New Combination Approaches to Enhance Rituximab Based Lymphoma Therapies

Written By Anonim
New Combination Approaches to Enhance Rituximab Based Lymphoma Therapies
  • Publsiher : Academic Press
  • Release : 01 November 2020
  • ISBN : 0128167378
  • Pages : 250 pages
  • Rating : 4/5 from 21 reviews
GET THIS BOOKNew Combination Approaches to Enhance Rituximab Based Lymphoma Therapies


Read or download book entitled New Combination Approaches to Enhance Rituximab Based Lymphoma Therapies written by Anonim which was release on 01 November 2020, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: New Combination Approaches to Enhance Rituximab-Based Lymphoma Therapies provides general updated information on the resistance of various human lymphoma/leukemia subtypes to anti-CD20 therapeutic antibodies. It discusses also the description of various targeted sensitizing agents that can reverse innate or acquired resistance when used in combination with various FDA-approved anti-CD20 antibodies. There have been a lot of reports in which the treatment with anti-CD20 antibodies for various lymphomas/leukemias has resulted in significant clinical responses; however, there have been also subsets of cancer patients who did not respond initially and several of the responding patients developed resistance to subsequent treatments with the same or different regimens. Therefore, the use of various immunosensitizing agents targeting resistant factors to reverse resistance has been considered and this book discusses each of them in depth, such as Bortexomib, Immunomodulation Agents, Obinutuzumab, Tumor Suppressors, and HDAC Inhibitors. This book is a valuable source for cancer researchers, oncologists, pharmacologists and different members of biomedical field interested in fighting cancer resistance to anti-CD20 antibodies. Provides a general overview of various sensitizing agents that can work effectively when used in combination with anti-CD20 antibodies to reverse resistance Offers potential underlying mechanisms by which the cancer cells are either inherently resistant or become unresponsive to further antibody treatments Discusses how to develop new targeted agents to underlie resistance in order to expand research on this field

New Combination Approaches to Enhance Rituximab Based Lymphoma Therapies

New Combination Approaches to Enhance Rituximab Based Lymphoma Therapies
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2020-11-01
  • Total pages : 250
  • ISBN : 0128167378
GET BOOK

Summary : New Combination Approaches to Enhance Rituximab-Based Lymphoma Therapies provides general updated information on the resistance of various human lymphoma/leukemia subtypes to anti-CD20 therapeutic antibodies. It discusses also the description of various targeted sensitizing agents that can reverse innate or acquired resistance when used in combination with various FDA-approved anti-CD20 ...

Resistance to Targeted Therapies in Lymphomas

Resistance to Targeted Therapies in Lymphomas
  • Author : Ana C. Xavier,Mitchell S. Cairo
  • Publisher : Springer Nature
  • Release Date : 2019-09-13
  • Total pages : 210
  • ISBN : 0128167378
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Summary : Over the past few decades, lymphoma patient outcomes have improved as a result of multidrug chemotherapy and radiation therapy, intensification of treatment, improvement in supportive care, and better imaging and staging systems. Even more recently, there has been tremendous progress in the understanding of cancer cell biology and its microenvironment ...

The Lymphoid Neoplasms 3ed

The Lymphoid Neoplasms 3ed
  • Author : Ian Magrath
  • Publisher : CRC Press
  • Release Date : 2010-07-30
  • Total pages : 1689
  • ISBN : 0128167378
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Summary : This comprehensive and authoritative reference covers all aspects of the group of disorders collectively known as the lymphoid neoplasms. The reader is taken through a description of its normal cellular origins and the molecular genetic abnormalities that can lead to this group of conditions, a section of the book that ...

Living with Lymphoma

Living with Lymphoma
  • Author : Elizabeth M. Adler
  • Publisher : JHU Press
  • Release Date : 2005-09-30
  • Total pages : 399
  • ISBN : 0128167378
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Summary : When neurobiologist Elizabeth M. Adler was diagnosed with non-Hodgkin's lymphoma, she learned everything she could about the disease. In "Living with Lymphoma," she combines her knowledge of lymphoma--both scientific and personal--with the desire to help other patients come to grips with this complex, and often baffling, disease. Readers gain sufficient ...

Perry s The Chemotherapy Source Book

Perry s The Chemotherapy Source Book
  • Author : Michael C. Perry,Donald C. Doll,Carl E. Freter
  • Publisher : Lippincott Williams & Wilkins
  • Release Date : 2012-07-30
  • Total pages : 848
  • ISBN : 0128167378
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Summary : Perry’s The Chemotherapy Source Book, now in its fifth edition, provides information on the choice of chemotherapeutic agents, the use of combination chemotherapy, and the toxicity of individual drugs. Organized by site, this is the only book of its kind to focus strictly on the clinical practice of chemotherapy, ...

Goldman s Cecil Medicine Expert Consult Premium Edition Enhanced Online Features and Print Single Volume 24

Goldman s Cecil Medicine Expert Consult Premium Edition    Enhanced Online Features and Print  Single Volume 24
  • Author : Russell La Fayette Cecil,Lee Goldman,Andrew I. Schafer
  • Publisher : Elsevier Health Sciences
  • Release Date : 2012-01-01
  • Total pages : 2655
  • ISBN : 0128167378
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Summary : Since 1927, Goldman-Cecil Medicine has been the world's most influential internal medicine resource. In the ground-breaking 25th edition, your original purchase ensures you will be up-to-date without the need for a subscription. Through the new, more powerful Expert Consult eBook platform, this "living text" provides continuous updates that will integrate the ...

Principles of Cancer Biotherapy

Principles of Cancer Biotherapy
  • Author : Robert K. Oldham,Robert O. Dillman
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-08-29
  • Total pages : 742
  • ISBN : 0128167378
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Summary : At the time of the first edition of Principles of Cancer Biotherapy in 1987, this book represented the first comprehensive textbook on biological therapy. In 1991, when the second edition was published, there was still some doubt on the part of many oncologists and cancer researchers as to the therapeutic value of ...

Non Hodgkin Lymphoma

Non Hodgkin Lymphoma
  • Author : Andrew M. Evens,Kristie A. Blum
  • Publisher : Springer
  • Release Date : 2015-02-06
  • Total pages : 344
  • ISBN : 0128167378
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Summary : This book provides clinical practitioners and the research community with detailed information on the diagnosis, prognosis, and treatment of non-Hodgkin lymphoma, taking into account the significant growth in knowledge including multiple therapeutic advances that have been achieved over the past 5-10 years. The work is subdivided into epidemiology, pathogenesis, pathology, ...

Drug Benefits and Risks

Drug Benefits and Risks
  • Author : C.J. van Boxtel,B. Santoso,I.R. Edwards
  • Publisher : IOS Press
  • Release Date : 2008-08-06
  • Total pages : 848
  • ISBN : 0128167378
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Summary : This updated and revised 2nd edition of Drug Benefits and Risks is an inclusive reference exploring the scientific basis and practice of drug therapy. The key concept is to look at the balance between the benefits and risks of drugs, but in this context also highlighting the social impact which ...

Combinatorial Approaches to Enhance Anti Tumor Immunity Focus on Immune Checkpoint Blockade Therapy

Combinatorial Approaches to Enhance Anti Tumor Immunity  Focus on Immune Checkpoint Blockade Therapy
  • Author : Patrik Andersson,Christian Ostheimer
  • Publisher : Frontiers Media SA
  • Release Date : 2019-12-27
  • Total pages : 212
  • ISBN : 0128167378
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Summary : The immune system harbors great potential for controlling and eliminating tumors. Recent developments in the field of immuno-oncology has led to unprecedented clinical benefits for a broad spectrum of solid tumors. However, immunotherapy (IT) approaches currently have several limitations including (i) low response rate; (ii) development of resistance and (iii) ...

Methods of Cancer Diagnosis Therapy and Prognosis

Methods of Cancer Diagnosis  Therapy  and Prognosis
  • Author : M. A. Hayat
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-04-07
  • Total pages : 476
  • ISBN : 0128167378
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Summary : There are more than 100 types of cancers In Part II, head and neck cancer is d- affecting all parts of the human body. cussed. The global number of annual new More than 11 million people are diagnosed cases of this malignancy is ~500,000. These with cancer every year, and it is estimated ...

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  • Author : Peter H. Wiernik,John M. Goldman,Janice P. Dutcher,Robert A. Kyle
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-09-22
  • Total pages : 1431
  • ISBN : 0128167378
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Summary : Neoplastic Diseases of the Blood integrates the history, epidemiology, pathology, pathophysiology, and therapeutics of modern neoplastic hematopathology. The book is divided into five major sections, with the first four covering the spectrum of hematologic neoplasia— Chronic Leukemias and Related Disorders , Acute Leukemias, Myeloma and Related Disorders, and Lymphomas. The fifth ...

Antibody Fc

Antibody Fc
  • Author : George J. Weiner
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-08-06
  • Total pages : 358
  • ISBN : 0128167378
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Summary : Monoclonal antibodies (mAbs), including rituximab, are now a mainstay in the therapy of cancer. Despite their undeniable therapeutic value, there is much we do not fully understand about the mechanisms of action responsible for their anti-tumor effects. These mechanisms are often studied in isolation. In this chapter, we will review ...

Cancer Immunology

Cancer Immunology
  • Author : Nima Rezaei
  • Publisher : Springer
  • Release Date : 2014-12-29
  • Total pages : 485
  • ISBN : 0128167378
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Summary : This translational book describes in detail the clinical application of novel approaches in cancer immunotherapy with the aim of educating clinicians in the implications of the most recent research and new developments in the field. The scope is broad, encompassing, for example, prognostic biomarkers for personalized cancer treatment, strategies for ...

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  • Author : Manfred Dietel
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-06-10
  • Total pages : 262
  • ISBN : 0128167378
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Summary : From its introduction, oncological chemotherapy has been encumbered by poor selectivity because antiproliferative drugs are often toxic not only to tumor cells but also to important populations of the body’s non-neoplastic cells. Modern targeted therapies interact with defined molecules present on cancer cells, adding increased selectivity to their toxic ...