Stem Cell Aging Mechanisms Consequences Rejuvenation

Written By Hartmut Geiger
Stem Cell Aging  Mechanisms  Consequences  Rejuvenation
  • Publsiher : Springer
  • Release : 06 July 2015
  • ISBN : 370911232X
  • Pages : 354 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Stem Cell Aging Mechanisms Consequences Rejuvenation written by Hartmut Geiger which was release on 06 July 2015, this book published by Springer. Available in PDF, EPUB and Kindle Format. Book excerpt: Aging of somatic stem cells reduces cell function and results in dysfunctional organs and tissues, making it an underlying cause of diseases associated with aging. It might even be the primary cause for age-associated attrition of tissue function in organs that heavily rely on stem cells for maintaining homeostasis, like the skin, blood and intestines. Understanding the molecular and cellular mechanisms involved is critical for developing approaches to attenuate stem cell aging and could pave the way for improved quality of life among the elderly. Written by highly prominent experts in the field, this book presents the current state of knowledge on these mechanisms. It offers insights into stem cell function, explains in detail the mechanisms of stem cell aging in model organisms as well as mammalian systems and describes related diseases and approaches to attenuating stem cell aging or achieving rejuvenation. The book is intended for all scientists and clinicians working with stem cells, aging mechanisms or age-related diseases.

Stem Cell Aging Mechanisms Consequences Rejuvenation

Stem Cell Aging  Mechanisms  Consequences  Rejuvenation
  • Author : Hartmut Geiger,Heinrich Jasper,Maria Carolina Florian
  • Publisher : Springer
  • Release Date : 2015-07-06
  • Total pages : 354
  • ISBN : 370911232X
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Summary : Aging of somatic stem cells reduces cell function and results in dysfunctional organs and tissues, making it an underlying cause of diseases associated with aging. It might even be the primary cause for age-associated attrition of tissue function in organs that heavily rely on stem cells for maintaining homeostasis, like ...

Stem Cells and Aging

Stem Cells and Aging
  • Author : Kursad Turksen
  • Publisher : Humana Press
  • Release Date : 2013-02-13
  • Total pages : 179
  • ISBN : 370911232X
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Summary : Over time, it has become clear that changes in stem cells do occur during aging, not only in their number but also in their relationship to their microenvironment and their functionality as reflected in changes to their metabolome. Stem Cells and Aging: Methods and Protocols brings together chapters from expert ...

Adult Stem Cells in Aging Diseases and Cancer

Adult Stem Cells in Aging  Diseases and Cancer
  • Author : K.L. Rudolph
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2014-12-22
  • Total pages : 88
  • ISBN : 370911232X
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Summary : The functionality of adult tissue stem cells from various organ systems declines during aging. This publication summarizes novel molecular mechanisms responsible for the development of aging-associated deficiencies as discussed by leading experts during the 5th Else Kröner-Fresenius Symposium. It is the first book that explicitly focuses on molecular mechanisms ...

Stem Cells and Aging

Stem Cells and Aging
  • Author : Surajit Pathak,Antara Banerjee
  • Publisher : Academic Press
  • Release Date : 2021-03-17
  • Total pages : 320
  • ISBN : 370911232X
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Summary : Stem Cells and Aging covers what is known about the effect of time and age on the basic units of life, which are the corresponding tissue-specific or adult stem cells. Even though the concept of stem cells was introduced nearly a century ago by Alexander Maximow, modern stem-cell research began ...

Antiaging Effect of Stem Cells on Aging and Stem Cell Aging

Antiaging   Effect of Stem Cells on Aging and Stem Cell Aging
  • Author : Jisook Moon
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 212
  • ISBN : 370911232X
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Summary : Aging is defined broadly as the normal progressive process, consequently leading to growing vulnerability to disease and death. A major challenge lies in dissecting the underlying mechanisms of aging with conventional experiments due to the complexity of and multicontributions to the aging process, reflecting a need for investigation into it ...

Advances in Stem Cell Aging

Advances in Stem Cell Aging
  • Author : K.L. Rudolph
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2012-09-27
  • Total pages : 134
  • ISBN : 370911232X
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Summary : Adult stem cells are present in most postnatal tissues of mammals. Tissues with high rates of cell turnover depend on the functional capacity of stem cells for lifelong maintenance of tissue homeostasis. Adult stem cells are also required for the regeneration of tissues in response to injury as in, for ...

Molecular Mechanisms of Adult Stem Cell Aging

Molecular Mechanisms of Adult Stem Cell Aging
  • Author : K.L. Rudolph
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2010-04-22
  • Total pages : 116
  • ISBN : 370911232X
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Summary : There is growing evidence that adult stem cells age. This process can result in alterations in the number and function of stem cells, leading to distinct phenotypic outcomes in different organ systems. This publication provides an outstanding overview of this emerging field.The molecular causes of stem cell aging remain ...

Telomeres and Telomerase in Aging Disease and Cancer

Telomeres and Telomerase in Aging  Disease  and Cancer
  • Author : K. Lenhard Rudolph
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-11-07
  • Total pages : 330
  • ISBN : 370911232X
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Summary : Telomere shortening represents one of the basic aspects of ageing and telomere dysfunction could contribute to the accumulation of DNA damage during ageing. This book summarizes evidence and data indicating that telomere dysfunction influences human ageing, diseases and cancer. The book describes our current knowledge on checkpoints that limit cellular ...

Mammalian Development

Mammalian Development
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1999
  • Total pages : 138
  • ISBN : 370911232X
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Summary : Download or read online Mammalian Development written by , published by which was released on 1999. Get Mammalian Development Books now! Available in PDF, ePub and Kindle....

Stem Cell Aging

Stem Cell Aging
  • Author : Primož Rožman
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 212
  • ISBN : 370911232X
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Summary : Stem cells persist throughout life, replacing cells lost to homeostatic turnover, injury, and disease. However, their functions decline with age, which contributes to degeneration and dysfunction. The molecular mechanisms involved in the aging of stem cells are the same as the ones involved in the aging of somatic cells, including ...

Centrosomal Sas 6 in Regulation of Stem Cells and Aging

Centrosomal Sas 6 in Regulation of Stem Cells and Aging
  • Author : Li Ming Gooi
  • Publisher : Unknown
  • Release Date : 2017
  • Total pages : 111
  • ISBN : 370911232X
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Summary : Download or read online Centrosomal Sas 6 in Regulation of Stem Cells and Aging written by Li Ming Gooi, published by which was released on 2017. Get Centrosomal Sas 6 in Regulation of Stem Cells and Aging Books now! Available in PDF, ePub and Kindle....

Effects of the Local Organ and Systemic Environments on Stem Cell Aging

Effects of the Local Organ and Systemic Environments on Stem Cell Aging
  • Author : Morgan Erik Carlson
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 570
  • ISBN : 370911232X
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Summary : This work uncovers mechanisms of aging within stem cell niches that are evolutionarily conserved between mice and humans, and affect both embryonic and adult stem cells. Specifically, the effects of aged muscle and systemic niches on key molecular identifiers of regenerative potential of human embryonic stem cells (hESCs) and postnatal ...

Hair Follicle Stem Cell Regeneration in Aging

Hair Follicle Stem Cell Regeneration in Aging
  • Author : Mingxing Lei,Sung-Jan Lin,Cheng Ming Chuong
  • Publisher : Frontiers Media SA
  • Release Date : 2022-01-18
  • Total pages : 212
  • ISBN : 370911232X
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Summary : Download or read online Hair Follicle Stem Cell Regeneration in Aging written by Mingxing Lei,Sung-Jan Lin,Cheng Ming Chuong, published by Frontiers Media SA which was released on 2022-01-18. Get Hair Follicle Stem Cell Regeneration in Aging Books now! Available in PDF, ePub and Kindle....

Aging Stem Cells and the Cancer Stem Cell Hypothesis

Aging  Stem Cells and the Cancer Stem Cell Hypothesis
  • Author : Dave Comstock,City University of New York. City College
  • Publisher : Unknown
  • Release Date : 2012
  • Total pages : 132
  • ISBN : 370911232X
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Summary : Download or read online Aging Stem Cells and the Cancer Stem Cell Hypothesis written by Dave Comstock,City University of New York. City College, published by which was released on 2012. Get Aging Stem Cells and the Cancer Stem Cell Hypothesis Books now! Available in PDF, ePub and Kindle....

The Anti Aging Triad

The Anti Aging Triad
  • Author : Stephen Holt
  • Publisher : AuthorHouse
  • Release Date : 2011-04-01
  • Total pages : 320
  • ISBN : 370911232X
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Summary : Th is book is a ground breaking review of the three most important scientifi c areas of anti-aging medicine. Stephen Holt MD has navigated areas of conventional and integrative medicine to produce a book that is valuable for both a layperson and biomedical experts....