The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

Written By Joerg Bluemel
The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment
  • Publsiher : Academic Press
  • Release : 13 March 2015
  • ISBN : 012417146X
  • Pages : 716 pages
  • Rating : 4/5 from 21 reviews
GET THIS BOOKThe Nonhuman Primate in Nonclinical Drug Development and Safety Assessment


Read or download book entitled The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment written by Joerg Bluemel which was release on 13 March 2015, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, safety assessment of biologics and small molecules, immunotoxicology and much more, this book provides scientific and technical insights to help you safely and successfully use nonhuman primates in pharmaceutical toxicity testing. A comprehensive yet practical guide, this book is intended for new researchers or practicing toxicologists, toxicologic pathologists and pharmaceutical scientists working with nonhuman primates, as well as graduate students preparing for careers in this area. Covers important topics such as species selection, study design, experimental methodologies, animal welfare and the 3Rs (Replace, Refine and Reduce), social housing, regulatory guidelines, comparative physiology, reproductive biology, genetic polymorphisms and more Includes practical examples on techniques and methods to guide your daily practice Offers a companion website with high-quality color illustrations, reference values for safety assessment and additional practical information such as study design considerations, techniques and procedures and dosing and sampling volumes

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment
  • Author : Joerg Bluemel,Sven Korte,Emanuel Schenck,Gerhard Weinbauer
  • Publisher : Academic Press
  • Release Date : 2015-03-13
  • Total pages : 716
  • ISBN : 012417146X
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Summary : The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, ...

Challenges in Nonhuman Primate Research in the 21st Century

Challenges in Nonhuman Primate Research in the 21st Century
  • Author : Gerhard F. Weinbauer,Friedhelm Vogel
  • Publisher : Waxmann Verlag
  • Release Date : 2013
  • Total pages : 180
  • ISBN : 012417146X
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Summary : In continuation of the Covance Primate Symposium Series, the 19th Covance Primate Symposium took place in Münster on 23rd & 24th of May 2012. Altogether, 70 participants representing 43 organisations, gathered for this symposium. The 2012 Primate Symposium focussed on ?Challenges in Nonhuman Primate Research in the 21st Century?. The broad participation and the ...

Drug Discovery Toxicology

Drug Discovery Toxicology
  • Author : Yvonne Will,J. Eric McDuffie,Andrew J. Olaharski,Brandon D. Jeffy
  • Publisher : John Wiley & Sons
  • Release Date : 2016-03-22
  • Total pages : 584
  • ISBN : 012417146X
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Summary : As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. • Guides researchers as to what drug safety experiments are both practical and useful • Covers ...

Drug Safety Evaluation

Drug Safety Evaluation
  • Author : Shayne C. Gad
  • Publisher : Wiley-Interscience
  • Release Date : 2002-04-18
  • Total pages : 1007
  • ISBN : 012417146X
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Summary : Covers the scientific and philosophical bases for evaluation of specific concerns, such as carcinogenicity and development toxicity....

Immunotoxicology Strategies for Pharmaceutical Safety Assessment

Immunotoxicology Strategies for Pharmaceutical Safety Assessment
  • Author : Danuta J. Herzyk,Jeanine L. Bussiere
  • Publisher : John Wiley & Sons
  • Release Date : 2008-11-21
  • Total pages : 336
  • ISBN : 012417146X
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Summary : An important reference which provides an overview of the current and recently introduced methodologies for testing the immunotoxic risks in drug candidates Helps readers understand the significance of the methods and approaches to immunotoxicology testing Aids drug scientists in industry and regulatory areas to consolidate approaches to immunotox testing Offers ...

Nonclinical Assessment of Abuse Potential for New Pharmaceuticals

Nonclinical Assessment of Abuse Potential for New Pharmaceuticals
  • Author : Carrie Markgraf,Thomas Hudzik,David Compton
  • Publisher : Academic Press
  • Release Date : 2015-07-14
  • Total pages : 320
  • ISBN : 012417146X
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Summary : Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal models used to evaluate abuse potential: physical dependence, self-administration and drug discrimination. This book also includes chapters on alternative models and examples ...

Genetic Engineering Biotechnology News

Genetic Engineering   Biotechnology News
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 212
  • ISBN : 012417146X
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Summary : Download or read online Genetic Engineering Biotechnology News written by , published by which was released on 2007. Get Genetic Engineering Biotechnology News Books now! Available in PDF, ePub and Kindle....

Impact Assessment of the Biomedical and Health Research Programme BIOMED 2

Impact Assessment of the Biomedical and Health Research Programme BIOMED 2
  • Author : European Commission. Directorate General for Research
  • Publisher : Office for Official Publications of the European Communities
  • Release Date : 2002
  • Total pages : 328
  • ISBN : 012417146X
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Summary : The Biomedical and Health Research Programme 'BIOMED2' was in operation for four years between 1994-98 with a budget of 360 million ECU. The purpose of the programme was to support the competitiveness of the European scientific research base by participating in cost-sharing research in four key areas: pharmaceuticals, biomedical technology, ...

Primate Report

Primate Report
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2005
  • Total pages : 212
  • ISBN : 012417146X
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Summary : Download or read online Primate Report written by , published by which was released on 2005. Get Primate Report Books now! Available in PDF, ePub and Kindle....

Histopathology of Preclinical Toxicity Studies

Histopathology of Preclinical Toxicity Studies
  • Author : Peter Greaves
  • Publisher : Elsevier Science Limited
  • Release Date : 1990
  • Total pages : 824
  • ISBN : 012417146X
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Summary : Histopathological assessment of tissue sections is an important componant of many preclinical studies which are conducted to support the safety and clinical development of novel therapeutic agents for use in the treatment of human diseases. The drug discovery process, aided by modern biotechnology, is now capable of generating highly potent, ...

Reviewing the Utility of Two Species in General Toxicology Related to Drug Development

Reviewing the Utility of Two Species in General Toxicology Related to Drug Development
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2021-05-15
  • Total pages : 212
  • ISBN : 012417146X
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Summary : As part of the safety assessment of new drugs, the use of two species (a rodent and a nonrodent) for regulatory toxicology studies is the typical approach taken for small molecules. For biologics, species selection is dictated by pharmacological relevance, and single species toxicology packages (typically using the nonhuman primate) ...

Developmental and Reproductive Toxicology

Developmental and Reproductive Toxicology
  • Author : Ronald D Hood
  • Publisher : CRC Press
  • Release Date : 2016-04-19
  • Total pages : 1168
  • ISBN : 012417146X
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Summary : Completely revised and updated, Developmental and Reproductive Toxicology: A Practical Approach, Second Edition draws together valuable information typically scattered throughout the literature, plus some not previously published, into one complete resource. In addition to the traditional aspects of developmental toxicity testing, the book covers evaluating and interpreting data. Originally titled ...

Environmental Chemical Exposures and Immune System Integrity

Environmental Chemical Exposures and Immune System Integrity
  • Author : Robert G. Tardiff
  • Publisher : Princeton Scientific Pub
  • Release Date : 1987
  • Total pages : 259
  • ISBN : 012417146X
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Summary : Download or read online Environmental Chemical Exposures and Immune System Integrity written by Robert G. Tardiff, published by Princeton Scientific Pub which was released on 1987. Get Environmental Chemical Exposures and Immune System Integrity Books now! Available in PDF, ePub and Kindle....

Directory of American Research and Technology

Directory of American Research and Technology
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1998
  • Total pages : 212
  • ISBN : 012417146X
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Summary : Identifies non-government facilities active in commercial research, including development of products and processes. Arrangement is alphabetic, geographic, and by concept classification....

Casarett Doull s Toxicology The Basic Science of Poisons Eighth Edition

Casarett   Doull s Toxicology  The Basic Science of Poisons  Eighth Edition
  • Author : Curtis Klaassen
  • Publisher : McGraw Hill Professional
  • Release Date : 2013-04-25
  • Total pages : 1473
  • ISBN : 012417146X
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Summary : The most trusted all-in-one overview of the biomedical and environmental aspects of toxicology--NOW more complete, up-to-date, and in full color The world's leading and most authoritative textbook on poisons has more to offer students,toxicologists, and pharmacologists than ever before. Now in full color, and thoroughly revised, the eighth edition ...