Stem Cells and Aging

Written By Surajit Pathak
Stem Cells and Aging
  • Publsiher : Academic Press
  • Release : 26 March 2021
  • ISBN : 0128204133
  • Pages : 320 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Stem Cells and Aging written by Surajit Pathak which was release on 26 March 2021, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Stem Cells and Aging covers what is known about the effect of time and age on the basic units of life, which are the corresponding tissue-specific or adult stem cells. Even though the concept of stem cells was introduced nearly a century ago by Alexander Maximow, modern stem-cell research began in 1963 when James Till, Ernest McCullough and Lou Siminovitch established assays to detect hematopoietic stem cells. In fact, given the importance of the aging-associated diseases, scientists have developed a keen interest in understanding the aging process as they attempt to define the role of dysfunctional stem cells in the aging process. With an aging population worldwide, understanding these age-related stem cell changes at a basic biology level and at the level of their influences for regenerative medicine is of interest and importance. There is increasing evidence that the aging process can have much adverse effects on stem cells. In the modern era, one of the emerging fields in treating human diseases is stem cell research, as stem cells have the remarkable potential to treat a wide range of diseases. Nevertheless, understanding the molecular mechanism involved in aging and deterioration of stem cell function is crucial in developing effective new therapies for aging. Serves as an ideal reference to guide investigators toward valuable answers to the problems of our aging population Addresses the effect of time and age on human stem cells Includes chapters from contributors exploring the biology of stem cell aging around the globe

Stem Cells and Aging

Stem Cells and Aging
  • Author : Surajit Pathak,Antara Banerjee
  • Publisher : Academic Press
  • Release Date : 2021-03-26
  • Total pages : 320
  • ISBN : 0128204133
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Summary : Stem Cells and Aging covers what is known about the effect of time and age on the basic units of life, which are the corresponding tissue-specific or adult stem cells. Even though the concept of stem cells was introduced nearly a century ago by Alexander Maximow, modern stem-cell research began ...

Adult Stem Cells in Aging Diseases and Cancer

Adult Stem Cells in Aging  Diseases and Cancer
  • Author : K.L. Rudolph
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2014-12-22
  • Total pages : 88
  • ISBN : 0128204133
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Summary : The functionality of adult tissue stem cells from various organ systems declines during aging. This publication summarizes novel molecular mechanisms responsible for the development of aging-associated deficiencies as discussed by leading experts during the 5th Else Kröner-Fresenius Symposium. It is the first book that explicitly focuses on molecular mechanisms ...

Advances in Stem Cell Aging

Advances in Stem Cell Aging
  • Author : K.L. Rudolph
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2012-09-27
  • Total pages : 134
  • ISBN : 0128204133
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Summary : Adult stem cells are present in most postnatal tissues of mammals. Tissues with high rates of cell turnover depend on the functional capacity of stem cells for lifelong maintenance of tissue homeostasis. Adult stem cells are also required for the regeneration of tissues in response to injury as in, for ...

Stem Cell Aging Mechanisms Consequences Rejuvenation

Stem Cell Aging  Mechanisms  Consequences  Rejuvenation
  • Author : Hartmut Geiger,Heinrich Jasper,Maria Carolina Florian
  • Publisher : Springer
  • Release Date : 2015-07-06
  • Total pages : 354
  • ISBN : 0128204133
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Summary : Aging of somatic stem cells reduces cell function and results in dysfunctional organs and tissues, making it an underlying cause of diseases associated with aging. It might even be the primary cause for age-associated attrition of tissue function in organs that heavily rely on stem cells for maintaining homeostasis, like ...

Stem Cells and Aging

Stem Cells and Aging
  • Author : Kursad Turksen
  • Publisher : Humana Press
  • Release Date : 2013-02-13
  • Total pages : 179
  • ISBN : 0128204133
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Summary : Over time, it has become clear that changes in stem cells do occur during aging, not only in their number but also in their relationship to their microenvironment and their functionality as reflected in changes to their metabolome. Stem Cells and Aging: Methods and Protocols brings together chapters from expert ...

Molecular Mechanisms of Adult Stem Cell Aging

Molecular Mechanisms of Adult Stem Cell Aging
  • Author : K. Lenhard Rudolph
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2010
  • Total pages : 107
  • ISBN : 0128204133
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Summary : "There is growing evidence that adult stem cells age. This process can result in alterations in the number and function of stem cells, leading to distinct phenotypic outcomes in different organ systems. This publication provides an outstanding overview of this emerging field. The molecular causes of stem cell aging remain ...

Alveolar Stem Cells and Niches in Aging Injury and Evolution

Alveolar Stem Cells and Niches in Aging  Injury and Evolution
  • Author : Ahmad N. Nabhan
  • Publisher : Unknown
  • Release Date : 2019
  • Total pages : 212
  • ISBN : 0128204133
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Summary : The lung is the primary organ of respiration and the site of diseases that cause 7 million deaths annually. Although relatively understudied at the turn of the century, the field of lung stem cell biology is experiencing a renaissance due to advances in the ability to monitor and genetically mark and ...

The Immortal Cell

The Immortal Cell
  • Author : Michael D. West,H. W. Brands
  • Publisher : Doubleday Books
  • Release Date : 2003
  • Total pages : 244
  • ISBN : 0128204133
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Summary : A key player in the science of therapeutic cloning recounts the progress that has been made in reversing the aging process of cells, citing the unique qualities of stem cells and how they can be used to regenerate damaged cells and organs....

Time Cells and Aging

Time  Cells  and Aging
  • Author : Bernard Louis Strehler
  • Publisher : Unknown
  • Release Date : 1977
  • Total pages : 456
  • ISBN : 0128204133
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Summary : Times, Cells, and Aging ......

Telomeres and Telomerase in Aging Disease and Cancer

Telomeres and Telomerase in Aging  Disease  and Cancer
  • Author : K. Lenhard Rudolph
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-11-07
  • Total pages : 330
  • ISBN : 0128204133
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Summary : Telomere shortening represents one of the basic aspects of ageing and telomere dysfunction could contribute to the accumulation of DNA damage during ageing. This book summarizes evidence and data indicating that telomere dysfunction influences human ageing, diseases and cancer. The book describes our current knowledge on checkpoints that limit cellular ...

Exploring the Promise of Embryonic Stem Cell Research

Exploring the Promise of Embryonic Stem Cell Research
  • Author : United States. Congress. Senate. Special Committee on Aging
  • Publisher : Unknown
  • Release Date : 2005
  • Total pages : 57
  • ISBN : 0128204133
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Summary : Download or read online Exploring the Promise of Embryonic Stem Cell Research written by United States. Congress. Senate. Special Committee on Aging, published by which was released on 2005. Get Exploring the Promise of Embryonic Stem Cell Research Books now! Available in PDF, ePub and Kindle....

Effects of the Local Organ and Systemic Environments on Stem Cell Aging

Effects of the Local Organ and Systemic Environments on Stem Cell Aging
  • Author : Morgan Erik Carlson
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 570
  • ISBN : 0128204133
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Summary : This work uncovers mechanisms of aging within stem cell niches that are evolutionarily conserved between mice and humans, and affect both embryonic and adult stem cells. Specifically, the effects of aged muscle and systemic niches on key molecular identifiers of regenerative potential of human embryonic stem cells (hESCs) and postnatal ...

Handbook of the Biology of Aging

Handbook of the Biology of Aging
  • Author : Finchc
  • Publisher : Van Nostrand Reinhold Company
  • Release Date : 1985
  • Total pages : 1025
  • ISBN : 0128204133
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Summary : Download or read online Handbook of the Biology of Aging written by Finchc, published by Van Nostrand Reinhold Company which was released on 1985. Get Handbook of the Biology of Aging Books now! Available in PDF, ePub and Kindle....

Immunology of Aging

Immunology of Aging
  • Author : Ahmad Massoud,Nima Rezaei
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-11-29
  • Total pages : 406
  • ISBN : 0128204133
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Summary : The rapidity of scientific progress over the last few years guarantees the utility of this new collection of state-of-the-art reviews on the immunology of aging, which is the result of extensive collaboration of more than sixty of the greatest thinkers and scholars in the field, in cooperation with a number ...

Ageing Vulnerability

Ageing Vulnerability
  • Author : Gregory R. Bock,Tom Kirkwood,Jamie A. Goode,Novartis Foundation
  • Publisher : Wiley-Blackwell
  • Release Date : 2001-03-30
  • Total pages : 282
  • ISBN : 0128204133
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Summary : Ageing at individual and population levels presents one of the greatest challenges to humankind as we begin the 21st century. Throughout the world, older adults are the fasts growing population group. Ageing is associated with an increased risk for development of chronic diseases that contribute to morbidity and mortality....