Microfluidic Cell Culture Systems

Written By Jeffrey T Borenstein
Microfluidic Cell Culture Systems
  • Publsiher : Elsevier
  • Release : 12 September 2018
  • ISBN : 0128136723
  • Pages : 396 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Microfluidic Cell Culture Systems written by Jeffrey T Borenstein which was release on 12 September 2018, this book published by Elsevier. Available in PDF, EPUB and Kindle Format. Book excerpt: Techniques for microfabricating intricate microfluidic structures that mimic the microenvironment of tissues and organs, combined with the development of biomaterials with carefully engineered surface properties, have enabled new paradigms in and cell culture-based models for human diseases. The dimensions of surface features and fluidic channels made accessible by these techniques are well-suited to the size scale of biological cells. Microfluidic Cell Culture Systems applies design and experimental techniques used in in microfluidics, and cell culture technologies to organ-on-chip systems. This book is intended to serve as a professional reference, providing a practical guide to design and fabrication of microfluidic systems and biomaterials for use in cell culture systems and human organ models. The book covers topics ranging from academic first principles of microfluidic design, to clinical translation strategies for cell culture protocols. The goal is to help professionals coming from an engineering background to adapt their expertise for use in cell culture and organ models applications, and likewise to help biologists to design and employ microfluidic technologies in their cell culture systems. This 2nd edition contains new material that strengthens the focus on in vitro models useful for drug discovery and development. One new chapter reviews liver organ models from an industry perspective, while others cover new technologies for scaling these models and for multi-organ systems. Other new chapters highlight the development of organ models and systems for specific applications in disease modeling and drug safety. Previous chapters have been revised to reflect the latest advances. Provides design and operation methodology for microfluidic and microfabricated materials and devices for organ-on-chip disease and safety models. This is a rapidly expanding field that will continue to grow along with advances in cell biology and microfluidics technologies. Comprehensively covers strategies and techniques ranging from academic first principles to industrial scale-up approaches. Readers will gain insight into cell-material interactions, microfluidic flow, and design principles. Offers three fundamental types of information: 1) design principles, 2) operation techniques, and 3) background information/perspectives. The book is carefully designed to strike a balance between these three areas, so it will be of use to a broad range of readers with different technical interests and educational levels.

Microfluidic Cell Culture Systems

Microfluidic Cell Culture Systems
  • Author : Jeffrey T Borenstein,Vishal Tandon,Sarah L Tao,Joseph L. Charest
  • Publisher : Elsevier
  • Release Date : 2018-09-12
  • Total pages : 396
  • ISBN : 0128136723
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Summary : Techniques for microfabricating intricate microfluidic structures that mimic the microenvironment of tissues and organs, combined with the development of biomaterials with carefully engineered surface properties, have enabled new paradigms in and cell culture-based models for human diseases. The dimensions of surface features and fluidic channels made accessible by these techniques ...

Microfluidic Cell Culture Systems

Microfluidic Cell Culture Systems
  • Author : Jeffrey T. Borenstein,Vishal Tandon,Joseph L. Charest,Sarah L. Tao
  • Publisher : Micro and Nano Technologies
  • Release Date : 2018-06
  • Total pages : 500
  • ISBN : 0128136723
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Summary : Microfluidic Cell Culture Systems, Second Edition, applies the design and experimental techniques used in MEMS microfabrication and microfluidics to cell culture systems. The book serves as a professional reference, providing a practical guide to the design and fabrication of microfluidic systems and biomaterials for use in cell culture systems and ...

Engineering Microfluidic Cell Culture Systems for Studying Spatiotemporal Effects in Immune Responses

Engineering Microfluidic Cell Culture Systems for Studying Spatiotemporal Effects in Immune Responses
  • Author : Tino Frank
  • Publisher : Unknown
  • Release Date : 2016
  • Total pages : 212
  • ISBN : 0128136723
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Summary : Download or read online Engineering Microfluidic Cell Culture Systems for Studying Spatiotemporal Effects in Immune Responses written by Tino Frank, published by which was released on 2016. Get Engineering Microfluidic Cell Culture Systems for Studying Spatiotemporal Effects in Immune Responses Books now! Available in PDF, ePub and Kindle....

Development of Microfluidic Cell Culture Platforms for Investigating Cellular Phenomena

Development of Microfluidic Cell Culture Platforms for Investigating Cellular Phenomena
  • Author : Bryson McKinley Brewer
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 212
  • ISBN : 0128136723
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Summary : Download or read online Development of Microfluidic Cell Culture Platforms for Investigating Cellular Phenomena written by Bryson McKinley Brewer, published by which was released on 2015. Get Development of Microfluidic Cell Culture Platforms for Investigating Cellular Phenomena Books now! Available in PDF, ePub and Kindle....

Multiplexed Microfabricated Cell Culture Device for Stem Cell Process Development

Multiplexed Microfabricated Cell Culture Device for Stem Cell Process Development
  • Author : M. Reichen
  • Publisher : Unknown
  • Release Date : 2012
  • Total pages : 212
  • ISBN : 0128136723
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Summary : In this thesis, a multiplexed micro-fabricated cell culture device is presented to probe the soluble micro-environment of stem cells. A large number of biological, physical and chemical variables determine the micro-environment of stem cells and affect therefore their fate. The soluble micro-environment is believed to play a pivotal role in ...

Cardiac Cell Culture Technologies

Cardiac Cell Culture Technologies
  • Author : Zbigniew Brzozka,Elzbieta Jastrzebska
  • Publisher : Springer
  • Release Date : 2017-11-21
  • Total pages : 234
  • ISBN : 0128136723
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Summary : This book provides an introduction to the biological background of heart functioning and analyzes the various materials and technologies used for the development of microfluidic systems dedicated to cell culture, with an emphasis on cardiac cells. The authors describe the characterization of microfluidic systems for cardiac cell culture and center ...

Microfluidic Cell Culture Systems

Microfluidic Cell Culture Systems
  • Author : Christopher Bettinger,Jeffrey T Borenstein,Sarah L Tao
  • Publisher : William Andrew
  • Release Date : 2012-12-31
  • Total pages : 452
  • ISBN : 0128136723
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Summary : The fields of microfluidics and BioMEMS are significantly impacting cell biology research and applications through the application of engineering solutions to human disease and health problems. The dimensions of microfluidic channels are well suited to the physical scale of biological cells, and the many advantages of microfluidics make it an ...

Microfluidic Systems for Neuronal Cell Culture

Microfluidic Systems for Neuronal Cell Culture
  • Author : Alex Johnstone
  • Publisher : Unknown
  • Release Date : 2016
  • Total pages : 212
  • ISBN : 0128136723
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Summary : Download or read online Microfluidic Systems for Neuronal Cell Culture written by Alex Johnstone, published by which was released on 2016. Get Microfluidic Systems for Neuronal Cell Culture Books now! Available in PDF, ePub and Kindle....

Cardiac Cell Culture Technologies

Cardiac Cell Culture Technologies
  • Author : Zbigniew Brzozka,Elzbieta Jastrzebska
  • Publisher : Springer
  • Release Date : 2018-09-04
  • Total pages : 234
  • ISBN : 0128136723
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Summary : This book provides an introduction to the biological background of heart functioning and analyzes the various materials and technologies used for the development of microfluidic systems dedicated to cell culture, with an emphasis on cardiac cells. The authors describe the characterization of microfluidic systems for cardiac cell culture and center ...

Medical and Industrial Applications of Microfluidic based Cell Tissue Culture and Organs on a Chip Advances in Organs on a Chip and Organoids Technologies

Medical and Industrial Applications of Microfluidic based Cell Tissue Culture and Organs on a Chip  Advances in Organs on a Chip and Organoids Technologies
  • Author : Qasem Ramadan,Massimo Alberti,Martin Dufva,Yi-Chung Tung
  • Publisher : Frontiers Media SA
  • Release Date : 2019-10-16
  • Total pages : 212
  • ISBN : 0128136723
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Summary : Recent developments in microfluidics have demonstrated enormous potential of microscale cell culture for biology studies and recognized as instrumental in performing rapid and efficient experiments on small-sample volumes. Microfluidic-based cell culture is an area of research that keeps growing and gaining importance as a prominent technology, able to link scientific ...

Microfluidic Systems for Automatic Cell Culture and Precise Sampling

Microfluidic Systems for Automatic Cell Culture and Precise Sampling
  • Author : 黃俊維
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 140
  • ISBN : 0128136723
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Summary : Download or read online Microfluidic Systems for Automatic Cell Culture and Precise Sampling written by 黃俊維, published by which was released on 2007. Get Microfluidic Systems for Automatic Cell Culture and Precise Sampling Books now! Available in PDF, ePub and Kindle....

Studying Intercellular Signaling Underlying Human Diseases Using Open Microfluidic Coculture

Studying Intercellular Signaling Underlying Human Diseases Using Open Microfluidic Coculture
  • Author : Tianzi Zhang
  • Publisher : Unknown
  • Release Date : 2020
  • Total pages : 153
  • ISBN : 0128136723
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Summary : This dissertation focuses on the development of innovative open microfluidic cell culture platforms and their application in studying intercellular signaling underlying human diseases in controlled ex vivo microenvironments. Chapter 1 introduces the background of open microfluidic capillary systems, including the design considerations and current fabrication techniques, and addresses the advantages of ...

Organs on chips for the pharmaceutical development process

Organs on chips for the pharmaceutical development process
  • Author : Jonas Christoffersson
  • Publisher : Linköping University Electronic Press
  • Release Date : 2019-01-22
  • Total pages : 78
  • ISBN : 0128136723
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Summary : Organs-on-chips are dynamic cell culture devices created with the intention to mimic organ function in vitro. Their purpose is to assess the toxicity and efficacy of drugs and, as early as possible in the pharmaceutical development process, predict the outcome of clinical trials. The aim of this thesis is to ...

Development of Microfluidic Systems for Micro scale Animal Cell Culture from Cell Separation Microencapsulation Micro dispensing to Perfusion 3 dimensional Cell Culture

Development of Microfluidic Systems for Micro scale Animal Cell Culture  from Cell Separation  Microencapsulation  Micro dispensing to Perfusion 3 dimensional Cell Culture
  • Author : 黃菘斌
  • Publisher : Unknown
  • Release Date : 2010
  • Total pages : 264
  • ISBN : 0128136723
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Summary : Download or read online Development of Microfluidic Systems for Micro scale Animal Cell Culture from Cell Separation Microencapsulation Micro dispensing to Perfusion 3 dimensional Cell Culture written by 黃菘斌, published by which was released on 2010. Get Development of Microfluidic Systems for Micro scale Animal Cell Culture from Cell Separation Microencapsulation Micro dispensing ...

Cell Analysis on Microfluidics

Cell Analysis on Microfluidics
  • Author : Jin-Ming Lin
  • Publisher : Springer
  • Release Date : 2017-10-25
  • Total pages : 429
  • ISBN : 0128136723
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Summary : This book presents a detailed overview of the design, formatting, application, and development of microfluidic chips in the context of cell biology research, enumerating each element involved in microfluidics-based cell analysis, discussing its history, status quo, and future prospects, It also offers an extensive review of the research completed in ...