NMR Metabolomics in Cancer Research

Written By Miroslava Čuperlović-Culf
NMR Metabolomics in Cancer Research
  • Publsiher : Elsevier
  • Release : 17 December 2012
  • ISBN : 1908818263
  • Pages : 446 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled NMR Metabolomics in Cancer Research written by Miroslava Čuperlović-Culf which was release on 17 December 2012, this book published by Elsevier. Available in PDF, EPUB and Kindle Format. Book excerpt: The application of nuclear magnetic resonance (NMR) metabolomics in cancer research requires an understanding of the many possibilities that NMR metabolomics can offer, as well as of the specific characteristics of the cancer metabolic phenotype and the open questions in cancer research. NMR metabolomics in cancer research presents a detailed account of the NMR spectroscopy methods applied to metabolomics mixture analysis along with a discussion of their advantages and disadvantages. Following an overview of the potential use of NMR metabolomics in cancer research, the book begins with an examination of the cancer metabolic phenotype and experimental methodology, before moving on to cover data pre-processing and data analysis. Chapters in the latter part of the book look at dynamic metabolic profiling, biomarker discovery, and the application of NMR metabolomics for different types of cancer, before a concluding chapter discusses future perspectives in the field. Focused description of NMR spectroscopy needed by cancer biologists who are starting to use metabolomics Current overview of knowledge related to the cancer metabolic phenotype from the perspective of metabolomics applications Information about the best practices in NMR metabolomics experimentation and data preprocessing as applied to different sample types

NMR Metabolomics in Cancer Research

NMR Metabolomics in Cancer Research
  • Author : Miroslava Čuperlović-Culf
  • Publisher : Elsevier
  • Release Date : 2012-12-17
  • Total pages : 446
  • ISBN : 1908818263
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Summary : The application of nuclear magnetic resonance (NMR) metabolomics in cancer research requires an understanding of the many possibilities that NMR metabolomics can offer, as well as of the specific characteristics of the cancer metabolic phenotype and the open questions in cancer research. NMR metabolomics in cancer research presents a detailed ...

Cancer Metabolomics

Cancer Metabolomics
  • Author : Shen Hu
  • Publisher : Springer Nature
  • Release Date : 2021-05-03
  • Total pages : 312
  • ISBN : 1908818263
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Summary : Cancer metabolomics is a rapidly evolving field that aims for a comprehensive dissection of the metabolic phenotypes and functional network of metabolites in human cancers. State of the art metabolomics tools have been developed and applied to studying cancer metabolism and developing metabolic targets for improved diagnosis, prognosis and therapeutic ...

Cancer Metabolomics 2018

Cancer Metabolomics 2018
  • Author : Paula Guedes De Pinho,Márcia Carvalho,Joana Pinto
  • Publisher : MDPI
  • Release Date : 2019-09-03
  • Total pages : 184
  • ISBN : 1908818263
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Summary : The metabolomics approach, defined as the study of all endogenously-produced low-molecular-weight compounds, appeared as a promising strategy to define new cancer biomarkers. Information obtained from metabolomic data can help to highlight disrupted cellular pathways and, consequently, contribute to the development of new-targeted therapies and the optimization of therapeutics. Therefore, metabolomic ...

Methodologies for Metabolomics

Methodologies for Metabolomics
  • Author : Norbert W. Lutz,Jonathan V. Sweedler,Ron A. Wevers
  • Publisher : Cambridge University Press
  • Release Date : 2013-01-21
  • Total pages : 627
  • ISBN : 1908818263
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Summary : Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range ...

Proteomic and Metabolomic Approaches to Biomarker Discovery

Proteomic and Metabolomic Approaches to Biomarker Discovery
  • Author : Haleem J. Issaq,Timothy D. Veenstra
  • Publisher : Academic Press
  • Release Date : 2019-10-24
  • Total pages : 504
  • ISBN : 1908818263
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Summary : Proteomic and Metabolomic Approaches to Biomarker Discovery, Second Edition covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods and presents a standard operating procedure for sample selection, preparation and storage, as well as data ...

NMR based Metabolomics

NMR based Metabolomics
  • Author : Hector C Keun
  • Publisher : Royal Society of Chemistry
  • Release Date : 2018-01-17
  • Total pages : 368
  • ISBN : 1908818263
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Summary : This book describes the state of the art in the application of NMR spectroscopy to metabolomics and will be a key title for researchers and practitioners....

An Omics Perspective on Cancer Research

An Omics Perspective on Cancer Research
  • Author : William C.S. Cho
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-04-07
  • Total pages : 269
  • ISBN : 1908818263
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Summary : Omics is an emerging and exciting area in the field of science and medicine. Numerous promising developments have been elucidated using omics (including genomics, transcriptomics, epigenomics, proteomics, metabolomics, interactomics, cytomics and bioinformatics) in cancer research. The development of high-throughput technologies that permit the solution of deciphering cancer from higher dimensionality ...

Applications of NMR Spectroscopy Vol 6

Applications of NMR Spectroscopy  Vol  6
  • Author : Atta-ur- Rahman,M. Iqbal Choudhary
  • Publisher : Bentham Science Publishers
  • Release Date : 2017-12-04
  • Total pages : 240
  • ISBN : 1908818263
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Summary : Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture. The sixth volume of the series features reviews focusing on NMR spectroscopic techniques for studying tautomerism, applications ...

Principles of Clinical Cancer Research

Principles of Clinical Cancer Research
  • Author : Loren K. Mell, MD,Phuoc T. Tran, MD, PhD,James B. Yu, MD, MHS,Qiang (Ed) Zhang, PhD
  • Publisher : Springer Publishing Company
  • Release Date : 2018-11-28
  • Total pages : 576
  • ISBN : 1908818263
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Summary : Principles of Clinical Cancer Research provides comprehensive coverage of the fundamentals of clinical cancer research, including the full spectrum of methodologies used in the field. For those involved in research or considering research careers, this book offers a mix of practical advice and analytical tools for effective training in theoretical ...

The Handbook of Metabonomics and Metabolomics

The Handbook of Metabonomics and Metabolomics
  • Author : John C. Lindon,Jeremy K. Nicholson,Elaine Holmes
  • Publisher : Elsevier
  • Release Date : 2011-08-11
  • Total pages : 572
  • ISBN : 1908818263
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Summary : Molecular biology operates at three levels – genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding ...

Metabolomics From Fundamentals to Clinical Applications

Metabolomics  From Fundamentals to Clinical Applications
  • Author : Alessandra Sussulini
  • Publisher : Springer
  • Release Date : 2017-01-28
  • Total pages : 350
  • ISBN : 1908818263
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Summary : This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine. It is the first volume to cover metabolomics clinical applications while also emphasizing analytical and statistical features. Moreover, future trends and perspectives in clinical metabolomics ...

Practical Applications of Computational Biology Bioinformatics 15th International Conference PACBB 2021

Practical Applications of Computational Biology   Bioinformatics  15th International Conference  PACBB 2021
  • Author : Miguel Rocha,Florentino Fdez-Riverola,Mohd Saberi Mohamad,Roberto Casado-Vara
  • Publisher : Springer Nature
  • Release Date : 2021-08-27
  • Total pages : 176
  • ISBN : 1908818263
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Summary : This book features novel research papers spanning many different subfields in bioinformatics and computational biology, presenting the latest research on the practical applications to promote fruitful interactions between young researchers in different areas related to the field. Clearly, biology is increasingly becoming a science of information, requiring tools from the ...

Applications of NMR Spectroscopy

Applications of NMR Spectroscopy
  • Author : Atta-ur-Rahman,M. Iqbal Choudhary
  • Publisher : Elsevier
  • Release Date : 2015-12-11
  • Total pages : 280
  • ISBN : 1908818263
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Summary : Applications of NMR Spectroscopy, Volume 3 presents the latest developments in the field of NMR spectroscopy, including the analysis of the structure-property relationship of polyphenols, breast cancer diagnosis, drug discovery and formulation, protein confirmation analysis using Fluorine NMR, and enaminone studies. The well-illustrated chapters contain comprehensive references to the recent literature. ...

Updates in Liver Cancer

Updates in Liver Cancer
  • Author : Hesham Abdeldayem
  • Publisher : BoD – Books on Demand
  • Release Date : 2017-04-05
  • Total pages : 222
  • ISBN : 1908818263
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Summary : Liver cancers result in considerable amount of financial and social burden. On the other hand, researches and clinical studies related to liver cancers continue to advance at a rapid pace. The chapters in this book provide state-of-the-art reviews on the current knowledge and advances in research and management of liver ...

Biomechanics of Cells and Tissues

Biomechanics of Cells and Tissues
  • Author : Paola Lecca
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-01-18
  • Total pages : 168
  • ISBN : 1908818263
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Summary : The application of methodological approaches and mathematical formalisms proper to Physics and Engineering to investigate and describe biological processes and design biological structures has led to the development of many disciplines in the context of computational biology and biotechnology. The best known applicative domain is tissue engineering and its branches. ...