Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC

Written By Anthony Faber
Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC
  • Publsiher : Academic Press
  • Release : 15 March 2021
  • ISBN : 9780128228333
  • Pages : 250 pages
  • Rating : 4/5 from 21 reviews
GET THIS BOOKOvercoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC


Read or download book entitled Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC written by Anthony Faber which was release on 15 March 2021, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC, Volume 17 presents updated information on how EGFR mutant lung cancers evolve to evade EGFR inhibitors, clinical strategies that identify these mechanisms, and how to implement newer therapeutic strategies to combat resistance and improve patient survival. As resistance to EGFR inhibitors is often through re-activation of MEK/ERK and PI3K pathways, or through loss of cell death responses, there is much overlap with resistance to targeted therapies in other paradigms, such as BRAF inhibitors in BRAF mutant melanoma, and HER2 inhibitors in HER2 amplified breast cancer. This book is a valuable resource for cancer researchers, clinicians, graduate students and other members of the biomedical field who are interested in promising treatments for lung cancer. Presents historical context on how NSCLC and SCLC has been treated, with an emphasis on NSCLC and how the concept of EGFR inhibitors has been implemented Discusses critical resistant mechanisms seen in the clinic to 1st, 2nd and 3rd generation EGFR inhibitors Encompasses the current state of affairs in clinical trials to address resistance

Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC

Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC
  • Author : Anthony Faber
  • Publisher : Academic Press
  • Release Date : 2021-03-15
  • Total pages : 250
  • ISBN : 9780128228333
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Summary : Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC, Volume 17 presents updated information on how EGFR mutant lung cancers evolve to evade EGFR inhibitors, clinical strategies that identify these mechanisms, and how to implement newer therapeutic strategies to combat resistance and improve patient survival. As resistance to EGFR inhibitors is ...

Cancer Research

Cancer Research
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 212
  • ISBN : 9780128228333
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Summary : Download or read online Cancer Research written by , published by which was released on 2008. Get Cancer Research Books now! Available in PDF, ePub and Kindle....

Handbook of Cell Signaling

Handbook of Cell Signaling
  • Author : Ralph A. Bradshaw,Edward A. Dennis
  • Publisher : Academic Press
  • Release Date : 2010
  • Total pages : 3047
  • ISBN : 9780128228333
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Summary : KEY FEATURES: * Contains over 350 chapters of comprehensive coverage on cell signaling * Includes discussion on topics from ligand/receptor interactions to organ/organism responses * Provides user-friendly, well-illustrated, reputable content by experts in the field DESCRIPTION: Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular ...

Oncology

Oncology
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 212
  • ISBN : 9780128228333
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Summary : Download or read online Oncology written by , published by which was released on 2008. Get Oncology Books now! Available in PDF, ePub and Kindle....

Clinical Pharmacology for Prescribing

Clinical Pharmacology for Prescribing
  • Author : Federico Dajas-Bailador
  • Publisher : Oxford University Press, USA
  • Release Date : 2019-09-16
  • Total pages : 752
  • ISBN : 9780128228333
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Summary : Clinical Pharmacology for Prescribing explains how drugs work and why they should be prescribed for common medical conditions. Linking disease processes to pharmacological interventions, this guide gives a sound basis for evidence based prescribing. Written for medical students, trainee doctors and non-medical prescribers, it addresses all aspects of practical pharmacology, ...

The New England Journal of Medicine

The New England Journal of Medicine
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 212
  • ISBN : 9780128228333
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Summary : Download or read online The New England Journal of Medicine written by , published by which was released on 2008. Get The New England Journal of Medicine Books now! Available in PDF, ePub and Kindle....

Single Cell Omics

Single Cell Omics
  • Author : Debmalya Barh,Vasco Azevedo
  • Publisher : Academic Press
  • Release Date : 2019-07-31
  • Total pages : 384
  • ISBN : 9780128228333
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Summary : Single-cell Omics, Volume 2: Advances in Applications provides the latest single-cell omics applications in the field of biomedicine. The advent of omics technologies have enabled us to identify the differences between cell types and subpopulations at the level of the genome, proteome, transcriptome, epigenome, and in several other fields of omics. ...

Oxford Textbook of Cancer in Children

Oxford Textbook of Cancer in Children
  • Author : Hubert N. Caron,Andrea Biondi,Tom Boterberg,François Doz
  • Publisher : Oxford University Press, USA
  • Release Date : 2020-03-12
  • Total pages : 312
  • ISBN : 9780128228333
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Summary : The Oxford Textbook of Cancer in Children is a well-established and highly regarded text providing clear and up-to-date clinical guidance on the optimal management of childhood cancers....

American Journal of Respiratory and Critical Care Medicine

American Journal of Respiratory and Critical Care Medicine
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 212
  • ISBN : 9780128228333
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Summary : Download or read online American Journal of Respiratory and Critical Care Medicine written by , published by which was released on 2007. Get American Journal of Respiratory and Critical Care Medicine Books now! Available in PDF, ePub and Kindle....

Current Applications for Overcoming Resistance to Targeted Therapies

Current Applications for Overcoming Resistance to Targeted Therapies
  • Author : Myron R. Szewczuk,Bessi Qorri,Manpreet Sambi
  • Publisher : Springer
  • Release Date : 2019-07-15
  • Total pages : 320
  • ISBN : 9780128228333
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Summary : Targeted therapies were initially developed to exploit the upregulation and dependence on key oncogenic pathways critical to cancer progression. Additionally, they also presented as a method to overcome chemoresistance by supplementing conventional therapeutic regimens with targeted therapies. However, the development of resistance to these combinatorial approaches has led to the ...

Journal of the National Cancer Institute

Journal of the National Cancer Institute
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2006
  • Total pages : 212
  • ISBN : 9780128228333
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Summary : Download or read online Journal of the National Cancer Institute written by , published by which was released on 2006. Get Journal of the National Cancer Institute Books now! Available in PDF, ePub and Kindle....

Compendium of Awards

Compendium of Awards
  • Author : Tobacco-Related Disease Research Program (University of California (System))
  • Publisher : Unknown
  • Release Date : 2002
  • Total pages : 212
  • ISBN : 9780128228333
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Summary : Download or read online Compendium of Awards written by Tobacco-Related Disease Research Program (University of California (System)), published by which was released on 2002. Get Compendium of Awards Books now! Available in PDF, ePub and Kindle....

Annual Meeting Proceedings

Annual Meeting Proceedings
  • Author : American Society of Clinical Oncology. Meeting
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 212
  • ISBN : 9780128228333
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Summary : Download or read online Annual Meeting Proceedings written by American Society of Clinical Oncology. Meeting, published by which was released on 2008. Get Annual Meeting Proceedings Books now! Available in PDF, ePub and Kindle....

Comparative Medicine

Comparative Medicine
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 212
  • ISBN : 9780128228333
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Summary : Download or read online Comparative Medicine written by , published by which was released on 2008. Get Comparative Medicine Books now! Available in PDF, ePub and Kindle....

Quantitative Imaging Tools for Lung Cancer Drug Assessment

Quantitative Imaging Tools for Lung Cancer Drug Assessment
  • Author : James L. Mulshine,Thomas M. Baer
  • Publisher : Wiley-OSA
  • Release Date : 2008-04-14
  • Total pages : 162
  • ISBN : 9780128228333
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Summary : Preface (Thomas M. BAer and James L. MUlshine). Chapter 1: Incorporating Imaging into Drug Development: An Industry Perspective (Philip S. MUrphy and Debasish Roychowdhury). Chapter 2: Developing Imaging Tools for Drug Development: Critical Technology, Clinical Data and Regulatory (Rafal Dziadziuszko, Fred R. HIrsch and Paul A. BUnn, Jr). Chapter 3: Quantitative Imaging in ...