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- Author : Pamela A. Kozlowski
- Publsiher : Springer Science & Business Media
- Release : 11 January 2012
- ISBN : 3642236936
- Pages : 198 pages
- Rating : 4/5 from 21 reviews
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Read or download book entitled Mucosal Vaccines written by Pamela A. Kozlowski which was release on 11 January 2012, this book published by Springer Science & Business Media. Available in PDF, EPUB and Kindle Format. Book excerpt: This volume is focused on the development of vaccines which generate immune effectors capable of blocking mucosal entry or peripheral pathogen spread. A critical first step in the design of mucosal vaccines is the selection of administration route. Not all mucosal immunization routes are created equally when it comes to eliciting immune responses in multiple body compartments. This subject and situations when a mucosal route may not be required for vaccine delivery are reviewed here with an emphasis on the sublingual immunization route, which may offer a safer alternative to the nasal route for induction of broadly disseminated immune responses. External host defenses that inhibit entry of microorganisms at mucosal surfaces also pose obstacles to the efficient internalization of mucosally-applied vaccines. Transcutaneous immunization with appropriate adjuvants and permeation enhancers can induce mucosal immune responses and may be advantageous for bypassing these luminal barriers. Other chapters describe strategies for enhancing uptake of mucosal vaccines, for instance through targeted delivery to antigen-sampling M cells, construction of virus-like particles which mimic natural pathogens, addition of mucoadhesives or formulation as nanoparticles. Topics include edible vaccines as well as plant-based production of subunit or particulate vaccines that could be administered by any route. Dry powder vaccines that could be insufflated or directly applied to mucosal surfaces may be particularly ideal for mass vaccination in developing countries. The manufacture, stability and efficacy of powder formulations is comprehensively reviewed. We conclude with chapters on two of the greatest challenges facing mucosal vaccine development: human immunodeficiency virus and bioterrorist agents. This monograph highlights progress and information that should prove invaluable for the development of contemporary vaccines that prevent infection by these and other mucosal pathogens.
- Author : Pamela A. Kozlowski
- Publisher : Springer Science & Business Media
- Release Date : 2012-01-11
- Total pages : 198
- ISBN : 3642236936
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Summary : This volume is focused on the development of vaccines which generate immune effectors capable of blocking mucosal entry or peripheral pathogen spread. A critical first step in the design of mucosal vaccines is the selection of administration route. Not all mucosal immunization routes are created equally when it comes to ...
- Author : Hiroshi Kiyono
- Publisher : Elsevier
- Release Date : 1996-10-23
- Total pages : 479
- ISBN : 3642236936
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Summary : This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, ...
- Author : David W. Pascual
- Publisher : Academic Press
- Release Date : 2019-10-19
- Total pages : 940
- ISBN : 3642236936
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Summary : Mucosal Vaccines: Innovation for Preventing Infectious Diseases discusses basic knowledge and discovery in the area of mucosal immunology and its related scientific fields. This completely updated, revised and authoritative treatise covers all aspects of mucosal vaccines, including their development, mechanisms of action, molecular/cellular aspects and practical applications. The book ...
- Author : Anonim
- Publisher : Unknown
- Release Date : 2000
- Total pages : 212
- ISBN : 3642236936
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Summary : Download or read online Emerging Infectious Diseases written by , published by which was released on 2000. Get Emerging Infectious Diseases Books now! Available in PDF, ePub and Kindle....
- Author : Dale L. (Dale Lawrence) Godson,Saskatchewan. Agriculture Development Fund,Veterinary Infectious Disease Organization
- Publisher : [Regina] : Agriculture Development Fund
- Release Date : 2001
- Total pages : 32
- ISBN : 3642236936
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Summary : Download or read online Using Interleukin 6 to Improve Mucosal Vaccines written by Dale L. (Dale Lawrence) Godson,Saskatchewan. Agriculture Development Fund,Veterinary Infectious Disease Organization, published by [Regina] : Agriculture Development Fund which was released on 2001. Get Using Interleukin 6 to Improve Mucosal Vaccines Books now! Available in PDF, ePub and Kindle....
- Author : Stanley A. Plotkin,Fred Brown,Florian Horaud
- Publisher : S Karger Ag
- Release Date : 1998
- Total pages : 280
- ISBN : 3642236936
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Summary : This publication covers all aspects of new vaccine development from the preclinical stage to licensing. It contains discussions about the preclinical testing which is necessary to obtain permission to test a new vaccine in clinical trials and to organize a clinical plan that will demonstrate the safety and efficacy of ...
- Author : European Commission. Directorate-General for Health and Consumer Protection
- Publisher : Unknown
- Release Date : 2008
- Total pages : 167
- ISBN : 3642236936
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Summary : Recoge : Basic vaccinology - Diseases specific vaccine research - Clinical research and capacity building....
- Author : Fred Brown,Lars R. Haaheim,Universitetet i Bergen
- Publisher : S Karger Ag
- Release Date : 1998
- Total pages : 372
- ISBN : 3642236936
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Summary : Leading specialists in the field present papers on a wide range of topics, including new adjuvants, mucosal immunity, new approaches to vaccine design, cytokines as immunomodulators, T-cell and B-cell responses, preclinical evaluation and in vivo models of immunity, and regulatory issues. Bringing the reader up to date on current trends ...
- Author : Anonim
- Publisher : Unknown
- Release Date : 2005
- Total pages : 212
- ISBN : 3642236936
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Summary : Download or read online ASM News written by , published by which was released on 2005. Get ASM News Books now! Available in PDF, ePub and Kindle....
- Author : Anonim
- Publisher : Unknown
- Release Date : 2002
- Total pages : 212
- ISBN : 3642236936
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Summary : Download or read online Chemical Abstracts written by , published by which was released on 2002. Get Chemical Abstracts Books now! Available in PDF, ePub and Kindle....
- Author : Anonim
- Publisher : Unknown
- Release Date : 2000
- Total pages : 212
- ISBN : 3642236936
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Summary : Download or read online Philosophical Transactions of the Royal Society of London written by , published by which was released on 2000. Get Philosophical Transactions of the Royal Society of London Books now! Available in PDF, ePub and Kindle....
- Author : Peggy O'Mara
- Publisher : Unknown
- Release Date : 1997
- Total pages : 313
- ISBN : 3642236936
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Summary : Download or read online Vaccination written by Peggy O'Mara, published by which was released on 1997. Get Vaccination Books now! Available in PDF, ePub and Kindle....
- Author : Derek T. O'Hagan
- Publisher : CRC PressI Llc
- Release Date : 1994-04-15
- Total pages : 268
- ISBN : 3642236936
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Summary : This one-of-a-kind book represents a timely and detailed assessment of the wide range of alternative "antigen carriers" that are currently being investigated as prospective delivery systems for the development of new and improved oral vaccines. Oral delivery remains the "ideal" approach to vaccination, both for economic reasons and for reasons ...
- Author : Renato Dulbecco
- Publisher : Unknown
- Release Date : 1997
- Total pages : 212
- ISBN : 3642236936
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Summary : Download or read online Encyclopedia of Human Biology written by Renato Dulbecco, published by which was released on 1997. Get Encyclopedia of Human Biology Books now! Available in PDF, ePub and Kindle....
- Author : Anonim
- Publisher : Unknown
- Release Date : 2007
- Total pages : 212
- ISBN : 3642236936
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Summary : Download or read online The Journal of Immunology written by , published by which was released on 2007. Get The Journal of Immunology Books now! Available in PDF, ePub and Kindle....
