Overflow Metabolism

Written By Alexei Vazquez
Overflow Metabolism
  • Publsiher : Academic Press
  • Release : 27 October 2017
  • ISBN : 0128123354
  • Pages : 84 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Overflow Metabolism written by Alexei Vazquez which was release on 27 October 2017, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Overflow Metabolism: From Yeast to Marathon Runners provides an overview of overflow metabolism, reviewing the major phenomenological aspects as observed in different organisms, followed by a critical analysis of proposed theories to explain overflow metabolism. In our ideal view of metabolism, we think of catabolism and anabolism. In catabolism nutrients break down to carbon dioxide and water to generate biochemical energy. In anabolism nutrients break down to generate building blocks for cell biosynthesis. Yet, when cells are pushed to high metabolic rates they exhibit incomplete catabolism of nutrients, with a lower energy yield and excretion of metabolic byproducts. This phenomenon, characterized by the excretion of metabolic byproducts that could otherwise be used for catabolism or anabolism, is generally known as overflow metabolism. Overflow metabolism is a ubiquitous phenotype that has been conserved during evolution. Examples are the acetate switch in the bacterium E. coli, Crabtree effect in unicellular eukaryote yeasts, the lactate switch in sports medicine, and the Warburg effect in cancer. Several theories have been proposed to explain this seemingly wasteful phenotype. Yet, there is no consensus about what determines overflow metabolism and whether it offers any selective advantage. Includes examples of overflow metabolism and major phenomenological features Features a critical view of proposed theories to explain overflow metabolism Provides a summary of our preview work, proposing molecular crowding as the cause of overflow metabolism, together with new unpublished results

Overflow Metabolism

Overflow Metabolism
  • Author : Alexei Vazquez
  • Publisher : Academic Press
  • Release Date : 2017-10-27
  • Total pages : 84
  • ISBN : 0128123354
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Summary : Overflow Metabolism: From Yeast to Marathon Runners provides an overview of overflow metabolism, reviewing the major phenomenological aspects as observed in different organisms, followed by a critical analysis of proposed theories to explain overflow metabolism. In our ideal view of metabolism, we think of catabolism and anabolism. In catabolism nutrients ...

The significance of overflow metabolism in the physiology and g

The significance of overflow metabolism in the physiology and g
  • Author : Oense Martinus Neijssel
  • Publisher : Unknown
  • Release Date : 1976
  • Total pages : 212
  • ISBN : 0128123354
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  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1948
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  • ISBN : 0128123354
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  • Publisher : Oxford University Press, USA
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  • ISBN : 0128123354
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  • ISBN : 0128123354
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  • Publisher : CRC Press
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Summary : First Published in 1989, this book explores the relationship between plants and insects and the ways in which they interact with each other. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for students of oncology, and other practitioners in ...

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  • Release Date : 1987
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  • Publisher : Unknown
  • Release Date : 1994
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  • ISBN : 0128123354
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  • Author : Wiebe Olijve
  • Publisher : Unknown
  • Release Date : 1978
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  • ISBN : 0128123354
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  • Publisher : Wiley-Blackwell
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Summary : Biotechnology Second, Completely Revised Edition Edited by H.-J. Rehm and G. Reed in cooperation with A. Pühler and P. Stadler This fully revised and expanded Second Edition takes into account all recent developments in biotechnology. It is extraordinarily broad in scope, up-to-date, carefully structured and well-balanced. 'Biotechnology' considers ...

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  • ISBN : 0128123354
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Summary : Download or read online The Effect of Cations on Microbial Metabolism and Growth Energetics written by Ed T. Buurman, published by which was released on 1991. Get The Effect of Cations on Microbial Metabolism and Growth Energetics Books now! Available in PDF, ePub and Kindle....

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  • ISBN : 0128123354
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Summary : Download or read online Biotechnology a Comprehensive Treatise in 8 Volumes written by Hans-Jürgen Rehm,Gerald Reed, published by which was released on 1981. Get Biotechnology a Comprehensive Treatise in 8 Volumes Books now! Available in PDF, ePub and Kindle....