Mitochondria in Neurological Disorders

Written By Rajat Sandhir
Mitochondria in Neurological Disorders
  • Publsiher : Academic Press
  • Release : 15 November 2021
  • ISBN : 9780128217313
  • Pages : 500 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Mitochondria in Neurological Disorders written by Rajat Sandhir which was release on 15 November 2021, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Though mitochondria were traditionally thought to act only as cellular powerplants, it is clear today that they are central to various functions in nervous system like cell signaling, neurotransmission, synaptic plasticity, and glial cell functioning. Mitochondria in Neurological Diseases highlights various therapeutic approaches targeting mitochondria in neurological conditions. Focused on diverse neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, depression, and Amyotrophic lateral sclerosis, topics span basic mitochondrial physiology to mitochondrial dynamics and to the altered states of the nervous system. This book is appropriate for anyone interested in learning more about the physiological and pathophysiological functions of mitochondria in the nervous system. Up-to-date information on role of mitochondria in nervous system for graduate students and researchers Includes chapters on energy substrate utilization, calcium handling, mitochondria-organelle communication, and cell signaling Discusses recent techniques in understanding mitochondrial functions in nervous system Emphasizes the role of altered mitochondrial functions in various neurological conditions and their potential treatment strategies targeting mitochondria Chapters have references (key articles, books, protocols) for additional detailed study

Mitochondria in Neurological Disorders

Mitochondria in Neurological Disorders
  • Author : Rajat Sandhir
  • Publisher : Academic Press
  • Release Date : 2021-11-15
  • Total pages : 500
  • ISBN : 9780128217313
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Summary : Though mitochondria were traditionally thought to act only as cellular powerplants, it is clear today that they are central to various functions in nervous system like cell signaling, neurotransmission, synaptic plasticity, and glial cell functioning. Mitochondria in Neurological Diseases highlights various therapeutic approaches targeting mitochondria in neurological conditions. Focused on ...

Mitochondria and Brain Disorders

Mitochondria and Brain Disorders
  • Author : Stavros Baloyannis
  • Publisher : BoD – Books on Demand
  • Release Date : 2020-03-11
  • Total pages : 124
  • ISBN : 9780128217313
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Summary : The mitochondrion is a unique and ubiquitous organelle that contains its own genome, encoding essential proteins that are major components of the respiratory chain and energy production system. Mitochondria play a dominant role in the life and function of eukaryotic cells including neurons and glia, as their survival and activity ...

Role of Mitochondria in Neurological Disease

Role of Mitochondria in Neurological Disease
  • Author : Anthony S. Basile
  • Publisher : Unknown
  • Release Date : 2002
  • Total pages : 118
  • ISBN : 9780128217313
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Summary : Download or read online Role of Mitochondria in Neurological Disease written by Anthony S. Basile, published by which was released on 2002. Get Role of Mitochondria in Neurological Disease Books now! Available in PDF, ePub and Kindle....

Mitochondrial Dysfunction in Neurodegenerative Disorders

Mitochondrial Dysfunction in Neurodegenerative Disorders
  • Author : Amy K. Reeve,Eve M. Simcox,Michael R. Duchen,Doug M. Turnbull
  • Publisher : Springer
  • Release Date : 2016-06-08
  • Total pages : 380
  • ISBN : 9780128217313
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Summary : This second edition brings together up-to-date contributions from leaders in the field internationally on the various ways in which mitochondrial dysfunction contributes to the pathogenesis of neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease and multiple sclerosis. The reader is guided through the basic functions of mitochondria and the ...

Diagnosis and Management of Mitochondrial Disorders

Diagnosis and Management of Mitochondrial Disorders
  • Author : Michelangelo Mancuso,Thomas Klopstock
  • Publisher : Springer
  • Release Date : 2019-03-30
  • Total pages : 382
  • ISBN : 9780128217313
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Summary : This book will help readers navigate the complexity of mitochondrial disorders, by addressing the role of mitochondrial dysfunction and the complex pathophysiological mechanisms associated with a growing number of illnesses, not only of neurological interest. Further, it provides updated concepts on genotype-phenotype correlations, clinical syndromes, diagnostic algorithms and therapies. Written ...

Mitochondrial Dynamics and Neurodegeneration

Mitochondrial Dynamics and Neurodegeneration
  • Author : Bingwei Lu
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-05-16
  • Total pages : 260
  • ISBN : 9780128217313
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Summary : Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this ...

The Functions Disease Related Dysfunctions and Therapeutic Targeting of Neuronal Mitochondria

The Functions  Disease Related Dysfunctions  and Therapeutic Targeting of Neuronal Mitochondria
  • Author : J. Marie Hardwick
  • Publisher : John Wiley & Sons
  • Release Date : 2015-09-21
  • Total pages : 448
  • ISBN : 9780128217313
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Summary : This book presents advances in the field of neuronal mitochondria – functions, relation to therapeutics, and pharmacology. For scientists and researchers in both industry and academia, this book provides detailed discussion, examples, and approaches, to illustrate the potential of mitochondria as therapeutic targets for neuronal diseases. • Helps readers understand the regulation ...

Mitochondrial Disorders in Neurology

Mitochondrial Disorders in Neurology
  • Author : Anthony H.V. Schapira,S. Dimauro
  • Publisher : Butterworth-Heinemann
  • Release Date : 2013-10-22
  • Total pages : 264
  • ISBN : 9780128217313
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Summary : Mitochondrial Disorders in Neurology provides an overview of mitochondrial diseases. This book discusses the effects of mitochondrial dysfunction based on the relevant biochemistry and molecular genetics. The abnormal muscle and mitochondrial morphology in a variety of clinical presentations from isolated ophthalmoplegia to severe encephalopathy are also elaborated. This text likewise ...

Intractable Neurological Disorders Human Genome Research and Society

Intractable Neurological Disorders  Human Genome Research and Society
  • Author : Norio Fujiki,Darryl Raymund Johnson Macer
  • Publisher : Unknown
  • Release Date : 1994
  • Total pages : 316
  • ISBN : 9780128217313
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Summary : Download or read online Intractable Neurological Disorders Human Genome Research and Society written by Norio Fujiki,Darryl Raymund Johnson Macer, published by which was released on 1994. Get Intractable Neurological Disorders Human Genome Research and Society Books now! Available in PDF, ePub and Kindle....

Molecular Analysis of Mitochondrial DNA in Neurological Disorders

Molecular Analysis of Mitochondrial DNA in Neurological Disorders
  • Author : Denise Stephania Rath
  • Publisher : Unknown
  • Release Date : 1992
  • Total pages : 170
  • ISBN : 9780128217313
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Summary : Download or read online Molecular Analysis of Mitochondrial DNA in Neurological Disorders written by Denise Stephania Rath, published by which was released on 1992. Get Molecular Analysis of Mitochondrial DNA in Neurological Disorders Books now! Available in PDF, ePub and Kindle....

Mitochondrial Dynamics and Neurodegeneration

Mitochondrial Dynamics and Neurodegeneration
  • Author : Bingwei Lu
  • Publisher : Springer
  • Release Date : 2013-01-02
  • Total pages : 260
  • ISBN : 9780128217313
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Summary : Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this ...

Mitochondrial Case Studies

Mitochondrial Case Studies
  • Author : Russell Saneto,Sumit Parikh,Bruce H Cohen
  • Publisher : Academic Press
  • Release Date : 2015-11-24
  • Total pages : 338
  • ISBN : 9780128217313
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Summary : Mitochondrial Case Studies: Underlying Mechanisms and Diagnosis offers the science behind mitochondrial disease with a case studies approach. Since mitochondrial diseases are diverse and influenced by genetic, environmental, and social-economic factors, this publication will help students, physicians, scientists, health care students, and families recognize and accurately diagnose mitochondrial disease and ...

Molecular Basis of Neurological Disorders and Their Treatment

Molecular Basis of Neurological Disorders and Their Treatment
  • Author : J.W. Gorrod,A. Albano,E. Ferrari,S. Papa
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Total pages : 337
  • ISBN : 9780128217313
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Summary : cytochemical techniques (ICC) which provide a useful adjunct to investigations by immunoblotting. A particular advantage of a cytochemical approach to the investiga tion of mitochondrial disorders is that it allows the mosaic distribution of certain of these defects to be detected, whereas the tissue homogeniza tion involved in conventional enzyme ...

Mitochondria dependent Local Caspase Activation and Mitofusin 2 mediated Mitophagy in Neurodegeneration

Mitochondria dependent Local Caspase Activation and Mitofusin 2 mediated Mitophagy in Neurodegeneration
  • Author : Hao Chen
  • Publisher : Unknown
  • Release Date : 2020
  • Total pages : 212
  • ISBN : 9780128217313
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Summary : Mitochondria are critical regulators of neuronal physiology. They play a pivotal role in energy supply and Ca2+ buffering. Thus, mitochondria can sustain the synapse and neuronal function. In this regard, the mitochondria with an impaired capacity of bioenergetics or Ca2+ buffering will lead to synapse failure and neurodegeneration. Moreover, emerging ...

Mutations of Mitochondrial DNA Polymerase Gamma

Mutations of Mitochondrial DNA Polymerase Gamma
  • Author : Petri T. Luoma
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 80
  • ISBN : 9780128217313
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Summary : Download or read online Mutations of Mitochondrial DNA Polymerase Gamma written by Petri T. Luoma, published by which was released on 2007. Get Mutations of Mitochondrial DNA Polymerase Gamma Books now! Available in PDF, ePub and Kindle....