Targeting Cell Survival Pathways to Enhance Response to Chemotherapy

Written By Anonim
Targeting Cell Survival Pathways to Enhance Response to Chemotherapy
  • Publsiher : Academic Press
  • Release : 28 March 2018
  • ISBN : 0128137541
  • Pages : 308 pages
  • Rating : 4/5 from 21 reviews
GET THIS BOOKTargeting Cell Survival Pathways to Enhance Response to Chemotherapy


Read or download book entitled Targeting Cell Survival Pathways to Enhance Response to Chemotherapy written by Anonim which was release on 28 March 2018, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Targeting Cell Survival Pathways to Enhance Response to Chemotherapy encompasses recently developed molecular targeting agents and approaches that suppress cell survival signaling. Cell survival signaling attenuates the effectiveness of conventional chemotherapy and numerous mechanisms have been described, and continue to be described, which contribute to cell survival in the face of chemotherapy treatment. Key pathways leading to chemoresistance emanate from growth factor receptors, PI3K, STAT3, anti-apoptotic Bcl-2 family members, autophagy, and the DNA damage response pathway. New advances have underscored the potential of targeting each of these cell survival mechanisms to improve responsiveness to chemotherapy. This book reviews these recent advances and provides a foundational background and hints of new opportunities for basic, translational, and clinical investigators focused on improving therapeutic responses to chemotherapy. Presents cutting-edge agents and approaches with proved success in different model systems that can be translated to a different type of cancer Brings updated information to be used to propose new clinical trials investigating innovative strategies for improving responses to chemotherapy Provides mechanistic details to help guide the design of laboratory studies associated with clinical trials

Targeting Cell Survival Pathways to Enhance Response to Chemotherapy

Targeting Cell Survival Pathways to Enhance Response to Chemotherapy
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2018-03-28
  • Total pages : 308
  • ISBN : 0128137541
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Summary : Targeting Cell Survival Pathways to Enhance Response to Chemotherapy encompasses recently developed molecular targeting agents and approaches that suppress cell survival signaling. Cell survival signaling attenuates the effectiveness of conventional chemotherapy and numerous mechanisms have been described, and continue to be described, which contribute to cell survival in the face ...

New Targeting in The Reversal of Resistant Glioblastomas

New Targeting in The Reversal of Resistant Glioblastomas
  • Author : Ali Syed Arbab
  • Publisher : Academic Press
  • Release Date : 2021-03-18
  • Total pages : 202
  • ISBN : 0128137541
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Summary : New Targeting in The Reversal of Resistant Glioblastomas discusses alternative treatment strategies that not only target tumor cells but also target the tumor microenvironment, metabolic pathways and interaction of cytokines in tumor cells. The current treatment for primary and recurrent glioblastomas is failing because clinicians are not considering the effect ...

Proceedings of the National Academy of Sciences of the United States of America

Proceedings of the National Academy of Sciences of the United States of America
  • Author : National Academy of Sciences (U.S.)
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 212
  • ISBN : 0128137541
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Summary : Download or read online Proceedings of the National Academy of Sciences of the United States of America written by National Academy of Sciences (U.S.), published by which was released on 2007. Get Proceedings of the National Academy of Sciences of the United States of America Books now! Available in PDF, ...

Cancer Research

Cancer Research
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2002-08
  • Total pages : 212
  • ISBN : 0128137541
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Summary : Download or read online Cancer Research written by , published by which was released on 2002-08. Get Cancer Research Books now! Available in PDF, ePub and Kindle....

Accessing the 2 amino 5 5 disubstituted 1H imidazol 4 one Scaffold for Natural Product Synthesis and Evaluation for Checkpoint Kinase 2 Inhibition

Accessing the 2 amino 5 5 disubstituted 1H imidazol 4 one Scaffold for Natural Product Synthesis and Evaluation for Checkpoint Kinase 2 Inhibition
  • Author : Christopher David Hupp
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 418
  • ISBN : 0128137541
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Summary : Download or read online Accessing the 2 amino 5 5 disubstituted 1H imidazol 4 one Scaffold for Natural Product Synthesis and Evaluation for Checkpoint Kinase 2 Inhibition written by Christopher David Hupp, published by which was released on 2009. Get Accessing the 2 amino 5 5 disubstituted 1H imidazol 4 one Scaffold for Natural Product Synthesis and Evaluation for Checkpoint ...

Journal of Cell Science

Journal of Cell Science
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2003
  • Total pages : 212
  • ISBN : 0128137541
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Summary : Download or read online Journal of Cell Science written by , published by which was released on 2003. Get Journal of Cell Science Books now! Available in PDF, ePub and Kindle....

Anticancer Research

Anticancer Research
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 212
  • ISBN : 0128137541
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Summary : Download or read online Anticancer Research written by , published by which was released on 2009. Get Anticancer Research Books now! Available in PDF, ePub and Kindle....

European Urology Supplements

European Urology Supplements
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2002
  • Total pages : 212
  • ISBN : 0128137541
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Summary : Download or read online European Urology Supplements written by , published by which was released on 2002. Get European Urology Supplements Books now! Available in PDF, ePub and Kindle....

Journal of Experimental Biology

Journal of Experimental Biology
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2006
  • Total pages : 212
  • ISBN : 0128137541
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Summary : Download or read online Journal of Experimental Biology written by , published by which was released on 2006. Get Journal of Experimental Biology Books now! Available in PDF, ePub and Kindle....

Oncology

Oncology
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2000
  • Total pages : 212
  • ISBN : 0128137541
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Summary : Download or read online Oncology written by , published by which was released on 2000. Get Oncology Books now! Available in PDF, ePub and Kindle....

The Lymphomas

The Lymphomas
  • Author : George Peter Canellos,Thomas Andrew Lister,Bryan D. Young
  • Publisher : Saunders
  • Release Date : 2006
  • Total pages : 582
  • ISBN : 0128137541
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Summary : Edited and written by world authorities, this text encompasses all aspects of Hodgkin's disease, non-Hodgkin's lymphomas, and related disorders. Designed to be the "Bible" for both clinicians and scientists who deal with lymphoma, the book is packed with useful summary tables and abundant illustrations and translates cutting-edge discoveries into state-of-the-art ...

International Journal of Oncology

International Journal of Oncology
  • Author : Fondation nationale de la recherche scientifique (Grèce).
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 212
  • ISBN : 0128137541
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Summary : Download or read online International Journal of Oncology written by Fondation nationale de la recherche scientifique (Grèce)., published by which was released on 2009. Get International Journal of Oncology Books now! Available in PDF, ePub and Kindle....

Therapeutic Oligonucleotides

Therapeutic Oligonucleotides
  • Author : Yoon S. Cho-Chung,Alan M. Gewirtz,Cy A. Stein
  • Publisher : Unknown
  • Release Date : 2005
  • Total pages : 266
  • ISBN : 0128137541
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Summary : Explores the potential for the development of therapeutic oligonucleotides into clinical medicines and their use as basic research tools, which is the proceedings of the 7th NIH Symposium on Therapeutic Oligonucleotides. This book focuses on antisense, RNAi, triple-helix, gene repair, DNA chips, and CpG immune modulatory oligonucleotides....

Harrison s Principles of Internal Medicine 20 E Vol 1 Vol 2 ebook

Harrison s Principles of Internal Medicine 20 E  Vol 1   Vol 2   ebook
  • Author : Dennis L. Kasper,Anthony S. Fauci,Stephen L. Hauser,Dan L. Longo,J. Larry Jameson,Joseph Loscalzo
  • Publisher : McGraw Hill Professional
  • Release Date : 2018-02-06
  • Total pages : 212
  • ISBN : 0128137541
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Summary : MASTER MODERN MEDICINE! Introducing the Landmark Twentieth Edition of the Global Icon of Internal Medicine The definitive guide to internal medicine is more essential than ever with the latest in disease mechanisms, updated clinical trial results and recommended guidelines, state-of-the art radiographic images, therapeutic approaches and specific treatments, hundreds of ...

Thomas Hematopoietic Cell Transplantation

Thomas  Hematopoietic Cell Transplantation
  • Author : E. Donnall Thomas
  • Publisher : Wiley-Blackwell
  • Release Date : 2009-04-13
  • Total pages : 1718
  • ISBN : 0128137541
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Summary : Accompanying CD-ROM contains ... "full content of the book, database of figures, search function."--CD-ROM label....