Overcoming Ovarian Cancer Chemoresistance

Written By Goli Samimi
Overcoming Ovarian Cancer Chemoresistance
  • Publsiher : Academic Press
  • Release : 06 November 2020
  • ISBN : 0128198419
  • Pages : 188 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Overcoming Ovarian Cancer Chemoresistance written by Goli Samimi which was release on 06 November 2020, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Overcoming Ovarian Cancer Chemoresistance presents non-overlapping review chapters that discuss the state of the field in overcoming chemoresistance of ovarian cancer and treatment options before and following recurrence, considering the genetic makeup of the ovarian cancer patient and her tumor. With the uptake of both germline and somatic gene testing, clinicians can obtain a more comprehensive understanding of ovarian tumors and this book provides information to link the genetic makeup of a tumor (or patient) with the best available treatment. The book discusses topics such as strategies to fight chemo-resistance in ovarian cancer, circulating DNA as a monitor of response, BRCA mutations, ovarian cancer stem cells, immunotherapy and vaccines. Additionally, it brings a list of promising agents at clinical and pre-clinical stage that will impact the treatment in the near future. This book is a valuable source for cancer researchers, oncologists and several members of biomedical field who need to understand how to battle chemoresistance in ovarian cancer. Provides a comprehensive view of both biological and genetic determinants of resistance, as well as technical approaches to monitor response Discusses genetic reversions as a unique alteration and a new field of study Includes a chapter on upcoming and promising agents that are in the pre-clinical and early clinical space, to set the stage for future directions in the field

Overcoming Ovarian Cancer Chemoresistance

Overcoming Ovarian Cancer Chemoresistance
  • Author : Goli Samimi,Christina Annunziata
  • Publisher : Academic Press
  • Release Date : 2020-11-06
  • Total pages : 188
  • ISBN : 0128198419
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Summary : Overcoming Ovarian Cancer Chemoresistance presents non-overlapping review chapters that discuss the state of the field in overcoming chemoresistance of ovarian cancer and treatment options before and following recurrence, considering the genetic makeup of the ovarian cancer patient and her tumor. With the uptake of both germline and somatic gene testing, ...

Overcoming Drug Resistance in Gynecologic Cancers

Overcoming Drug Resistance in Gynecologic Cancers
  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2021-09-03
  • Total pages : 388
  • ISBN : 0128198419
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Summary : Overcoming Drug Resistance in Gynecologic Cancers provides up-to-date information related to important gynecologic cancers and focuses on mechanisms of drug resistance, genetics, signaling, immunology, health disparities, nanotechnology, economic considerations and financial impacts. The book covers not only drug resistance but also important means to reverse resistance both in the laboratory ...

Cancer Cell Chemoresistance and Chemosensitization

Cancer Cell Chemoresistance and Chemosensitization
  • Author : Ajaikumar B. Kunnumakkara,Devivasha Bordoloi,Javadi Monisha
  • Publisher : World Scientific
  • Release Date : 2018
  • Total pages : 212
  • ISBN : 0128198419
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Summary : Download or read online Cancer Cell Chemoresistance and Chemosensitization written by Ajaikumar B. Kunnumakkara,Devivasha Bordoloi,Javadi Monisha, published by World Scientific which was released on 2018. Get Cancer Cell Chemoresistance and Chemosensitization Books now! Available in PDF, ePub and Kindle....

Development of a Patient derived Xenograft Model of Ovarian Cancer to Characterize the Chemotherapy Resistant Population

Development of a Patient derived Xenograft Model of Ovarian Cancer to Characterize the Chemotherapy Resistant Population
  • Author : Zachary Christopher Dobbin
  • Publisher : Unknown
  • Release Date : 2014
  • Total pages : 131
  • ISBN : 0128198419
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Summary : Ovarian cancer while the second most common gynecologic malignancy is the most commons cause of death due to a gynecologic malignancy and the fifth most common cause of death to cancer in women. In 2014, there will be an expected 21,980 cases and 14,270 deaths. Unfortunately, the five-year survival for ovarian cancer is ...

Current Applications for Overcoming Resistance to Targeted Therapies

Current Applications for Overcoming Resistance to Targeted Therapies
  • Author : Myron R. Szewczuk,Bessi Qorri,Manpreet Sambi
  • Publisher : Springer
  • Release Date : 2019-07-15
  • Total pages : 320
  • ISBN : 0128198419
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Summary : Targeted therapies were initially developed to exploit the upregulation and dependence on key oncogenic pathways critical to cancer progression. Additionally, they also presented as a method to overcome chemoresistance by supplementing conventional therapeutic regimens with targeted therapies. However, the development of resistance to these combinatorial approaches has led to the ...

Epigenetic Regulation in Overcoming Chemoresistance

Epigenetic Regulation in Overcoming Chemoresistance
  • Author : Chunfu Wu,Lihui Wang
  • Publisher : Academic Press
  • Release Date : 2021-06-26
  • Total pages : 144
  • ISBN : 0128198419
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Summary : Epigenetic Regulation in Overcoming Chemoresistance, Volume 19, explains how epigenetic agents can enhance the chemotherapy sensitivity of diverse types of cancers. The book provides a comprehensive delineation and the recent development of the scientific studies on the epigenetic regulation in enhancing chemo-sensitivity. In addition, it discusses several topics such as DNA ...

Advances in Epithelial Ovarian Cancer Model Systems Microenvironmental Influences Therapy and Origins

Advances in Epithelial Ovarian Cancer  Model Systems  Microenvironmental Influences  Therapy  and Origins
  • Author : Viive Maarika Howell,Ben Davidson,TIAN-Li WANG,Christina Annunziata
  • Publisher : Frontiers Media SA
  • Release Date : 2016-02-03
  • Total pages : 212
  • ISBN : 0128198419
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Summary : This eBook provides a compendium of the current state-of-the-art in research tools for, and understanding of, the critical research areas in epithelial ovarian cancer (EOC) with a strong emphasis on (HG-SOC). Research areas covered include therapy response and development, microenvironmental influences and the etiology and progression of EOC. Ten articles ...

Overcoming Drug Resistance in Gynecologic Cancers

Overcoming Drug Resistance in Gynecologic Cancers
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2021-08-11
  • Total pages : 388
  • ISBN : 0128198419
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Summary : Overcoming Drug Resistance in Gynecologic Cancers provides up-to-date information related to important gynecologic cancers and focuses on mechanisms of drug resistance, genetics, signaling, immunology, health disparities, nanotechnology, economic considerations and financial impacts. The book covers not only drug resistance but also important means to reverse resistance both in the laboratory ...

Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance

Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance
  • Author : Andrew Freywald,Franco Vizeacoumar
  • Publisher : Academic Press
  • Release Date : 2020-12-04
  • Total pages : 308
  • ISBN : 0128198419
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Summary : Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance, Volume 12, discusses new approaches that are being undertaken to counteract tumor plasticity, understand and tackle the interactions with the microenvironment, and disrupt the rewiring of malignant cells or bypass biological mechanism of resistance by using targeted radionuclide therapies. This ...

Role of Nutraceuticals in Cancer Chemosensitization

Role of Nutraceuticals in Cancer Chemosensitization
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2017-10-18
  • Total pages : 398
  • ISBN : 0128198419
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Summary : Role of Nutraceuticals in Chemoresistance to Cancer, Volume Two, focuses on nutraceuticals, the compounds derived from natural sources, which are usually multi-targeted as a means to overcome chemoresistance. This book discusses the role of several compounds related to nutraceuticals and chemoresistance, such as curcumin, resveratrol, indole 3-carbinol, tocotrienols, ursolic acid, ...

Your Life In Your Hands

Your Life In Your Hands
  • Author : Jane Plant
  • Publisher : Random House
  • Release Date : 2012-01-31
  • Total pages : 544
  • ISBN : 0128198419
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Summary : Professor Jane Plant's international bestseller on combating breast cancer through diet and lifestyle changes has been fully revised and updated, including new information on ovarian cancer and other types of cancer. In this groundbreaking book, Professor Plant details her own experiences of suffering with breast cancer, and how she learnt ...

Phosphoinositide 3 Kinase AKT1 Pathway and Human Ovarian Cancer

Phosphoinositide 3 Kinase AKT1 Pathway and Human Ovarian Cancer
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2003
  • Total pages : 95
  • ISBN : 0128198419
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Summary : During the last three years, we have demonstrated frequent activation (39%) of PI3K/AKT1 pathway in human primary ovarian cancer. The activation of this pathway is associated with late stage and high grade tumors, indicating that activation of PI3K/AKT1 plays a important role in ovarian tumor progression rather ...

Therapeutic Strategies to Overcome ALK Resistance in Cancer

Therapeutic Strategies to Overcome ALK Resistance in Cancer
  • Author : Luc Friboulet
  • Publisher : Academic Press
  • Release Date : 2021-01-18
  • Total pages : 216
  • ISBN : 0128198419
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Summary : Therapeutic Strategies to Overcome ALK Resistance in Cancer, Volume 13, presents current strategies to improve and prolong clinical benefit in ALK driven cancers. Most patients with ALK-driven cancer are sensitive to tyrosine kinase inhibitor (TKI) therapy, but resistance invariably develops. This book discusses topics such as structure and function of ALK, ...

Glioblastoma Resistance to Chemotherapy Molecular Mechanisms and Innovative Reversal Strategies

Glioblastoma Resistance to Chemotherapy  Molecular Mechanisms and Innovative Reversal Strategies
  • Author : Ramasamy Paulmurugan,Tarik F. Massoud
  • Publisher : Academic Press
  • Release Date : 2021-06-25
  • Total pages : 828
  • ISBN : 0128198419
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Summary : Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and ...

Drug Resistance in Colorectal Cancer Molecular Mechanisms and Therapeutic Strategies

Drug Resistance in Colorectal Cancer  Molecular Mechanisms and Therapeutic Strategies
  • Author : Chi Hin Cho,Tao Hu
  • Publisher : Academic Press
  • Release Date : 2020-05-24
  • Total pages : 240
  • ISBN : 0128198419
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Summary : Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies, Volume Eight, summarizes the molecular mechanisms of drug resistance in colorectal cancer, along with the most up-to-date therapeutic strategies available. The book discusses reasons why colorectal tumors become refractory during the progression of the disease, but also explains how drug ...