The Oncogenomics Handbook

Written By William J. LaRochelle
The Oncogenomics Handbook
  • Publsiher : Springer Science & Business Media
  • Release : 09 November 2007
  • ISBN : 1592598935
  • Pages : 750 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled The Oncogenomics Handbook written by William J. LaRochelle which was release on 09 November 2007, this book published by Springer Science & Business Media. Available in PDF, EPUB and Kindle Format. Book excerpt: An integrated overview of cancer drug discovery and development from the bench to the clinic, showing with broad strokes and representative examples the drug development process as a network of linked components leading from the discovered target to the ultimate therapeutic product. Following a systems biology approach, the authors explain genomic databases and how to discover oncological targets from them, how then to advance from the gene and transcript to the level of protein biochemistry, how next to move from the chemical realm to that of the living cell and, ultimately, pursue animal modeling and clinical development. Emerging cancer therapeutics including Ritux an, Erbitux, Gleevec Herceptin, Avastin, ABX-EGF, Velcade, Kepivance, Iressa, Tarceva, and Zevalin are addressed. Highlights include cancer genomics, pharmacogenomics, transcriptomics, gene expression analysis, proteomic and enzymatic cancer profiling technologies, and cellular and animal approaches to cancer target validation.

The Oncogenomics Handbook

The Oncogenomics Handbook
  • Author : William J. LaRochelle,Richard A. Shimkets
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-11-09
  • Total pages : 750
  • ISBN : 1592598935
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Summary : An integrated overview of cancer drug discovery and development from the bench to the clinic, showing with broad strokes and representative examples the drug development process as a network of linked components leading from the discovered target to the ultimate therapeutic product. Following a systems biology approach, the authors explain ...

Oncogenomics

Oncogenomics
  • Author : Charles Brenner,David Duggan
  • Publisher : John Wiley & Sons
  • Release Date : 2004-11-19
  • Total pages : 400
  • ISBN : 1592598935
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Summary : This book aims to assemble the only available rigorous, yet broadly accessible introduction to this new and exciting field. Oncogenomics: Molecular Approaches to Cancer is approachable by basic scientists, practitioners, and other health professionals required to familiarize themselves with the tremendous impact of genomics and proteomics on cancer research. Clearly ...

Oncogenomics

Oncogenomics
  • Author : Franco Dammacco,Franco Silvestris
  • Publisher : Academic Press
  • Release Date : 2018-10-30
  • Total pages : 718
  • ISBN : 1592598935
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Summary : Oncogenomics: From Basic Research to Precision Medicine offers a thorough survey of precision medicine and its diagnostic and therapeutic applications in oncology. Gathering contributions from leading international researchers in the field, chapters examine recent translational advances in oncogenomic methods and technologies, detailing novel molecular classifications of tumors as well as ...

Oncogenomics and Cancer Proteomics

Oncogenomics and Cancer Proteomics
  • Author : Cesar Lopez-Camarillo,Elena Arechaga-Ocampo
  • Publisher : BoD – Books on Demand
  • Release Date : 2013-03-13
  • Total pages : 240
  • ISBN : 1592598935
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Summary : Oncogenomics and Cancer Proteomics - Novel Approaches in Biomarkers Discovery and Therapeutic Targets in Cancer presents comprehensive reviews of the most common cancers from bench to bedside applications by an international team of experts. This book will contribute to the scientific and medical community by providing up-to-date discoveries of oncogenomics ...

Systems and Integrative Approaches in Oncogenomics

Systems and Integrative Approaches in Oncogenomics
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2002
  • Total pages : 212
  • ISBN : 1592598935
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Summary : Significant progress in technology has allowed systems level molecular profiling of cancer which has created a wealth of unprecedented genomics ('oncogenomics') data. Innovative and integrated approaches are needed to translate this rich information into knowledge. In this dissertation, I have explored 3 such case studies involving high throughput datasets such as ...

A Computational Approach for Comparative Oncogenomics Using Mouse Models

A Computational Approach for Comparative Oncogenomics Using Mouse Models
  • Author : Benjamin Thomas Brett,University of Iowa. Interdisciplinary Graduate Program in Genetics
  • Publisher : Unknown
  • Release Date : 2014
  • Total pages : 109
  • ISBN : 1592598935
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Summary : Combining this connectivity network with the set of cancer genes identified by the Integration Analysis System is a strategy for rapid and efficient interpretation of the genetic results....

Translational Oncogenomics and Human Cancer Interactomics Advanced Techniques and Complex System Dynamic Approaches

Translational Oncogenomics and Human Cancer Interactomics  Advanced Techniques and Complex System Dynamic Approaches
  • Author : I. C. Baianu
  • Publisher : Unknown
  • Release Date : 2011
  • Total pages : 212
  • ISBN : 1592598935
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Summary : Download or read online Translational Oncogenomics and Human Cancer Interactomics Advanced Techniques and Complex System Dynamic Approaches written by I. C. Baianu, published by which was released on 2011. Get Translational Oncogenomics and Human Cancer Interactomics Advanced Techniques and Complex System Dynamic Approaches Books now! Available in PDF, ePub and Kindle....

Systems and Integrative Approaches in Oncogenomics

Systems and Integrative Approaches in Oncogenomics
  • Author : Gopinath Ganji
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 109
  • ISBN : 1592598935
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Summary : Download or read online Systems and Integrative Approaches in Oncogenomics written by Gopinath Ganji, published by which was released on 2009. Get Systems and Integrative Approaches in Oncogenomics Books now! Available in PDF, ePub and Kindle....

Applications of Biotechnology in Oncology

Applications of Biotechnology in Oncology
  • Author : Kewal K. Jain
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-11-19
  • Total pages : 855
  • ISBN : 1592598935
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Summary : Applications of Biotechnology in Oncology collects key writings by Kewal K. Jain on the most important contributions of biotechnology to cancer research, particularly to the molecular diagnosis of cancer and drug delivery in cancer for personalized management of patients. Basics of various “omics” technologies and their application in oncology are ...

Advances in Biology and Therapy of Multiple Myeloma

Advances in Biology and Therapy of Multiple Myeloma
  • Author : Nikhil C. Munshi,Kenneth C. Anderson
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-11-15
  • Total pages : 322
  • ISBN : 1592598935
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Summary : Despite the advances in conventional, novel agent and high dose chemotherapy multiple myeloma (MM) remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in MM focusing on the development of molecularly-based combination therapies has great ...

Applied Genomics and Proteomics

Applied Genomics and Proteomics
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2002
  • Total pages : 212
  • ISBN : 1592598935
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Summary : Download or read online Applied Genomics and Proteomics written by , published by which was released on 2002. Get Applied Genomics and Proteomics Books now! Available in PDF, ePub and Kindle....

Advances in Biology and Therapy of Multiple Myeloma

Advances in Biology and Therapy of Multiple Myeloma
  • Author : Nikhil C. Munshi,Kenneth C. Anderson
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-09
  • Total pages : 290
  • ISBN : 1592598935
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Summary : Despite the advances in conventional, novel agent and high dose chemotherapy multiple myeloma (MM) remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in MM focusing on the development of molecularly-based combination therapies has great ...

Critical Issues in Head and Neck Oncology

Critical Issues in Head and Neck Oncology
  • Author : Jan B. Vermorken,Volker Budach,C. René Leemans,Jean-Pascal Machiels,Piero Nicolai,Brian O'Sullivan
  • Publisher : Springer
  • Release Date : 2018-11-12
  • Total pages : 363
  • ISBN : 1592598935
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Summary : This book provides an overview of the latest advances in head and neck cancer using a multidisciplinary approach. Commencing with a discussion of epidemiological and diagnostic aspects, including the role of vaccination and key pathological features, the book then follows by examining the role of oncogenomics, proteomics, next generation sequencing ...

Cancer Forum

Cancer Forum
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2002
  • Total pages : 212
  • ISBN : 1592598935
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Summary : Download or read online Cancer Forum written by , published by which was released on 2002. Get Cancer Forum Books now! Available in PDF, ePub and Kindle....

Oncogenomics and Cancer Proteomics

Oncogenomics and Cancer Proteomics
  • Author : Cesar Lopez-Camarillo,Elena Arechaga-Ocampo
  • Publisher : IntechOpen
  • Release Date : 2013-03-13
  • Total pages : 240
  • ISBN : 1592598935
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Summary : Oncogenomics and Cancer Proteomics - Novel Approaches in Biomarkers Discovery and Therapeutic Targets in Cancer presents comprehensive reviews of the most common cancers from bench to bedside applications by an international team of experts. This book will contribute to the scientific and medical community by providing up-to-date discoveries of oncogenomics ...