Protein Folding in Silico

Written By Irena Roterman-Konieczna
Protein Folding in Silico
  • Publsiher : Elsevier
  • Release : 04 October 2012
  • ISBN : 1908818255
  • Pages : 240 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Protein Folding in Silico written by Irena Roterman-Konieczna which was release on 04 October 2012, this book published by Elsevier. Available in PDF, EPUB and Kindle Format. Book excerpt: Protein folding is a process by which a protein structure assumes its functional shape of conformation, and has been the subject of research since the publication of the first software tool for protein structure prediction. Protein folding in silico approaches this issue by introducing an ab initio model that attempts to simulate as far as possible the folding process as it takes place in vivo, and attempts to construct a mechanistic model on the basis of the predictions made. The opening chapters discuss the early stage intermediate and late stage intermediate models, followed by a discussion of structural information that affects the interpretation of the folding process. The second half of the book covers a variety of topics including ligand binding site recognition, the "fuzzy oil drop" model and its use in simulation of the polypeptide chain, and misfolded proteins. The book ends with an overview of a number of other ab initio methods for protein structure predictions and some concluding remarks. Discusses a range of ab initio models for protein structure prediction Introduces a unique model based on experimental observations Describes various methods for the quantitative assessment of the presented models from the viewpoint of information theory

Protein Folding in Silico

Protein Folding in Silico
  • Author : Irena Roterman-Konieczna
  • Publisher : Elsevier
  • Release Date : 2012-10-04
  • Total pages : 240
  • ISBN : 1908818255
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Summary : Protein folding is a process by which a protein structure assumes its functional shape of conformation, and has been the subject of research since the publication of the first software tool for protein structure prediction. Protein folding in silico approaches this issue by introducing an ab initio model that attempts ...

Protein Folding in Silico

Protein Folding in Silico
  • Author : Irena Roterman-Konieczna
  • Publisher : Woodhead Publishing
  • Release Date : 2012-10-18
  • Total pages : 240
  • ISBN : 1908818255
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Summary : Protein folding is a process by which a protein structure assumes its functional shape of conformation, and has been the subject of research since the publication of the first software tool for protein structure prediction. Protein folding in silico approaches this issue by introducing an ab initio model that attempts ...

Protein Folding in Silico

Protein Folding in Silico
  • Author : Irena Roterman-Konieczna
  • Publisher : Woodhead Publishing
  • Release Date : 2017-11-13
  • Total pages : 240
  • ISBN : 1908818255
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Summary : Protein folding is a process by which a protein structure assumes its functional shape of conformation, and has been the subject of research since the publication of the first software tool for protein structure prediction. Protein folding in silico approaches this issue by introducing an ab initio model that attempts ...

In Silico Study of Amyloid beta protein Folding Relevant to Alzheimer s Disease

In Silico Study of Amyloid  beta  protein Folding Relevant to Alzheimer s Disease
  • Author : Alfonso Ramon Lam Ng
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 204
  • ISBN : 1908818255
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Summary : Download or read online In Silico Study of Amyloid beta protein Folding Relevant to Alzheimer s Disease written by Alfonso Ramon Lam Ng, published by which was released on 2008. Get In Silico Study of Amyloid beta protein Folding Relevant to Alzheimer s Disease Books now! Available in PDF, ePub and ...

Systems Biology

Systems Biology
  • Author : Leszek Konieczny,Irena Roterman-Konieczna,Paweł Spólnik
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-10-01
  • Total pages : 204
  • ISBN : 1908818255
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Summary : The objective of this book is to present the strategies employed by living organisms on a molecular level and to help understand the basics of Systems Biology. Its content is organized in a way to meet the exponential growth in the volume of biological knowledge, and the need for a ...

Combining in Vivo and in Silico Screening for Protein Stability

Combining in Vivo and in Silico Screening for Protein Stability
  • Author : Nora Hisham Barakat
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 167
  • ISBN : 1908818255
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Summary : In the in vivo 'chimeric' screen a target protein is expressed as a fusion protein with a DNA binding domain fused at the N-terminus and a transactivation domain at the C-terminus. This three-component fusion protein acts as a functional transcription factor for a reporter gene. If the central target protein ...

Multiscale Approaches to Protein Modeling

Multiscale Approaches to Protein Modeling
  • Author : Andrzej Kolinski
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-10-13
  • Total pages : 355
  • ISBN : 1908818255
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Summary : The book gives a comprehensive review of the most advanced multiscale methods for protein structure prediction, computational studies of protein dynamics, folding mechanisms and macromolecular interactions. It approaches span a wide range of the levels of coarse-grained representations, various sampling techniques and variety of applications to biomedical and biophysical problems. ...

Combining in Vivo and in Silico Screening for Protein Stability

Combining in Vivo and in Silico Screening for Protein Stability
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 304
  • ISBN : 1908818255
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Summary : In any protein design endeavor, thermal stability is an important issue. Increasing protein stability is currently one of the main goals of the field of protein design as well as the biomedical industry. It is important for developing stable protein-based therapeutics and ultimately enhances our understanding of the principles of ...

Biomolecular Assembly in Silico Using Massively Parallel Simulations to Probe Protein and RNA Folding Dynamics

Biomolecular Assembly in Silico Using Massively Parallel Simulations to Probe Protein and RNA Folding Dynamics
  • Author : Eric J. Sorin
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 348
  • ISBN : 1908818255
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Summary : Download or read online Biomolecular Assembly in Silico Using Massively Parallel Simulations to Probe Protein and RNA Folding Dynamics written by Eric J. Sorin, published by which was released on 2007. Get Biomolecular Assembly in Silico Using Massively Parallel Simulations to Probe Protein and RNA Folding Dynamics Books now! Available in ...

Proceedings of the National Academy of Sciences of the United States of America

Proceedings of the National Academy of Sciences of the United States of America
  • Author : National Academy of Sciences (U.S.)
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 212
  • ISBN : 1908818255
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Summary : Download or read online Proceedings of the National Academy of Sciences of the United States of America written by National Academy of Sciences (U.S.), published by which was released on 2007. Get Proceedings of the National Academy of Sciences of the United States of America Books now! Available in PDF, ...

Global Representations of Protein Fold Space and Application in Structure based Inference of Protein Function

Global Representations of Protein Fold Space and Application in Structure based Inference of Protein Function
  • Author : Jingtong Hou
  • Publisher : Unknown
  • Release Date : 2004
  • Total pages : 262
  • ISBN : 1908818255
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Summary : Download or read online Global Representations of Protein Fold Space and Application in Structure based Inference of Protein Function written by Jingtong Hou, published by which was released on 2004. Get Global Representations of Protein Fold Space and Application in Structure based Inference of Protein Function Books now! Available in PDF, ...

From Globular Proteins to Amyloids

From Globular Proteins to Amyloids
  • Author : Frederick Douglas Hamblin
  • Publisher : Elsevier
  • Release Date : 1968
  • Total pages : 73
  • ISBN : 1908818255
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Summary : "British units are used throughout the book."...

Manufacture Engineering Quality and Production System II

Manufacture Engineering  Quality and Production System II
  • Author : Yiyi Zhouzhou
  • Publisher : Trans Tech Publications Ltd
  • Release Date : 2013-06-27
  • Total pages : 860
  • ISBN : 1908818255
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Summary : Selected, peer reviewed papers from the 2013 2nd International Conference on Manufacture Engineering, Quality and Production System (ICMEQP 2013), February 27-28, 2013, Hong Kong, China...

Journal

Journal
  • Author : American Chemical Society
  • Publisher : Unknown
  • Release Date : 2004
  • Total pages : 212
  • ISBN : 1908818255
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Summary : Download or read online Journal written by American Chemical Society, published by which was released on 2004. Get Journal Books now! Available in PDF, ePub and Kindle....

Protein Misfolding Diseases

Protein Misfolding Diseases
  • Author : Cláudio M. Gomes
  • Publisher : Humana Press
  • Release Date : 2018-11-10
  • Total pages : 338
  • ISBN : 1908818255
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Summary : This detailed book gathers a broad collection of experimental approaches to assist researchers in setting up different methods to investigate protein conformational disorders. Beginning with a section on assays focusing on biophysical approaches to study protein (mis)folding, the volume continues with sections on cellular and proteostasis assays as well ...