Late Stage Fluorination of Bioactive Molecules and Biologically Relevant Substrates

Written By Al Postigo
Late Stage Fluorination of Bioactive Molecules and Biologically Relevant Substrates
  • Publsiher : Elsevier
  • Release : 05 September 2018
  • ISBN : 0128130393
  • Pages : 390 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Late Stage Fluorination of Bioactive Molecules and Biologically Relevant Substrates written by Al Postigo which was release on 05 September 2018, this book published by Elsevier. Available in PDF, EPUB and Kindle Format. Book excerpt: Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the authors' expert knowledge, this book provides researchers with a broad set of applicable methods to use in their work. Highlights the latest developments in the field in a concise volume Provides details of key fluorinating reagents across diverse families of organic compounds Explores the current applications and future potential of fluorine in drug development

Late Stage Fluorination of Bioactive Molecules and Biologically Relevant Substrates

Late Stage Fluorination of Bioactive Molecules and Biologically Relevant Substrates
  • Author : Al Postigo
  • Publisher : Elsevier
  • Release Date : 2018-09-05
  • Total pages : 390
  • ISBN : 0128130393
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Summary : Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of ...

Nontraditional Activation Methods in Green and Sustainable Applications

Nontraditional Activation Methods in Green and Sustainable Applications
  • Author : Bela Torok,Christian Schaefer
  • Publisher : Elsevier
  • Release Date : 2021-02-28
  • Total pages : 604
  • ISBN : 0128130393
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Summary : Nontraditional Activation Methods in Green and Sustainable Applications: Microwaves; Ultrasounds; Photo-, Electro- and Mechan-ochemistry and High Hydrostatic Pressure provides a broad overview of non-traditional activation methods to help readers identify and use appropriate approaches in reducing the environmental impact of their work. Sections discuss the fundamental principles of each method ...