Ion Channels and Transporters of Epithelia in Health and Disease

Written By Kirk L. Hamilton
Ion Channels and Transporters of Epithelia in Health and Disease
  • Publsiher : Springer
  • Release : 14 December 2015
  • ISBN : 1493933663
  • Pages : 1019 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Ion Channels and Transporters of Epithelia in Health and Disease written by Kirk L. Hamilton which was release on 14 December 2015, this book published by Springer. Available in PDF, EPUB and Kindle Format. Book excerpt: This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the basic cellular models and functions by means of a compelling clinical perspective, addressing aspects from the laboratory bench to the bedside. The individual chapters, written by leading scientists and clinicians, explore specific ion channels and transporters located in the epithelial tissues of the kidney, intestine, pancreas and respiratory tract, all of which play a crucial part in maintaining homeostasis. Further topics include the fundamentals of epithelial transport; mathematical modeling of ion transport; cell volume regulation; membrane protein folding and trafficking; transepithelial transport functions; and lastly, a discussion of transport proteins as potential pharmacological targets with a focus on the pharmacology of potassium channels.

Ion Channels and Transporters of Epithelia in Health and Disease

Ion Channels and Transporters of Epithelia in Health and Disease
  • Author : Kirk L. Hamilton,Daniel C Devor
  • Publisher : Springer
  • Release Date : 2015-12-14
  • Total pages : 1019
  • ISBN : 1493933663
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Summary : This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the basic cellular models and functions by means of a compelling clinical perspective, addressing aspects from the laboratory bench to the bedside. The individual chapters, written by leading scientists and ...

Ion Channels in Health and Disease

Ion Channels in Health and Disease
  • Author : Geoffrey S. Pitt
  • Publisher : Academic Press
  • Release Date : 2016-10-04
  • Total pages : 392
  • ISBN : 1493933663
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Summary : Ion Channels in Health and Disease provides key insight to allow researchers to generate discoveries across disease states. A single resource that integrates disparate areas of biology and disease ion channel biology, this publication includes cross-referencing for disease, channels, and tissues. Offers a broad view of research of interest to ...

Ion Channels in Health and Sickness

Ion Channels in Health and Sickness
  • Author : Fatima Shad Kaneez
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-10-10
  • Total pages : 202
  • ISBN : 1493933663
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Summary : Ion channels are proteins that make pores in the membranes of excitable cells present both in the brain and the body. These cells are not only responsible for converting chemical and mechanical stimuli into the electrical signals but are also liable for monitoring vital functions. All our activities, from the ...

Ion Transport Across Epithelial Tissues and Disease

Ion Transport Across Epithelial Tissues and Disease
  • Author : Kirk L. Hamilton,Daniel C. Devor
  • Publisher : Springer
  • Release Date : 2021-01-23
  • Total pages : 382
  • ISBN : 1493933663
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Summary : This book discusses the unique ion channels and transporters found within the epithelial tissues of various organs, including the kidney, intestine, pancreas and respiratory tract. Authors focus on demonstrating the crucial roles that each of these channels and transporters play in transepithelial ion and fluid transport across epithelia, as well ...

Ion Channels and Disease

Ion Channels and Disease
  • Author : Frances M. Ashcroft
  • Publisher : Academic Press
  • Release Date : 1999-10-20
  • Total pages : 481
  • ISBN : 1493933663
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Summary : Ion channels are membrane proteins that act as gated pathways for the movement of ions across cell membranes. They play essential roles in the physiology of all cells. In recent years, an ever-increasing number of human and animal diseases have been found to result from defects in ion channel function. ...

Studies of Epithelial Transporters and Ion Channels

Studies of Epithelial Transporters and Ion Channels
  • Author : Kirk L. Hamilton,Daniel C. Devor
  • Publisher : Springer Nature
  • Release Date : 2020
  • Total pages : 1244
  • ISBN : 1493933663
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Summary : "This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. The authors will show, that each of these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their responsibility ...

Potassium Channels in Health and Disease

Potassium Channels in Health and Disease
  • Author : Hiroaki Kume, Ph.d.
  • Publisher : Unknown
  • Release Date : 2017-12
  • Total pages : 136
  • ISBN : 1493933663
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Summary : Potassium ion (K+) channels are ubiquitous components and are widely distributed on the surface of the cell membrane in various tissues. There are many types of potassium ion channels (voltage-gated K+ channels, ATP-sensitive K+ channels, Ca2+-activated K+ channels, etc.), and each type of potassium ion channel has its own ...

Ion Channels Down Under

Ion Channels Down Under
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2017-05-18
  • Total pages : 336
  • ISBN : 1493933663
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Summary : Ion Channels Down Under, Volume 79 provides up-to-date information on ion channel pharmacology, their pharmacological modulators, and role in a diverse range of poorly treated medical conditions. Contributors include prominent scientists and highly-recognized experts with major accomplishments in the field of ion channel pharmacology. Topics covered include the role of ion ...

TRP Channels in Health and Disease

TRP Channels in Health and Disease
  • Author : Alexander Dietrich
  • Publisher : MDPI
  • Release Date : 2019-06-25
  • Total pages : 266
  • ISBN : 1493933663
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Summary : Almost 25 years ago, the first mammalian transient receptor potential (TRP) channel was cloned and published. TRP channels now represent an extended family of 28 members fulfilling multiple roles in the living organism. Identified functions include control of body temperature, transmitter release, mineral homeostasis, chemical sensing, and survival mechanisms in a challenging ...

TRP Channels in Health and Disease

TRP Channels in Health and Disease
  • Author : Arpad Szallasi
  • Publisher : Nova Biomedical
  • Release Date : 2011
  • Total pages : 563
  • ISBN : 1493933663
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Summary : Changes in temperature, either hot or cold, is sensed through direct activation of members of the temperature-sensitive transient release potential (TRP) ion channel superfamily, the so-called "thermoTRPs". Of the 28 TRP channels discovered today, seven sense hot or warm temperatures whereas two are activated by cold. Together, these channels cover a ...

Basic Epithelial Ion Transport Principles and Function

Basic Epithelial Ion Transport Principles and Function
  • Author : Kirk L. Hamilton,Daniel C. Devor
  • Publisher : Springer Nature
  • Release Date : 2020-11-26
  • Total pages : 563
  • ISBN : 1493933663
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Summary : This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. As the authors show, these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their contribution to maintaining homeostasis. ...

Developing a ubiquitous Toolkit for Modulating Ion Channel Expression in Health Disease

Developing a  ubiquitous  Toolkit for Modulating Ion Channel Expression in Health   Disease
  • Author : Scott Arthur Kanner
  • Publisher : Unknown
  • Release Date : 2021
  • Total pages : 212
  • ISBN : 1493933663
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Summary : To address this barrier, I developed a novel nanobody-based toolset to selectively - and bidirectionally - manipulate the ubiquitin status and functional expression of target ion channels for basic study and therapeutic rescue....

BK Channels Integrators of Cellular Signals in Health and Disease

BK Channels  Integrators of Cellular Signals in Health and Disease
  • Author : Thomas M. Weiger,Alex Dopico,Anton Hermann
  • Publisher : Frontiers Media SA
  • Release Date : 2017-11-10
  • Total pages : 212
  • ISBN : 1493933663
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Summary : Maxi calcium-activated potassium channels (BK) are an amazing category of ion channels which are found in cellular plasma membranes as well as in membranes of intracellular organelles. The function of these channels is to repolarize any excited membrane by passing a potassium outward current, in response to depolarization and/or ...

Handbook of Ion Channels

Handbook of Ion Channels
  • Author : Ji'e Zheng,Matthew C. Trudeau
  • Publisher : CRC Press
  • Release Date : 2016-10
  • Total pages : 691
  • ISBN : 1493933663
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Summary : The New Benchmark for Understanding the Latest Developments of Ion Channels Ion channels control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli, and regulate the response to physical stimuli. They can often interact with the cellular environment due to their location at ...

Ion Channels in the Pulmonary Vasculature

Ion Channels in the Pulmonary Vasculature
  • Author : Jason X.-J. Yuan
  • Publisher : CRC Press
  • Release Date : 2005-05-12
  • Total pages : 832
  • ISBN : 1493933663
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Summary : This volume presents a global overview of the role of ion flux via transmembrane ion channel proteins in the regulation of pulmonary vascular tone and in the vascular remodeling processes associated with pulmonary vascular disease-offering a comprehensive review of the multiple families of ion channels that have been identified and ...