Thresholds of Genotoxic Carcinogens

Written By Takehiko Nohmi
Thresholds of Genotoxic Carcinogens
  • Publsiher : Academic Press
  • Release : 20 May 2016
  • ISBN : 0128018038
  • Pages : 224 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Thresholds of Genotoxic Carcinogens written by Takehiko Nohmi which was release on 20 May 2016, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Thresholds of Genotoxic Carcinogens: From Mechanisms to Regulation brings together current opinion and research activities from Japan, the US, and Europe on the subject of genotoxic thresholds. In regulation, it is an adage that genotoxic carcinogens have no thresholds for action, and that they impose cancer risk on humans even at very low levels. This policy is frequently called into question as humans possess a number of defense mechanisms including detoxication, DNA repair, and apoptosis, meaning there is a threshold at which these genotoxic carcinogens take action. The book examines these potential thresholds, describing the potential cancer risks of daily low-level exposure, the mechanisms involved (such as DNA repair, detoxication, translesion DNA synthesis), chemical and statistical methods of analysis, and the ways in which these may be utilized to inform policy. Thresholds of Genotoxic Carcinogens: From Mechanisms to Regulation is an essential reference for any professional researchers in genetic toxicology and those involved in toxicological regulation. Unites an international team of experts to provide a balanced overview of the current opinion on thresholds of genotoxic carcinogens Provides all the information readers need to determine a safe threshold for potential genotoxic carcinogens Includes information on the mechanisms of genotoxic carcinogens and how these can inform regulation Serves as an essential reference for any professional researchers in genetic toxicology and those involved in toxicological regulation

Thresholds of Genotoxic Carcinogens

Thresholds of Genotoxic Carcinogens
  • Author : Takehiko Nohmi,Shoji Fukushima
  • Publisher : Academic Press
  • Release Date : 2016-05-20
  • Total pages : 224
  • ISBN : 0128018038
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Summary : Thresholds of Genotoxic Carcinogens: From Mechanisms to Regulation brings together current opinion and research activities from Japan, the US, and Europe on the subject of genotoxic thresholds. In regulation, it is an adage that genotoxic carcinogens have no thresholds for action, and that they impose cancer risk on humans even ...

Encyclopedia of Quantitative Risk Analysis and Assessment R Z Index

Encyclopedia of Quantitative Risk Analysis and Assessment  R Z  Index
  • Author : Edward L. Melnick,Brian Everitt
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 1954
  • ISBN : 0128018038
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Summary : Download or read online Encyclopedia of Quantitative Risk Analysis and Assessment R Z Index written by Edward L. Melnick,Brian Everitt, published by which was released on 2008. Get Encyclopedia of Quantitative Risk Analysis and Assessment R Z Index Books now! Available in PDF, ePub and Kindle....

The Cellular Response to the Genotoxic Insult

The Cellular Response to the Genotoxic Insult
  • Author : Helmut Greim,Richard Albertini
  • Publisher : Royal Society of Chemistry
  • Release Date : 2015-11-09
  • Total pages : 212
  • ISBN : 0128018038
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Summary : Genotoxic carcinogens can lead to DNA mutations with the potential to cause cancer. Typically, a series of mutation events are needed before malignancy occurs so a single, small exposure may not result in disease. Also, cells have an armoury of defence mechanisms which, to a degree, counter the effects of ...

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Toxicology and Ecotoxicology in Chemical Safety Assessment
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  • Publisher : CRC PressI Llc
  • Release Date : 2005
  • Total pages : 157
  • ISBN : 0128018038
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Summary : The use of chemicals in any workplace in the developed world is governed by stringent health, safety and environmental legislation, and companies spend significant amounts of time and money assessing the risks associated with the handling and use of chemicals. In practice, those risk assessments are generally carried out by ...

Hazards in the Chemical Laboratory

Hazards in the Chemical Laboratory
  • Author : S. G. Luxon
  • Publisher : CRC Press
  • Release Date : 1992
  • Total pages : 675
  • ISBN : 0128018038
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Summary : This is a revised and updated edition of a handbook of safety practices and measures for laboratories handling dangerous chemicals. It covers recent changes in legislation, precautionary safety methods, new regulations and toxicity assessments....

Annual Report

Annual Report
  • Author : Ontario. Advisory Council on Occupational Health and Occupational Safety
  • Publisher : Unknown
  • Release Date : 1982
  • Total pages : 212
  • ISBN : 0128018038
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Summary : Download or read online Annual Report written by Ontario. Advisory Council on Occupational Health and Occupational Safety, published by which was released on 1982. Get Annual Report Books now! Available in PDF, ePub and Kindle....

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A Season of Spoils
  • Author : Jonathan Lash,Katherine Gillman,David Sheridan
  • Publisher : Pantheon
  • Release Date : 1984
  • Total pages : 385
  • ISBN : 0128018038
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Summary : Download or read online A Season of Spoils written by Jonathan Lash,Katherine Gillman,David Sheridan, published by Pantheon which was released on 1984. Get A Season of Spoils Books now! Available in PDF, ePub and Kindle....

Food in Europe Food consumption and health

Food in Europe  Food consumption and health
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1997
  • Total pages : 212
  • ISBN : 0128018038
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Summary : Download or read online Food in Europe Food consumption and health written by , published by which was released on 1997. Get Food in Europe Food consumption and health Books now! Available in PDF, ePub and Kindle....

From Mice to Men

From Mice to Men
  • Author : American Council on Science and Health
  • Publisher : Unknown
  • Release Date : 1990
  • Total pages : 57
  • ISBN : 0128018038
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Summary : Download or read online From Mice to Men written by American Council on Science and Health, published by which was released on 1990. Get From Mice to Men Books now! Available in PDF, ePub and Kindle....

Archives of industrial hygiene toxicology

Archives of industrial hygiene   toxicology
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1994
  • Total pages : 212
  • ISBN : 0128018038
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Summary : Download or read online Archives of industrial hygiene toxicology written by , published by which was released on 1994. Get Archives of industrial hygiene toxicology Books now! Available in PDF, ePub and Kindle....

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Alimentaci  n Nutrici  n Y Agricultura
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1998
  • Total pages : 212
  • ISBN : 0128018038
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Summary : Download or read online Alimentaci n Nutrici n Y Agricultura written by , published by which was released on 1998. Get Alimentaci n Nutrici n Y Agricultura Books now! Available in PDF, ePub and Kindle....

Food Nutrition and Agriculture

Food  Nutrition and Agriculture
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1998
  • Total pages : 212
  • ISBN : 0128018038
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Summary : Download or read online Food Nutrition and Agriculture written by , published by which was released on 1998. Get Food Nutrition and Agriculture Books now! Available in PDF, ePub and Kindle....

Methods to Assess Adverse Effects of Pesticides on Non Target Organisms

Methods to Assess Adverse Effects of Pesticides on Non Target Organisms
  • Author : Scientific Group on Methodologies for the Safety Evaluation of Chemicals
  • Publisher : John Wiley & Son Limited
  • Release Date : 1992-04-30
  • Total pages : 270
  • ISBN : 0128018038
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Summary : Introduction, general conclusions and recommendations. Methods to assess exposure to pesticides: data acquisition and monitoring techniques. Methods to assess toxic effects of pesticides in humans. Methods to assess toxic effects on ecosystems. Management technologies: integrated pest management. Methods to evaluate exposures to pesticides. Role of evaluative models to assess exposure ...

Trace Substances

Trace Substances
  • Author : Delbert D. Hemphill,Cotherm,University of Missouri--Columbia. Environmental Trace Substances Research Center
  • Publisher : CRC
  • Release Date : 1991-01-01
  • Total pages : 510
  • ISBN : 0128018038
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Summary : Download or read online Trace Substances written by Delbert D. Hemphill,Cotherm,University of Missouri--Columbia. Environmental Trace Substances Research Center, published by CRC which was released on 1991-01-01. Get Trace Substances Books now! Available in PDF, ePub and Kindle....

Risk Assessment and Risk Management on Non ferrous Metals

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  • Author : George M. Gray,William G. Jeffery,Gary E. Marchant,International Council on Metals and the Environment
  • Publisher : Unknown
  • Release Date : 1997
  • Total pages : 114
  • ISBN : 0128018038
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Summary : Download or read online Risk Assessment and Risk Management on Non ferrous Metals written by George M. Gray,William G. Jeffery,Gary E. Marchant,International Council on Metals and the Environment, published by which was released on 1997. Get Risk Assessment and Risk Management on Non ferrous Metals Books now! Available ...