Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability

Written By Carlo Sala
Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability
  • Publsiher : Academic Press
  • Release : 30 April 2016
  • ISBN : 0128005335
  • Pages : 394 pages
  • Rating : 4/5 from 21 reviews
GET THIS BOOKNeuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability


Read or download book entitled Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability written by Carlo Sala which was release on 30 April 2016, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings. In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders. Despite the prevalence and insidious nature of this disorder, this book remains to be an extensive resource of information and background on the state of current research in the field. The book serves as a reference for this purpose, and discusses the crucial role synaptic activity plays in proper brain function. In addition, the volume discusses the neurodevelopmental synaptopathies and serves as a resource for scientists and clinicians in all biomedical science specialties. This research has been crucial for recent studies that have provided a rationale for the development of pharmacological agents able to counteract functional synaptic anomalies and potentially ameliorate some ASD symptoms. Introduces the genetic and non-genetic causes of autism and associated intellectual disabilities Describes the genes implicated in autistic spectrum disorders and their function Considers major individual genetic causes of autism, Rett syndrome, Fragile X syndrome, and other autism spectrum disorders, as well as their classification as synaptopathies Presents a thorough discussion of the clinical aspects of multiple neurodevelopmental disorders and the experimental models that exist to study their pathophysiology in vitro and in vivo, including animal models and patient-derived stem cell culture

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability
  • Author : Carlo Sala,Chiara Verpelli
  • Publisher : Academic Press
  • Release Date : 2016-04-30
  • Total pages : 394
  • ISBN : 0128005335
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Summary : Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings. In addition, three quarters of ASD patients also manifest ...

Shankopathies Shank Protein Deficiency Induced Synaptic Diseases

Shankopathies  Shank Protein Deficiency Induced Synaptic Diseases
  • Author : Elodie Ey,Thomas Bourgeron,Tobias Maria Boeckers,Eunjoon Kim,Kihoon Han
  • Publisher : Frontiers Media SA
  • Release Date : 2020-03-10
  • Total pages : 212
  • ISBN : 0128005335
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Summary : Download or read online Shankopathies Shank Protein Deficiency Induced Synaptic Diseases written by Elodie Ey,Thomas Bourgeron,Tobias Maria Boeckers,Eunjoon Kim,Kihoon Han, published by Frontiers Media SA which was released on 2020-03-10. Get Shankopathies Shank Protein Deficiency Induced Synaptic Diseases Books now! Available in PDF, ePub and ...

Neuronal Stress Pathways Influence Synaptic Development and Nervous System Function in Drosophila Melanogaster

Neuronal Stress Pathways Influence Synaptic Development and Nervous System Function in Drosophila Melanogaster
  • Author : Alexandra Russo
  • Publisher : Unknown
  • Release Date : 2019
  • Total pages : 122
  • ISBN : 0128005335
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Summary : Synaptic development is a complex and highly orchestrated process in which the nervous system must build appropriately sized and sufficiently strong connections between neurons and their targets. Many neurodevelopmental disorders are caused by dysregulation of the mechanisms that promote the formation of normal synaptic connections. Here, I show that dysregulation ...

Autism

Autism
  • Author : Michael Fitzgerald,Jane Yip
  • Publisher : BoD – Books on Demand
  • Release Date : 2017-04-12
  • Total pages : 344
  • ISBN : 0128005335
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Summary : This book opens with a discussion of neurodiversity and an elaboration of the diagnosis of autism. It then examines factors correlating with autism, including sex bias, month of birth, migration and impact of infant feeding. The next section is on the impact of autism. The neurobiology and genetic section deals ...

Autism Spectrum Disorders Developmental Trajectories Neurobiological Basis Treatment Update Volume 2

Autism Spectrum Disorders  Developmental Trajectories  Neurobiological Basis  Treatment Update Volume 2
  • Author : Roberto Canitano,Yuri Bozzi,Dirk Dhossche
  • Publisher : Frontiers Media SA
  • Release Date : 2020-07-03
  • Total pages : 212
  • ISBN : 0128005335
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Summary : Download or read online Autism Spectrum Disorders Developmental Trajectories Neurobiological Basis Treatment Update Volume 2 written by Roberto Canitano,Yuri Bozzi,Dirk Dhossche, published by Frontiers Media SA which was released on 2020-07-03. Get Autism Spectrum Disorders Developmental Trajectories Neurobiological Basis Treatment Update Volume 2 Books now! Available in PDF, ePub ...

Autism Spectrum Disorders From Genotypes to Phenotypes

Autism Spectrum Disorders  From Genotypes to Phenotypes
  • Author : Valsamma Eapen,Andrew J. Whitehouse,Charles Claudianos,Rudi Crncec
  • Publisher : Frontiers Media SA
  • Release Date : 2015-12-10
  • Total pages : 212
  • ISBN : 0128005335
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Summary : This Research Topic covers the pathogenetic processes in Autism Spectrum Disorder (ASD) that underpin the translation of genetic vulnerability to clinically significant symptoms. Available research data in ASD suggests that it is a neural connectivity disorder and that the social communication and related neurobehavioural symptoms result from reduced synchronization between ...

Cassidy and Allanson s Management of Genetic Syndromes

Cassidy and Allanson s Management of Genetic Syndromes
  • Author : John C. Carey,Suzanne B. Cassidy,Agatino Battaglia,David Viskochil
  • Publisher : John Wiley & Sons
  • Release Date : 2021-01-27
  • Total pages : 1104
  • ISBN : 0128005335
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Summary : The most recent update to one of the most essential references on medical genetics Cassidy and Allanson's Management of Genetic Syndromes, 4th Edition is the latest version of a classic text in medical genetics. With newly covered disorders and cutting-edge, up-to-date information, this resource remains the most crucial reference on ...

Neural and Synaptic Defects in Autism Spectrum Disorders

Neural and Synaptic Defects in Autism Spectrum Disorders
  • Author : Hansen Wang,Laurie C. Doering
  • Publisher : Frontiers Media SA
  • Release Date : 2015-07-07
  • Total pages : 212
  • ISBN : 0128005335
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Summary : Autism spectrum disorders (ASDs) are a group of genetically and clinically heterogeneous neurodevelopmental disorders characterized by impaired reciprocal social interactions and communication, and restricted and repetitive patterns of behaviors and interests. Studies in genetics, neurobiology and systems biology are providing insights into the pathogenesis of ASDs. Investigation of neural and ...

Biometals in Autism Spectrum Disorders

Biometals in Autism Spectrum Disorders
  • Author : Andreas Grabrucker
  • Publisher : Academic Press
  • Release Date : 2020-07-08
  • Total pages : 222
  • ISBN : 0128005335
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Summary : Biometals in Autism Spectrum Disorders will be the first to focus on trace metals and autism. Compared to other references examining ASDs or metallomics, a focused presentation of the findings of abnormal metal homeostasis in ASD has not yet come to be. This book provides for readers an overview of ...

A Time for Metabolism and Hormones

A Time for Metabolism and Hormones
  • Author : Paolo Sassone-Corsi,Yves Christen
  • Publisher : Springer
  • Release Date : 2016-04-04
  • Total pages : 132
  • ISBN : 0128005335
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Summary : Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of ...

Charney Nestler s Neurobiology of Mental Illness

Charney   Nestler s Neurobiology of Mental Illness
  • Author : Dennis S. Charney MD,Eric J. Nestler MD, PhD,Pamela Sklar MD, PhD,Joseph D. Buxbaum PhD
  • Publisher : Oxford University Press
  • Release Date : 2017-11-29
  • Total pages : 1008
  • ISBN : 0128005335
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Summary : In the years following publication of the DSM-5®, the field of psychiatry has seen vigorous debate between the DSM's more traditional, diagnosis-oriented approach and the NIMH's more biological, dimension-based RDoC (research domain criteria) approach. Charney & Nestler's Neurobiology of Mental Illness is an authoritative foundation for translating information from the laboratory ...

Ionotropic Glutamate Receptors Trafficking in Health and Disease

Ionotropic Glutamate Receptors Trafficking in Health and Disease
  • Author : Milos Petrovic,Maria Inmaculada Gonzalez-Gonzalez,Jeremy Henley
  • Publisher : Frontiers Media SA
  • Release Date : 2017-05-10
  • Total pages : 212
  • ISBN : 0128005335
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Summary : The knowledge about the properties and importance of ionotropic glutamate receptor trafficking is ever increasing. Importantly, the pace of the progress has been accelerated in recent years. Here, our contributors provide a) reviews on specific topics that present an up-to-date overview of the field, as well as b) original articles ...

Latest Findings in Intellectual and Developmental Disabilities Research

Latest Findings in Intellectual and Developmental Disabilities Research
  • Author : Uner Tan
  • Publisher : BoD – Books on Demand
  • Release Date : 2012-02-15
  • Total pages : 406
  • ISBN : 0128005335
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Summary : Intellectual and Developmental Disabilities presents reports on a wide range of areas in the field of neurological and intellectual disability, including habitual human quadrupedal locomotion with associated cognitive disabilities, Fragile X syndrome, autism spectrum disorders, Down syndrome, and intellectual developmental disability among children in an African setting. Studies are presented ...

Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management

Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management
  • Author : M. Mohamed Essa,M. Walid Qoronfleh
  • Publisher : Springer Nature
  • Release Date : 2020-01-31
  • Total pages : 693
  • ISBN : 0128005335
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Summary : The book focuses on implications of traditional and processed foods for autism spectrum disorder (ASD) intervention and management. Numerous phytonutrients and pharmacologically active compounds in edible natural products and diet could influence and offer protection to neuronal dysfunction that occurs due to ASD. The neuroprotective effects of various fruits, vegetables, ...

Autism Spectrum Disorders Developmental Trajectories Neurobiological Basis Treatment Update

Autism Spectrum Disorders  Developmental Trajectories  Neurobiological Basis  Treatment Update
  • Author : Roberto Canitano,Yuri Bozzi
  • Publisher : Frontiers Media SA
  • Release Date : 2017-08-30
  • Total pages : 212
  • ISBN : 0128005335
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Summary : This Research Topic has the aim to fill the gap of the many unresolved scientific issues on Autism Spectrum Disorders (ASD) that are still in need of investigation, Targeted treatments based on the understanding of the underlying pathogenic mechanisms of disease are still lacking. Further research is awaited and should ...