Formulation tools for Pharmaceutical Development

Written By J E Aguilar
Formulation tools for Pharmaceutical Development
  • Publsiher : Elsevier
  • Release : 30 September 2013
  • ISBN : 1908818506
  • Pages : 304 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Formulation tools for Pharmaceutical Development written by J E Aguilar which was release on 30 September 2013, this book published by Elsevier. Available in PDF, EPUB and Kindle Format. Book excerpt: A range of new and innovative tools used for preformulation and formulation of medicines help optimize pharmaceutical development projects. Such tools also assist with the performance evaluation of the pharmaceutical process, allowing any potential gaps to be identified. These tools can be applied in both basic research and industrial environment. Formulation tools for pharmaceutical development considers these key research and industrial tools. Nine chapters by leading contributors cover: Artificial neural networks technology to model, understand, and optimize drug formulations; ME_expert 2.0: a heuristic decision support system for microemulsions formulation development; Expert system for the development and formulation of push-pull osmotic pump tablets containing poorly water-soluble drugs; SeDeM Diagram: an expert system for preformulation, characterization and optimization of tables obtained by direct compression; New SeDeM-ODT expert system: an expert system for formulation of orodispersible tablets obtained by direct compression; and 3D-cellular automata in computer-aided design of pharmaceutical formulations: mathematical concept and F-CAD software. Coverage of artificial intelligence tools, new expert systems, understanding of pharmaceutical processes, robust development of medicines, and new ways to develop medicines Development of drugs and medicines using mathematical tools Compilation of expert system developed around the world

Formulation tools for Pharmaceutical Development

Formulation tools for Pharmaceutical Development
  • Author : J E Aguilar
  • Publisher : Elsevier
  • Release Date : 2013-09-30
  • Total pages : 304
  • ISBN : 1908818506
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Summary : A range of new and innovative tools used for preformulation and formulation of medicines help optimize pharmaceutical development projects. Such tools also assist with the performance evaluation of the pharmaceutical process, allowing any potential gaps to be identified. These tools can be applied in both basic research and industrial environment. ...

Handbook of Pharmaceutical Granulation Technology

Handbook of Pharmaceutical Granulation Technology
  • Author : Dilip M. Parikh
  • Publisher : CRC Press
  • Release Date : 2021-05-19
  • Total pages : 816
  • ISBN : 1908818506
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Summary : This fully revised edition of Handbook of Pharmaceutical Granulation Technology covers the rapid advances in the science of agglomeration, process control, process modelling, scale-up, emerging particle engineering technologies, along with current regulatory changes presented by some of the prominent scientist and subject matter experts around the globe. Learn from more ...

Computer aided applications in pharmaceutical technology

Computer aided applications in pharmaceutical technology
  • Author : Ljiljana Djekic,Dragana Vasiljevic,Marija Primorac
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-04-10
  • Total pages : 300
  • ISBN : 1908818506
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Summary : This chapter introduces the concept of formulation development assisted by computer applications. Development and optimization of various types of pharmaceutical emulsions microemulsions, self-microemulsifying systems, and double emulsions are presented. Illustrative examples are presented to demonstrate the ability of computer-aided tools to facilitate formulation development. Various techniques, such as design of ...

Water Insoluble Drug Formulation

Water Insoluble Drug Formulation
  • Author : Ron Liu
  • Publisher : CRC Press
  • Release Date : 2018-03-12
  • Total pages : 736
  • ISBN : 1908818506
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Summary : Properties and Formulation: From Theory to Real-World Application Scientists have attributed more than 40 percent of the failures in new drug development to poor biopharmaceutical properties, particularly water insolubility. Issues surrounding water insolubility can postpone or completely derail important new drug development. Even the much-needed reformulation of currently marketed products can ...

3D Printing of Pharmaceuticals and Drug Delivery Devices

3D Printing of Pharmaceuticals and Drug Delivery Devices
  • Author : Dimitrios A. Lamprou
  • Publisher : MDPI
  • Release Date : 2020-07-01
  • Total pages : 436
  • ISBN : 1908818506
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Summary : The 3D printing (3DP) process was patented in 1986; however, only in the last decade has it begun to be used for medical applications, as well as in the fields of prosthetics, bio-fabrication, and pharmaceutical printing. 3DP or additive manufacturing (AM) is a family of technologies that implement layer-by-layer processes in ...

Multivariate Analysis in the Pharmaceutical Industry

Multivariate Analysis in the Pharmaceutical Industry
  • Author : Ana Patricia Ferreira,Jose C. Menezes,Mike Tobyn
  • Publisher : Academic Press
  • Release Date : 2018-04-24
  • Total pages : 464
  • ISBN : 1908818506
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Summary : Multivariate Analysis in the Pharmaceutical Industry provides industry practitioners with guidance on multivariate data methods and their applications over the lifecycle of a pharmaceutical product, from process development, to routine manufacturing, focusing on the challenges specific to each step. It includes an overview of regulatory guidance specific to the use ...

Developing Solid Oral Dosage Forms

Developing Solid Oral Dosage Forms
  • Author : Yihong Qiu,Yisheng Chen,Geoff G.Z. Zhang,Lawrence Yu,Rao V. Mantri
  • Publisher : Academic Press
  • Release Date : 2016-11-08
  • Total pages : 1176
  • ISBN : 1908818506
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Summary : Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Second Edition illustrates how to develop high-quality, safe, and effective pharmaceutical products by discussing the latest techniques, tools, and scientific advances in preformulation investigation, formulation, process design, characterization, scale-up, and production operations. This book covers the essential principles of physical pharmacy, ...

Pharmaceutical Product Development

Pharmaceutical Product Development
  • Author : Vandana B. Patravale,John I. Disouza,Maharukh Rustomjee
  • Publisher : CRC Press
  • Release Date : 2016-05-25
  • Total pages : 433
  • ISBN : 1908818506
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Summary : Pharmaceutical product development is a multidisciplinary activity involving extensive efforts in systematic product development and optimization in compliance with regulatory authorities to ensure the quality, efficacy and safety of resulting products. Pharmaceutical Product Development equips the pharmaceutical formulation scientist with extensive and up-to-date knowledge of drug product development and covers ...

Challenges in Protein Product Development

Challenges in Protein Product Development
  • Author : Nicholas W. Warne,Hanns-Christian Mahler
  • Publisher : Springer
  • Release Date : 2018-07-22
  • Total pages : 599
  • ISBN : 1908818506
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Summary : In this volume, the authors discuss the many significant challenges currently faced in biotechnology dosage form development, providing guidance, shared experience and thoughtful reflection on how best to address these potential concerns. As the field of therapeutic recombinant therapeutic proteins enters its fourth decade and the market for biopharmaceuticals becomes ...

Predictive in Vitro Dissolution Tools

Predictive in Vitro Dissolution Tools
  • Author : Emmanuel Scheubel
  • Publisher : Unknown
  • Release Date : 2010
  • Total pages : 201
  • ISBN : 1908818506
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Summary : Dissolution has emerged as a key method during development of medicines and for quality control of marketed products. At the early stage of development, dissolution guides the selection of toxicology and first test in man formulations. At later stages of development, dissolution tests are performed to compare prototype formulations, the ...

Therapeutic Protein and Peptide Formulation and Delivery

Therapeutic Protein and Peptide Formulation and Delivery
  • Author : Zahra Shahrokh,American Chemical Society. Division of Biochemical Technology
  • Publisher : Amer Chemical Society
  • Release Date : 1997
  • Total pages : 228
  • ISBN : 1908818506
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Summary : This volume reviews protein stability and the analytical and biophysical characterization of proteins. It emphasizes drug delivery approaches, especially local delivery through the skin. Including both academic and industrial perspectives from such companies as Genentech, Amgen, and Merck, the book also discusses novel drug delivery polymers and the development of ...

Predictive Modeling of Pharmaceutical Unit Operations

Predictive Modeling of Pharmaceutical Unit Operations
  • Author : Preetanshu Pandey,Rahul Bharadwaj
  • Publisher : Woodhead Publishing
  • Release Date : 2016-09-26
  • Total pages : 464
  • ISBN : 1908818506
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Summary : The use of modeling and simulation tools is rapidly gaining prominence in the pharmaceutical industry covering a wide range of applications. This book focuses on modeling and simulation tools as they pertain to drug product manufacturing processes, although similar principles and tools may apply to many other areas. Modeling tools ...

Analytical Techniques in the Pharmaceutical Sciences

Analytical Techniques in the Pharmaceutical Sciences
  • Author : Anette Müllertz,Yvonne Perrie,Thomas Rades
  • Publisher : Springer
  • Release Date : 2016-08-30
  • Total pages : 838
  • ISBN : 1908818506
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Summary : The aim of this book is to present a range of analytical methods that can be used in formulation design and development and focus on how these systems can be applied to understand formulation components and the dosage form these build. To effectively design and exploit drug delivery systems, the ...

Monoclonal Antibodies

Monoclonal Antibodies
  • Author : Steven Shire
  • Publisher : Woodhead Publishing
  • Release Date : 2015-04-24
  • Total pages : 224
  • ISBN : 1908818506
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Summary : Monoclonal antibodies (MAbs) are currently the major class of protein bio therapeutic being developed by biotechnology and pharmaceutical companies. Monoclonal Antibodies discusses the challenges and issues revolving around development of a monoclonal antibody produced by recombinant DNA technology into a therapeutic agent.This book covers downstream processing which includes design ...

Polymorphism in the Pharmaceutical Industry

Polymorphism in the Pharmaceutical Industry
  • Author : Rolf Hilfiker,Markus von Raumer
  • Publisher : John Wiley & Sons
  • Release Date : 2019-04-29
  • Total pages : 512
  • ISBN : 1908818506
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Summary : "Polymorphism in the Pharmaceutical Industry - Solid Form and Drug Development" highlights the relevance of polymorphism in modern pharmaceutical chemistry, with a focus on quality by design (QbD) concepts. It covers all important issues by way of case studies, ranging from properties and crystallization, via thermodynamics, analytics and theoretical modelling ...