Neuronal Chloride Transporters in Health and Disease

Written By Xin Tang
Neuronal Chloride Transporters in Health and Disease
  • Publsiher : Academic Press
  • Release : 19 June 2020
  • ISBN : 0128153199
  • Pages : 766 pages
  • Rating : 4/5 from 21 reviews
GET THIS BOOKNeuronal Chloride Transporters in Health and Disease


Read or download book entitled Neuronal Chloride Transporters in Health and Disease written by Xin Tang which was release on 19 June 2020, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: In the past several years, there has been an exciting body of new research that links impairments in the expression or function of neuronal chloride transporters to a growing number of diseases spanning from autism to brain aging. This book introduces the core concepts and highlights the recent advances in understanding the physiology and pathophysiology of the KCC and NKCC families of neuronal chloride transporters. Neuronal chloride transporter biology is reviewed, including roles in setting the transmembrane chloride gradient and the chloride transport-independent functions, such as regulating excitatory neurotransmission. Chapters are also dedicated to addressing the structure, post-translational modification, membrane trafficking, and protein interaction partners of neuronal chloride transporters, as well as the genetic and environmental factors that regulate their expression in neurons and the novel therapeutic approaches that target neuronal chloride transporters to treat neurological diseases. This new volume will provide readers with an up-to-date summary of the recent advances in neuronal chloride transporter research, with particular emphasis on some of the key emerging topics in the field. Summarizes roles of KCCs and NKCCs in regulating inhibitory and excitatory neurotransmission Reviews the molecular and cellular biology of neuronal chloride transporters Links neuronal chloride transporter deficiencies to autism, epilepsy, depression, and more Identifies role of transporter deficiencies in pain as well as brain and spinal cord injury Discusses drug research targeting neuronal chloride transporters for nervous system diseases

Neuronal Chloride Transporters in Health and Disease

Neuronal Chloride Transporters in Health and Disease
  • Author : Xin Tang
  • Publisher : Academic Press
  • Release Date : 2020-06-19
  • Total pages : 766
  • ISBN : 0128153199
GET BOOK

Summary : In the past several years, there has been an exciting body of new research that links impairments in the expression or function of neuronal chloride transporters to a growing number of diseases spanning from autism to brain aging. This book introduces the core concepts and highlights the recent advances in ...

Epithelial Anion Transport in Health and Disease

Epithelial Anion Transport in Health and Disease
  • Author : Derek J. Chadwick,Jamie A. Goode
  • Publisher : John Wiley & Sons
  • Release Date : 2006-07-11
  • Total pages : 284
  • ISBN : 0128153199
GET BOOK

Summary : Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, but a breakthrough occurred with the discovery of the SLC26 transporters family. It is now clear that the SLC26 transporters have broad physiological functions ...

Ion Channels in Health and Disease

Ion Channels in Health and Disease
  • Author : Geoffrey S. Pitt
  • Publisher : Academic Press
  • Release Date : 2016-10-04
  • Total pages : 392
  • ISBN : 0128153199
GET BOOK

Summary : Ion Channels in Health and Disease provides key insight to allow researchers to generate discoveries across disease states. A single resource that integrates disparate areas of biology and disease ion channel biology, this publication includes cross-referencing for disease, channels, and tissues. Offers a broad view of research of interest to ...

GABA signaling in health and disease

GABA signaling in health and disease
  • Author : Yehezkel Ben-Ari
  • Publisher : Frontiers E-books
  • Release Date : 2021-12-05
  • Total pages : 212
  • ISBN : 0128153199
GET BOOK

Summary : GABAergic neurons provide most of the inhibitory drive of adult networks and play major roles in the integrative properties of brain networks. Alterations of GABAergic signals are associated with major neurological disorders and GABA mimetic drugs are widely used as comfort molecules and to treat several brain disorders. Thus, the ...

Intestinal Water and Electrolyte Transport in Health and Disease

Intestinal Water and Electrolyte Transport in Health and Disease
  • Author : Mrinalin Rao,Jayashree Sarathy
  • Publisher : Biota Publishing
  • Release Date : 2012-01-12
  • Total pages : 105
  • ISBN : 0128153199
GET BOOK

Summary : The unique architecture and physiology of the mammalian intestine, together with a tightly coordinated regulatory system, allows for the handling and absorption of as much as 9 L of fluid a day with 98% or greater efficiency. Advances in the past 40 years have made inroads into revealing the intricacies and interplay of ...

Retinal Pigment Epithelium in Health and Disease

Retinal Pigment Epithelium in Health and Disease
  • Author : Alexa Karina Klettner,Stefan Dithmar
  • Publisher : Springer Nature
  • Release Date : 2020-01-01
  • Total pages : 357
  • ISBN : 0128153199
GET BOOK

Summary : This book provides a contemporary resource on one of the major players in retinal diseases – the Retinal Pigment Epithelium (RPE). Throughout the book, the physiological and the pathological function of the RPE are covered on equal terms, to help readers to understand the RPE as a whole. Moreover, the development ...

The Blood Brain Barrier in Health and Disease Volume One

The Blood Brain Barrier in Health and Disease  Volume One
  • Author : Katerina Dorovini-Zis
  • Publisher : CRC Press
  • Release Date : 2015-06-23
  • Total pages : 426
  • ISBN : 0128153199
GET BOOK

Summary : Located at the interface between blood and the brain, the blood-brain barrier is a dynamic permeability barrier formed by a continuous layer of specialized endothelial cells endowed with important permeability, transport, and regulatory functions that both protect the internal milieu of the brain and allow essential nutrients to be transported ...

Biomedical Index to PHS supported Research

Biomedical Index to PHS supported Research
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1994
  • Total pages : 212
  • ISBN : 0128153199
GET BOOK

Summary : Download or read online Biomedical Index to PHS supported Research written by , published by which was released on 1994. Get Biomedical Index to PHS supported Research Books now! Available in PDF, ePub and Kindle....

Biomedical Index to PHS supported Research pt A Subject access A H

Biomedical Index to PHS supported Research  pt  A  Subject access A H
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1993
  • Total pages : 212
  • ISBN : 0128153199
GET BOOK

Summary : Download or read online Biomedical Index to PHS supported Research pt A Subject access A H written by , published by which was released on 1993. Get Biomedical Index to PHS supported Research pt A Subject access A H Books now! Available in PDF, ePub and Kindle....

Cell Physiology Sourcebook

Cell Physiology Sourcebook
  • Author : Nicholas Sperelakis
  • Publisher : Academic Press
  • Release Date : 2012-01
  • Total pages : 970
  • ISBN : 0128153199
GET BOOK

Summary : This authoritative book gathers together a broad range of ideas and topics that define the field. It provides clear, concise, and comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics. The Fourth Edition contains substantial new material. Most chapters have been thoroughly reworked. The ...

Physiology and Pathology of Chloride Transporters and Channels in the Nervous System

Physiology and Pathology of Chloride Transporters and Channels in the Nervous System
  • Author : F. Javier Alvarez-Leefmans,Eric Delpire
  • Publisher : Academic Press
  • Release Date : 2009-08-22
  • Total pages : 630
  • ISBN : 0128153199
GET BOOK

Summary : The importance of chloride ions in cell physiology has not been fully recognized until recently, in spite of the fact that chloride (Cl-), together with bicarbonate, is the most abundant free anion in animal cells, and performs or determines fundamental biological functions in all tissues. For many years it was ...

Epilepsy and Neurodevelopmental Diseases

Epilepsy and Neurodevelopmental Diseases
  • Author : Eleonora Palma,Eleonora Aronica,Erwin van Vliet
  • Publisher : Frontiers Media SA
  • Release Date : 2020-12-09
  • Total pages : 212
  • ISBN : 0128153199
GET BOOK

Summary : Download or read online Epilepsy and Neurodevelopmental Diseases written by Eleonora Palma,Eleonora Aronica,Erwin van Vliet, published by Frontiers Media SA which was released on 2020-12-09. Get Epilepsy and Neurodevelopmental Diseases Books now! Available in PDF, ePub and Kindle....

Research Awards Index

Research Awards Index
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1987
  • Total pages : 212
  • ISBN : 0128153199
GET BOOK

Summary : Download or read online Research Awards Index written by , published by which was released on 1987. Get Research Awards Index Books now! Available in PDF, ePub and Kindle....

Ion and Water Transport in Cell Death

Ion and Water Transport in Cell Death
  • Author : Markus Ritter,Yasunobu Okada,Alexander A. Mongin,Giovanna Valenti
  • Publisher : Frontiers Media SA
  • Release Date : 2021-10-25
  • Total pages : 212
  • ISBN : 0128153199
GET BOOK

Summary : Download or read online Ion and Water Transport in Cell Death written by Markus Ritter,Yasunobu Okada,Alexander A. Mongin,Giovanna Valenti, published by Frontiers Media SA which was released on 2021-10-25. Get Ion and Water Transport in Cell Death Books now! Available in PDF, ePub and Kindle....

Nonclassical Ion Channels in the Nervous System

Nonclassical Ion Channels in the Nervous System
  • Author : Xu Tian-le,Long-Jun Wu
  • Publisher : CRC Press
  • Release Date : 2021-08-05
  • Total pages : 427
  • ISBN : 0128153199
GET BOOK

Summary : Ion channels generate bioelectricity. Recent findings have documented the biophysical properties, the structure, assembly and regulation, and function and dysfunction of nonclassical nervous system ion channels. This book reviews nonclassical ion channel research, ranging from the basic biology, structure, regulations to their functions not only in normal physiology but also ...