOOK

Summary : An indispensable tool for those working at the front lines of new drug development Written for busy professionals at the forefront of new drug development, Drug Delivery gets readers quickly up to speed on both the principles and latest applications in the increasingly important field of drug delivery. Recent developments ...

Mass Spectrometry in Drug Metabolism and Disposition

Mass Spectrometry in Drug Metabolism and Disposition
  • Author : Mike S. Lee,Mingshe Zhu
  • Publisher : John Wiley & Sons
  • Release Date : 2011-03-16
  • Total pages : 800
  • ISBN : 0987654321
GET BOOK

Summary : This book examines the background, industrial context, process, analytical methodology, and technology of metabolite identification. It emphasizes the applications of metabolite identification in drug research. While primarily a textbook, the book also functions as a comprehensive reference to those in the industry. The authors have worked closely together and combine ...

Enzyme Inhibition in Drug Discovery and Development

Enzyme Inhibition in Drug Discovery and Development
  • Author : Chuang Lu,Albert P. Li
  • Publisher : John Wiley & Sons
  • Release Date : 2010-01-26
  • Total pages : 868
  • ISBN : 0987654321
GET BOOK

Summary : The science and applied approaches of enzyme inhibition in drug discovery and development Offering a unique approach that includes both the pharmacologic and pharmaco-kinetic aspects of enzyme inhibition, Enzyme Inhibition in Drug Discovery and Development examines the scientific concepts and experimental approaches related to enzyme inhibition as applied in drug ...