Molecular Diagnostics and Treatment of Pancreatic Cancer

Written By Asfar Azmi
Molecular Diagnostics and Treatment of Pancreatic Cancer
  • Publsiher : Elsevier
  • Release : 14 April 2014
  • ISBN : 0124079466
  • Pages : 458 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Molecular Diagnostics and Treatment of Pancreatic Cancer written by Asfar Azmi which was release on 14 April 2014, this book published by Elsevier. Available in PDF, EPUB and Kindle Format. Book excerpt: Molecular Diagnostics and Treatment of Pancreatic Cancer describes the different emerging applications of systems biology and how it is shaping modern pancreatic cancer research. This book begins by introducing the current state of the art knowledge, trends in diagnostics, progress in disease model systems as well as new treatment and palliative care strategies in pancreatic cancer. Specific sections are dedicated to enlighten the readers to newer discoveries that have emerged from gene expression profiling, proteomics, metabolomics and systems level analyses of pancreatic cancer datasets. First of a kind and novel network strategies to understand oncogenic Kras signaling in pancreatic tumors are presented. The attempts to computationally model and prioritize microRNAs that cause pancreatic cancer resistance are also highlighted. Addressing this important area, Molecular Diagnostics and Treatment of Pancreatic Cancer provides insights into important network evaluation methodologies related to pancreatic cancer related microRNAs targetome. There are dedicated chapters on critical aspects of the evolving yet controversial field of pancreatic cancer stems cells. The work concludes by discussing the applications of network sciences in pancreatic cancer drug discovery and clinical trial design. Encompasses discussion of innovative tools including expression signatures in cell lines, 3D models, animal xenograft models, primary models and patient derived samples, aiding subversion of traditional biology paradigms, and enhancing comprehension across conventional length and temporal scales Coverage includes novel applications in targeted drugs, polypharmacology, network pharmacology and other related drug development arenas – helping researchers in pancreatic cancer drug discovery Summarizes many relevant computational and clinical references from fast-evolving literature Comprehensive glossary helps newer readers understand technical terms and specialized nomenclature

Molecular Diagnostics and Treatment of Pancreatic Cancer

Molecular Diagnostics and Treatment of Pancreatic Cancer
  • Author : Asfar Azmi
  • Publisher : Elsevier
  • Release Date : 2014-04-14
  • Total pages : 458
  • ISBN : 0124079466
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Summary : Molecular Diagnostics and Treatment of Pancreatic Cancer describes the different emerging applications of systems biology and how it is shaping modern pancreatic cancer research. This book begins by introducing the current state of the art knowledge, trends in diagnostics, progress in disease model systems as well as new treatment and ...

Molecular Diagnostics and Treatment of Pancreatic Cancer

Molecular Diagnostics and Treatment of Pancreatic Cancer
  • Author : Asfar Azmi
  • Publisher : Academic Press
  • Release Date : 2014-04-17
  • Total pages : 446
  • ISBN : 0124079466
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Summary : Molecular Diagnostics and Treatment of Pancreatic Cancer describes the different emerging applications of systems biology and how it is shaping modern pancreatic cancer research. This book begins by introducing the current state of the art knowledge, trends in diagnostics, progress in disease model systems as well as new treatment and ...

Principles of Molecular Diagnostics and Personalized Cancer Medicine

Principles of Molecular Diagnostics and Personalized Cancer Medicine
  • Author : Dongfeng Tan,Henry T. Lynch
  • Publisher : Lippincott Williams & Wilkins
  • Release Date : 2012-12-07
  • Total pages : 992
  • ISBN : 0124079466
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Summary : The role of molecular genetics in the treatment of malignancy continues to grow at an astonishing rate. Today’s subspecialized multidisciplinary approach to oncology has incorporated advances in targeted molecular therapy, prognosis, risk assessment, and prevention—all based at least in part on molecular diagnostics and imaging. Inside this cutting-edge ...

Pancreatic Cancer

Pancreatic Cancer
  • Author : Howard Reber
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Total pages : 347
  • ISBN : 0124079466
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Summary : A distinguished panel of world authorities reviews the current state of today's understanding, diagnosis, and treatment of pancreatic cancer. Their cutting-edge reviews discuss both medical and surgical modalities and include numerous insights into the basic molecular processes underlying the disease. Among the key topics covered are the prospects for early ...

Molecular Pathology and Diagnostics of Cancer

Molecular Pathology and Diagnostics of Cancer
  • Author : Domenico Coppola
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-11-29
  • Total pages : 601
  • ISBN : 0124079466
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Summary : Molecular pathology is based on the emergence of new techniques that greatly enhance the diagnostic accuracy when facing with challenging differential diagnoses. In addition, new molecular techniques are entering the clinical arena for their value in predicting therapy response and tumor prognosis. This book provides a guide for the practicing ...

Conquering RAS

Conquering RAS
  • Author : Asfar Azmi
  • Publisher : Academic Press
  • Release Date : 2016-08-11
  • Total pages : 294
  • ISBN : 0124079466
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Summary : Conquering RAS: From Biology to Cancer Therapy provides introductory knowledge on how modern RAS biology is taking shape in light of newer technological development. Each chapter is written in a manner that emphasizes simplicity and readability for both new investigators and established researchers. While RAS biology has been intensively studied ...

Animal Models in Cancer Drug Discovery

Animal Models in Cancer Drug Discovery
  • Author : Asfar Azmi,Ramzi M. Mohammad
  • Publisher : Academic Press
  • Release Date : 2019-04-16
  • Total pages : 470
  • ISBN : 0124079466
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Summary : Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on ...

Clinical Molecular Diagnostics

Clinical Molecular Diagnostics
  • Author : Shiyang Pan,Jinhai Tang
  • Publisher : Springer Nature
  • Release Date : 2021-07-08
  • Total pages : 889
  • ISBN : 0124079466
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Summary : This book covers the discovery of molecular biomarkers, the development of laboratory testing techniques and their clinical applications, focusing on basic research to clinical practice. It introduces new and crucial knowledge and ethics of clinical molecular diagnosis. This book emphasizes the applications of clinical molecular diagnostic test on health management, ...

Molecular Pathology An Update An Issue of the Clinics in Laboratory Medicine Ebook

Molecular Pathology  An Update  An Issue of the Clinics in Laboratory Medicine  Ebook
  • Author : Martin H. Bluth
  • Publisher : Elsevier Health Sciences
  • Release Date : 2018-05-23
  • Total pages : 249
  • ISBN : 0124079466
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Summary : This updated issue of Clinics in Laboratory Medicine, edited by Martin H. Bluth, will focus on Molecular Pathology. Topics include, but are not limited to, The Impact of Molecular Pathology on the Practice of Pathology; Molecular pathology techniques; Clinical Implication of MicroRNAs in Molecular Pathology; Diagnostic Molecular Microbiology; Molecular Pathology ...

Diagnostic Molecular Pathology

Diagnostic Molecular Pathology
  • Author : William B. Coleman,Gregory J. Tsongalis
  • Publisher : Academic Press
  • Release Date : 2016-10-05
  • Total pages : 582
  • ISBN : 0124079466
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Summary : Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies ...

Diagnostic Procedures in Pancreatic Disease

Diagnostic Procedures in Pancreatic Disease
  • Author : P. Malfertheiner,J.E. Dominguez-Munoz,H.-U. Schulz,Hans Lippert
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Total pages : 446
  • ISBN : 0124079466
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Summary : These proceedings of an international meeting held as recently as December 1996 cover diagnostic procedures in pancreatic disease, together with the progress made over the last 10 years in treating acute and chronic pancreatitis as well as pancreatic cancer. The meeting also covered standards in medical and surgical treatment....

Diseases of the Pancreas

Diseases of the Pancreas
  • Author : Hans Günther Beger,Seiki Matsuno,John L. Cameron
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-01-08
  • Total pages : 949
  • ISBN : 0124079466
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Summary : This book is based on the latest comprehensive data about molecular mechanism of acute pancreatitis, chronic pancreatitis and pancreatic cancer. The diagnostic techniques including histology, radiology, sonography etc. are based on the sensitivity and specificity of the respective methods. Special focus is given to the indication and contraindication to surgical ...

Cystic Tumors of the Pancreas

Cystic Tumors of the Pancreas
  • Author : Marco Del Chiaro,Stephan L. Haas,Richard D. Schulick
  • Publisher : Springer
  • Release Date : 2016-07-14
  • Total pages : 181
  • ISBN : 0124079466
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Summary : This book provides a detailed, up-to-date overview of cystic tumors of the pancreas, with coverage of all aspects of diagnosis and treatment (medical, endoscopic, and surgical). After opening chapters on pathology and classification, cytology, molecular biology, and epidemiology, the role of each of the relevant diagnostic methods is carefully examined. ...

Applications of Biotechnology in Oncology

Applications of Biotechnology in Oncology
  • Author : Kewal K. Jain
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-11-19
  • Total pages : 855
  • ISBN : 0124079466
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Summary : Applications of Biotechnology in Oncology collects key writings by Kewal K. Jain on the most important contributions of biotechnology to cancer research, particularly to the molecular diagnosis of cancer and drug delivery in cancer for personalized management of patients. Basics of various “omics” technologies and their application in oncology are ...

Theranostic Approach for Pancreatic Cancer

Theranostic Approach for Pancreatic Cancer
  • Author : Ganji Purnachandra Nagaraju,Sarfraz Ahmad
  • Publisher : Academic Press
  • Release Date : 2019-08-19
  • Total pages : 410
  • ISBN : 0124079466
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Summary : Theranostic Approach for Pancreatic Cancer modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property through introducing new strategies and drugs for tackling the disease. It brings information about ongoing research as well as clinical data about pancreatic cancer ...