Novel Sensitizing Agents for Therapeutic Anti EGFR Antibodies

Written By Shi Hu
Novel Sensitizing Agents for Therapeutic Anti EGFR Antibodies
  • Publsiher : Academic Press
  • Release : 15 March 2021
  • ISBN : 9780128215845
  • Pages : 300 pages
  • Rating : 4/5 from 21 reviews
GET THIS BOOKNovel Sensitizing Agents for Therapeutic Anti EGFR Antibodies


Read or download book entitled Novel Sensitizing Agents for Therapeutic Anti EGFR Antibodies written by Shi Hu which was release on 15 March 2021, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Novel Sensitizing Agents for Therapeutic Anti-EGFR Antibodies presents an in-depth description of sensitizers to overcome resistance to anti-EGFR targeted antibody therapies in cancer, including novel engineered antibody drugs or other sensitizers. It gives an insight into the landscape of anti-EGFR based cancer treatment, the challenges of targeted therapy, and a glimpse into the future of antibody therapy. The book offers pertinent basic science information on strategies used for the rational design and discovery of novel sensitizing agents, and, in addition, translational studies involving pre-clinical and clinical design and execution with these novel agents. It covers basic science strategies that are being used in drug discovery and preclinical evaluation focused on EGFR blockage resistance, as well as clinical trial methodology including clinical pharmacokinetics and imaging to address issues of efficacy evaluation of the new anticancer sensitizers for anti-EGFR drug resistance. This book is an indispensable resource for cancer researchers, medicinal chemists, and other biomedical scientists involved in the development of new therapeutic agents to overcome resistance to anti-EGFR treatments. Presents detailed description of history, chemistry, mechanism of action, structure-function relationships, pharmacology, side effects, dosing, and formulation of new sensitizers to anti-EGFR antibodies Provides molecular structures for all novel anticancer drugs and strategies to overcome resistance of anti-EGFR antibodies Encompasses up-to-date information on the cancer drug discovery process, including new research tools, tumor-targeting strategies, and fundamental concepts in the emerging areas of precision medicine

Novel Sensitizing Agents for Therapeutic Anti EGFR Antibodies

Novel Sensitizing Agents for Therapeutic Anti EGFR Antibodies
  • Author : Shi Hu
  • Publisher : Academic Press
  • Release Date : 2021-03-15
  • Total pages : 300
  • ISBN : 9780128215845
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Summary : Novel Sensitizing Agents for Therapeutic Anti-EGFR Antibodies presents an in-depth description of sensitizers to overcome resistance to anti-EGFR targeted antibody therapies in cancer, including novel engineered antibody drugs or other sensitizers. It gives an insight into the landscape of anti-EGFR based cancer treatment, the challenges of targeted therapy, and a ...

Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy

Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy
  • Author : Dong-hua Yang
  • Publisher : Cancer Sensitizing Agents for
  • Release Date : 2018-11-15
  • Total pages : 300
  • ISBN : 9780128215845
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Summary : Tyrosine Kinase Inhibitors as Sensitizing Agents for Chemotherapy, Volume Four in the Cancer Sensitizing Agents for Chemotherapy Series focuses on strategic combination therapies that involve a variety of tyrosine kinase inhibitors working together to overcome multi-drug resistance in cancer cells. The book discusses several tyrosine kinase inhibitors that have been ...

Novel Anticancer Agents

Novel Anticancer Agents
  • Author : Alex A. Adjei,John K. Buolamwini
  • Publisher : Academic Press
  • Release Date : 2011-04-28
  • Total pages : 464
  • ISBN : 9780128215845
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Summary : This book offers pertinent basic science information on strategies used for the rational design and discovery of novel anticancer agents, and, in addition, translational studies involving clinical trial design and execution with these novel, mostly cytostatic agents. This book covers basic science strategies that are being used in drug discovery ...

Novel Therapies in Head and Neck Cancer Beyond the Horizon

Novel Therapies in Head and Neck Cancer  Beyond the Horizon
  • Author : Maie A. St. John,No hee Park
  • Publisher : Academic Press
  • Release Date : 2020-06-29
  • Total pages : 266
  • ISBN : 9780128215845
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Summary : Novel Therapies in Head and Neck Cancer: Beyond the Horizon, Volume Twelve, provides a high-level synthesis of the latest treatments and outcomes relating to head and neck cancer. Chemotherapy and immunotherapy for those cancer types are rapidly evolving, and an updated source based on the expertise of internationally renowned researchers ...

Resistance to Immunotherapeutic Antibodies in Cancer

Resistance to Immunotherapeutic Antibodies in Cancer
  • Author : Benjamin Bonavida
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-08-04
  • Total pages : 202
  • ISBN : 9780128215845
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Summary : ​​​​The traditional approaches to treat various cancers include chemotherapy, radiation and/or hormonal therapy. While these therapies continue to be effective in large part, they are not selective and highly toxic. There have been encouraging results in alternative therapeutic approach called antibody-mediated anti-cancer therapy, which is less toxic, more selective, ...

Sensitization of Cancer Cells for Chemo Immuno Radio therapy

Sensitization of Cancer Cells for Chemo Immuno Radio therapy
  • Author : Benjamin Bonavida
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-07-31
  • Total pages : 420
  • ISBN : 9780128215845
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Summary : This book reviews novel approaches developed to reverse tumor cell resistance to chemo/immuno/radio-therapy and the use of various sensitizing agents in combination with various cytotoxics. It also introduces several current approaches developed by established investigators that are aimed at overcoming resistance. This is the first volume to compile ...

Abeloff s Clinical Oncology E Book

Abeloff s Clinical Oncology E Book
  • Author : John E. Niederhuber,James O. Armitage,James H Doroshow,Michael B. Kastan,Joel E. Tepper
  • Publisher : Elsevier Health Sciences
  • Release Date : 2019-01-08
  • Total pages : 2208
  • ISBN : 9780128215845
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Summary : Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it ...

Radiosensitizers and Radiochemotherapy in the Treatment of Cancer

Radiosensitizers and Radiochemotherapy in the Treatment of Cancer
  • Author : Shirley Lehnert
  • Publisher : CRC Press
  • Release Date : 2014-12-08
  • Total pages : 548
  • ISBN : 9780128215845
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Summary : Radiosensitizers and Radiochemotherapy in the Treatment of Cancer catalogs and describes the mechanism of action for entities characterized as radiosensitizers. Developments in the biological and physical sciences have introduced new radiosensitizers and defined novel targets for radiosensitization. As a result, a book about radiosensitization must now address a huge range ...

Clinical Radiation Oncology E Book

Clinical Radiation Oncology E Book
  • Author : Leonard L. Gunderson,Joel E. Tepper
  • Publisher : Elsevier Health Sciences
  • Release Date : 2015-06-16
  • Total pages : 1638
  • ISBN : 9780128215845
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Summary : Perfect for radiation oncology physicians and residents needing a multidisciplinary, treatment-focused resource, this updated edition continues to provide the latest knowledge in this consistently growing field. Not only will you broaden your understanding of the basic biology of disease processes, you'll also access updated treatment algorithms, information on techniques, and ...

Brain Tumors E Book

Brain Tumors E Book
  • Author : Andrew H. Kaye,Edward R. Laws Jr
  • Publisher : Elsevier Health Sciences
  • Release Date : 2011-12-06
  • Total pages : 1088
  • ISBN : 9780128215845
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Summary : Meet the increasing need for effective brain tumor management with the highly anticipated revision of Brain Tumors by Drs. Andrew H. Kaye and Edward R. Laws. Over the past decade, enormous advances have been made in both the diagnosis and the surgical and radiotherapeutic management of brain tumors. This new ...

Gunderson Tepper s Clinical Radiation Oncology E Book

Gunderson   Tepper   s Clinical Radiation Oncology  E Book
  • Author : Joel E. Tepper
  • Publisher : Elsevier Health Sciences
  • Release Date : 2019-12-06
  • Total pages : 1648
  • ISBN : 9780128215845
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Summary : A comprehensive, multidisciplinary resource for the entire radiation oncology team, Gunderson & Tepper’s Clinical Radiation Oncology, 5th Edition, thoroughly covers all aspects of this complex and dynamic field. Concise, templated chapters cover the basic biology of oncologic disease processes as well as updated treatment algorithms, the latest clinical guidelines, and ...

Radiation Oncology E Book

Radiation Oncology E Book
  • Author : James D. Cox,Kie Kian Ang
  • Publisher : Elsevier Health Sciences
  • Release Date : 2009-10-29
  • Total pages : 1088
  • ISBN : 9780128215845
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Summary : Radiation Oncology: Rationale, Technique, Results, by James D. Cox, MD and K. Kian Ang, MD, PhD, provides you with authoritative guidance on the latest methods for using radiotherapy to treat patients with cancer. Progressing from fundamental principles through specific treatment strategies for the cancers of each organ system, it also ...

Molecular Pathomechanisms and New Trends in Drug Research

Molecular Pathomechanisms and New Trends in Drug Research
  • Author : Gyorgy Keri,Istvan Toth
  • Publisher : CRC Press
  • Release Date : 2002-11-14
  • Total pages : 664
  • ISBN : 9780128215845
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Summary : Knowledge of the basic mechanisms of human disease is essential for any student or professional engaged in drug research and development. Functional gene analysis (genomics), protein analysis (proteomics), and other molecular biological techniques have made it possible to understand these cellular processes, opening up exciting opportunities for no...

Antibody Mediated Drug Delivery Systems

Antibody Mediated Drug Delivery Systems
  • Author : Yashwant Pathak,Simon Benita
  • Publisher : John Wiley & Sons
  • Release Date : 2012-04-17
  • Total pages : 528
  • ISBN : 9780128215845
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Summary : This book covers various aspects of antibody mediated drug deliverysystems – theoretical aspects, processing, viral andnon-viral vectors, and fields where these systems find and /or arebeing evaluated for applications as therapeutics and diagnostictreatment. Chapters discuss actual applications of techniques usedfor formulation and characterization. Applications areas includecancer, pulmonary, ocular diseases; brain drug ...

Oncology of Infancy and Childhood E Book

Oncology of Infancy and Childhood E Book
  • Author : Stuart H. Orkin,David E. Fisher,A. Thomas Look,Samuel Lux,David Ginsburg,David G. Nathan
  • Publisher : Elsevier Health Sciences
  • Release Date : 2009-06-09
  • Total pages : 1392
  • ISBN : 9780128215845
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Summary : To address the growing complexities of childhood cancer, Nathan and Oski’s Hematology and Oncology of Infancy and Childhood has now been separated into two distinct volumes. With this volume devoted strictly to pediatric oncology, and another to pediatric hematology, you will be on the cutting edge of these two ...