Mitochondria in Obesity and Type 2 Diabetes

Written By Beatrice Morio
Mitochondria in Obesity and Type 2 Diabetes
  • Publsiher : Academic Press
  • Release : 15 April 2019
  • ISBN : 0128117524
  • Pages : 736 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Mitochondria in Obesity and Type 2 Diabetes written by Beatrice Morio which was release on 15 April 2019, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key concepts on topics such as the role of mitochondria in adipose tissue, cancer, cardiovascular comorbidities, skeletal muscle, the liver, kidney, and more. This book is a must-have reference for students and educational teams in biology, physiology and medicine, and researchers. Synthesizes actual knowledge on mitochondrial function Provides an integrated vision of each tissue in the etiology of obesity and type 2 diabetes Identifies the interactive networks that involve alteration in mitochondrial mass and function in disease progression Highlights the role played by mitochondria in the prevention and treatment of obesity and type 2 diabetes

Mitochondria in Obesity and Type 2 Diabetes

Mitochondria in Obesity and Type 2 Diabetes
  • Author : Beatrice Morio,Luc Penicaud,Michel Rigoulet
  • Publisher : Academic Press
  • Release Date : 2019-04-15
  • Total pages : 736
  • ISBN : 0128117524
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Summary : Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key ...

Targeting Mitochondrial Pathways in Obesity and Type 2 Diabetes

Targeting Mitochondrial Pathways in Obesity and Type 2 Diabetes
  • Author : Jessica Erin Sacks
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 204
  • ISBN : 0128117524
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Summary : Obesity is one of the largest medical epidemics our society faces today. There are over forty obesity-associated diseases that affect nearly every organ system in the body, including Type 2 Diabetes (T2D) and Non-Alcoholic Fatty Liver Disease (NAFLD). Insulin resistance is one of the hallmark characteristics underlying metabolic diseases, and ...

Mitochondria in Obesity and Type 2 Diabetes

Mitochondria in Obesity and Type 2 Diabetes
  • Author : Beatrice Morio,Luc Penicaud,Michel Rigoulet
  • Publisher : Academic Press
  • Release Date : 2019-04-13
  • Total pages : 459
  • ISBN : 0128117524
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Summary : Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key ...

Mechanisms Underlying Mitochondrial Function and Biogenesis

Mechanisms Underlying Mitochondrial Function and Biogenesis
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2013
  • Total pages : 72
  • ISBN : 0128117524
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Summary : Download or read online Mechanisms Underlying Mitochondrial Function and Biogenesis written by , published by which was released on 2013. Get Mechanisms Underlying Mitochondrial Function and Biogenesis Books now! Available in PDF, ePub and Kindle....

Bifurcation of in Vivo Hepatic Energy Metabolism and Glucose Production in Insulin Resistance and Diabetes

Bifurcation of in Vivo Hepatic Energy Metabolism and Glucose Production in Insulin Resistance and Diabetes
  • Author : Santhosh Satapati,University of Texas at Dallas. Graduate Program in Molecular and Cell Biology
  • Publisher : Unknown
  • Release Date : 2010
  • Total pages : 332
  • ISBN : 0128117524
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Summary : Obesity and type 2 diabetes are modern epidemics, closely associated with the development of insulin resistance. While lipid induced mitochondrial dysfunction plays an important role in skeletal muscle insulin resistance, it is unclear whether a similar etiology is responsible for hepatic insulin resistance. The purpose of this thesis is to investigate ...

Mitochondrial Oxidative Capacity In Human Skeletal Muscle Association with Plasma Lactate Concentration

Mitochondrial Oxidative Capacity In Human Skeletal Muscle  Association with Plasma Lactate Concentration
  • Author : Jessica Lynn Cook
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 87
  • ISBN : 0128117524
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Summary : ABSTRACT Background: Metabolic disease is a growing concern for public health. Obesity and Type II Diabetes are an epidemic and a phenotype for insulin resistance in human skeletal muscle. A reduced mitochondrial function and oxidative capacity may be associated with impairments in fatty acid oxidation, which can lead to insulin ...

Treatment of Type 2 Diabetes

Treatment of Type 2 Diabetes
  • Author : Colleen Croniger
  • Publisher : BoD – Books on Demand
  • Release Date : 2015-04-01
  • Total pages : 322
  • ISBN : 0128117524
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Summary : Obesity and type 2 diabetes are increasing worldwide problems. In this book we reviewed factors that contribute to glucose homeostasis and the pathogenesis of Type 2 diabetes. In addition the book addresses current strategies for treatment of Type 2 Diabetes....

Muscle Biopsy

Muscle Biopsy
  • Author : Challa Sundaram
  • Publisher : BoD – Books on Demand
  • Release Date : 2012-01-05
  • Total pages : 164
  • ISBN : 0128117524
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Summary : Investigation of muscle diseases has changed dramatically with the understanding of genetic basis of a wide range of muscle diseases. Muscle biopsy has become a powerful tool not only to provide diagnosis but to make tissue available for genetic studies and to basic scientists for biomedical research. Accurate interpretation of ...

Type 2 Diabetes

Type 2 Diabetes
  • Author : Kazuko Masuo
  • Publisher : BoD – Books on Demand
  • Release Date : 2013-06-26
  • Total pages : 546
  • ISBN : 0128117524
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Summary : Type 2 diabetes is now a global serious health problem. Patients with type 2 diabetes have 2-4 times higher risk of cardiovascular and renal complications, morbidity and mortality. This book, Type 2 Diabetes, is a unique book covering the topics including pathophysiology, complications and prevention and treatments. Understanding the etiology of the onset ...

Glucotoxicity mediated U03b2 Cell Dysfunction Related to ER mitochondria Ca2 Exchange and Mitochondria Fission in U03b2 Cells

Glucotoxicity mediated U03b2 Cell Dysfunction Related to ER mitochondria Ca2  Exchange and Mitochondria Fission in U03b2 Cells
  • Author : Anne-Marie Madec
  • Publisher : Unknown
  • Release Date : 2017
  • Total pages : 212
  • ISBN : 0128117524
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Summary : Beta cell dysfunction in type 2 diabetes (T2D) is associated with glucotoxicity-mediated alterations of both mitochondria and endoplasmic reticulum (ER). Both organelles interact at contact sites, defined as mitochondria-associated membranes (MAMs), and disruption of ER-mitochondria interactions was recently involved in hepatic (1) and muscle (2) insulin resistance and alterations of glucose homeostasis (3) ...

Increased Risk of Type 2 Diabetes in Patients with Mitochondrial Cytopathy and the Relationship with Obesity

Increased Risk of Type 2 Diabetes in Patients with Mitochondrial Cytopathy and the Relationship with Obesity
  • Author : Heathcliff Pierson D'Sa,Mark A. Tarnopolsky
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 196
  • ISBN : 0128117524
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Summary : Download or read online Increased Risk of Type 2 Diabetes in Patients with Mitochondrial Cytopathy and the Relationship with Obesity written by Heathcliff Pierson D'Sa,Mark A. Tarnopolsky, published by which was released on 2007. Get Increased Risk of Type 2 Diabetes in Patients with Mitochondrial Cytopathy and the Relationship with Obesity Books ...

Fatty Acid and Lipotoxicity in Obesity and Diabetes

Fatty Acid and Lipotoxicity in Obesity and Diabetes
  • Author : Gregory R. Bock,Jamie A. Goode
  • Publisher : John Wiley & Sons
  • Release Date : 2008-03-11
  • Total pages : 222
  • ISBN : 0128117524
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Summary : The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic β cell function, insulin secretion and lipid synthesis in the liver, and ...

Assessing the Mediating Effect of Obesity Linked SNPs in Nuclear Mitochondrial Genes on Exercise Enhanced Insulin Sensitivity

Assessing the Mediating Effect of Obesity Linked SNPs in Nuclear Mitochondrial Genes on Exercise Enhanced Insulin Sensitivity
  • Author : Kaitlin Erin Bessinger
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 38
  • ISBN : 0128117524
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Summary : Research shows that mitochondrial function and insulin resistance go hand in hand. As mitochondrial oxidative capacity is decreased, individuals are more likely to become insulin resistant and to develop type 2 diabetes. Exercise is known to increase mitochondrial oxidative capacity, helping these individuals enhance their insulin sensitivity. There are many genetic ...

Regulation of Mitochondria by Reversible Protein Phosphorylation

Regulation of Mitochondria by Reversible Protein Phosphorylation
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 174
  • ISBN : 0128117524
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Summary : Mitochondria are dynamic organelles that must rapidly adapt to changing cellular metabolic and biosynthetic demands. Until recently, mitochondria have represented an underappreciated site of regulation by reversible phosphorylation. Furthermore, the pathogenic alterations that underlie metabolic disorders have increasingly represented one of the principal challenges in cell biology. Our work has ...

Endoplasmic Reticulum Stress

Endoplasmic Reticulum Stress
  • Author : Cameron Wagner
  • Publisher : Nova Science Publishers
  • Release Date : 2016
  • Total pages : 153
  • ISBN : 0128117524
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Summary : This book provides current research on the regulation, function and role in health and disease of endoplasmic reticulum (ER) stress. The first chapter focuses on evidence that supports the role of endoplasmic reticulum stress, mitochondria-associated membranes (MAMs) microdomain and oxidative stress during obesity as a molecular pathway to type 2 diabetes ...