Pharmacology in Drug Discovery and Development

Written By Terry Kenakin
Pharmacology in Drug Discovery and Development
  • Publsiher : Academic Press
  • Release : 21 October 2016
  • ISBN : 0128037539
  • Pages : 350 pages
  • Rating : 4/5 from 21 reviews
GET THIS BOOKPharmacology in Drug Discovery and Development


Read or download book entitled Pharmacology in Drug Discovery and Development written by Terry Kenakin which was release on 21 October 2016, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Pharmacology in Drug Discovery and Development: Understanding Drug Response, Second Edition, is an introductory resource illustrating how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. The concepts discussed in this book allow for the application of more predictive pharmacological procedures aimed at increasing therapeutic efficacy that will lead to more successful drug development. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization. This edition has been fully revised to address the latest advances and research related to real time kinetic assays, pluridimensional efficacy, signaling bias, irreversible and chemical antagonism, allosterically-induced bias, pharmacokinetics and safety, target and pathway validation, and much more. With numerous valuable chapter summaries, detailed references, practical examples and case studies throughout, Dr. Kenakin successfully navigates a highly complex subject, making it accessible for students, professors, and new researchers working in pharmacology and drug discovery. Includes example-based cases that illustrate how the pharmacological concepts discussed in this book lead to practical outcomes for further research Provides vignettes on those researchers and scientists who have contributed significantly to the fields of pharmacology and drug discovery throughout history Offers sample questions throughout the book and an appendix containing answers for self-testing and retention

Pharmacology in Drug Discovery and Development

Pharmacology in Drug Discovery and Development
  • Author : Terry Kenakin
  • Publisher : Academic Press
  • Release Date : 2016-10-21
  • Total pages : 350
  • ISBN : 0128037539
GET BOOK

Summary : Pharmacology in Drug Discovery and Development: Understanding Drug Response, Second Edition, is an introductory resource illustrating how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. The concepts discussed in this book ...

Drug Discovery and Development

Drug Discovery and Development
  • Author : H. P. Rang,Daniel Vasella
  • Publisher : Churchill Livingstone
  • Release Date : 2006
  • Total pages : 346
  • ISBN : 0128037539
GET BOOK

Summary : 'Drug Discovery and Development' describes the huge complexities involved in bringing a drug to market and how new molecular understanding and techniques can make the process more targeted and successful....

Translational Medicine

Translational Medicine
  • Author : Robert A. Meyers
  • Publisher : John Wiley & Sons
  • Release Date : 2018-07-16
  • Total pages : 1064
  • ISBN : 0128037539
GET BOOK

Summary : This reference work gives a compete overview of the different stages of drug development using a translational approach. The book is structured in different parts, following the different stages in drug development. Almost half of the work is dedicated to core of drug discovery using a translational approach, the identification ...

Drug Discovery Development

Drug Discovery   Development
  • Author : Bhushan Patwardhan
  • Publisher : New India Publishing
  • Release Date : 2007
  • Total pages : 362
  • ISBN : 0128037539
GET BOOK

Summary : While biotechnological advances, genomics and high throughput screenings or combinatorial and asymmetric syntheses are opening new opportunities in drug discovery, the industry is facing serious innovation deficit. The total number of new molecules registered per year has dropped in contrast to expected increase. Post marketing failures of blockbuster drugs have ...

Drug Discovery and Development

Drug Discovery and Development
  • Author : Ramarao Poduri
  • Publisher : Springer Nature
  • Release Date : 2021-04-17
  • Total pages : 212
  • ISBN : 0128037539
GET BOOK

Summary : Download or read online Drug Discovery and Development written by Ramarao Poduri, published by Springer Nature which was released on . Get Drug Discovery and Development Books now! Available in PDF, ePub and Kindle....

Drug Discovery and Evaluation Methods in Clinical Pharmacology

Drug Discovery and Evaluation  Methods in Clinical Pharmacology
  • Author : H.Gerhard Vogel,Jochen Maas,Alexander Gebauer
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-12-15
  • Total pages : 564
  • ISBN : 0128037539
GET BOOK

Summary : Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these ...

Drug Discovery and Development Third Edition

Drug Discovery and Development  Third Edition
  • Author : James J. O'Donnell,John Somberg,Vincent Idemyor,James T. O'Donnell
  • Publisher : CRC Press
  • Release Date : 2019-11-21
  • Total pages : 668
  • ISBN : 0128037539
GET BOOK

Summary : Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and evaluation of ...

Drug Discovery and Development

Drug Discovery and Development
  • Author : Omboon Vallisuta,Suleiman Olimat
  • Publisher : BoD – Books on Demand
  • Release Date : 2015-06-03
  • Total pages : 330
  • ISBN : 0128037539
GET BOOK

Summary : It is very important for scientists all over the globe to enhance drug discovery research for better human health. This book demonstrates that various expertise are essential for drug discovery including synthetic or natural drugs, clinical pharmacology, receptor identification, drug metabolism, pharmacodynamic and pharmacokinetic research. The following 5 sections cover diverse ...

The Science and Business of Drug Discovery

The Science and Business of Drug Discovery
  • Author : Edward D. Zanders
  • Publisher : Springer Nature
  • Release Date : 2020-12-11
  • Total pages : 402
  • ISBN : 0128037539
GET BOOK

Summary : The Science and Business of Drug Discovery is written for those who want to learn about the biopharmaceutical industry and its products whatever their level of technical knowledge. Its aim is to demystify the jargon used in drug development, but in a way that avoids over simplification and the resulting ...

Drug Discovery and Development E Book

Drug Discovery and Development   E Book
  • Author : Raymond G Hill
  • Publisher : Elsevier Health Sciences
  • Release Date : 2012-07-20
  • Total pages : 368
  • ISBN : 0128037539
GET BOOK

Summary : The modern pharmacopeia has enormous power to alleviate disease, and owes its existence almost entirely to the work of the pharmaceutical industry. This book provides an introduction to the way the industry goes about the discovery and development of new drugs. The first part gives a brief historical account from ...

Innovative Approaches in Drug Discovery

Innovative Approaches in Drug Discovery
  • Author : Bhushan Patwardhan,Rathnam Chaguturu
  • Publisher : Academic Press
  • Release Date : 2016-10-03
  • Total pages : 480
  • ISBN : 0128037539
GET BOOK

Summary : Despite considerable technological advances, the pharmaceutical industry is experiencing a severe innovation deficit, especially in the discovery of new drugs. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting provides a critical review and analysis of health, disease and medicine, and explores possible reasons behind the present crisis ...

Basic Principles of Drug Discovery and Development

Basic Principles of Drug Discovery and Development
  • Author : Benjamin Blass
  • Publisher : Elsevier
  • Release Date : 2015-04-24
  • Total pages : 580
  • ISBN : 0128037539
GET BOOK

Summary : Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, providing comprehensive explanations of enabling technologies such as high throughput screening, structure based drug design, molecular modeling, pharmaceutical profiling, and translational medicine, all areas that have become critical steps in ...

Textbook of Drug Design and Discovery

Textbook of Drug Design and Discovery
  • Author : Kristian Stromgaard,Povl Krogsgaard-Larsen,Ulf Madsen
  • Publisher : CRC Press
  • Release Date : 2009-10-07
  • Total pages : 476
  • ISBN : 0128037539
GET BOOK

Summary : The molecular biological revolution and the mapping of the human genome continue to provide new challenges and opportunities for drug research and design. Future medicinal chemists and drug designers must have a firm background in a number of related scientific disciplines in order to understand the conversion of new insight ...

Drug Discovery and Evaluation

Drug Discovery and Evaluation
  • Author : Hans G. Vogel,Wolfgang H. Vogel
  • Publisher : Springer
  • Release Date : 1997-04-09
  • Total pages : 757
  • ISBN : 0128037539
GET BOOK

Summary : Comprehensive reference on 700 of the most frequently used assays for reliably detecting pharmacological effects of potential drugs. For practitioners and students. Includes a full-text CD-ROM....

Pharmacology for Chemists

Pharmacology for Chemists
  • Author : Raymond Hill,Terry Kenakin,Tom Blackburn
  • Publisher : Royal Society of Chemistry
  • Release Date : 2017-10-30
  • Total pages : 524
  • ISBN : 0128037539
GET BOOK

Summary : Download or read online Pharmacology for Chemists written by Raymond Hill,Terry Kenakin,Tom Blackburn, published by Royal Society of Chemistry which was released on 2017-10-30. Get Pharmacology for Chemists Books now! Available in PDF, ePub and Kindle....