Formulation of Monoclonal Antibody Therapies

Written By Amal Ali Elkordy
Formulation of Monoclonal Antibody Therapies
  • Publsiher : Academic Press
  • Release : 01 October 2021
  • ISBN : 0128234288
  • Pages : 245 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Formulation of Monoclonal Antibody Therapies written by Amal Ali Elkordy which was release on 01 October 2021, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Formulation of Monoclonal Antibody Therapies: From Lab to Market covers a wide range of topics about therapeutic monoclonal antibodies (mAbs) with a focus on formulation aspects. Therapeutic monoclonal antibodies are used for treatment of chronic diseases. It brings together a comprehensive knowledge in one accessible volume. Starting with foundational information on monoclonal antibodies, the book then discusses the importance of biopharmaceutical products, monoclonal antibodies and biosimilars in treatment of chronic diseases, pharmaceutical aspects of mAbs, and how it can be administered. The industrial point of view and the clinical application of mAbs including in oncology, general medicine, rheumatology, hematology, dermatology, gastrointestinal tract, metabolic diseases and dentistry. Formulation of Monoclonal Antibody Therapies: From Lab to Market is essential reading for researchers in biotechnology and biopharmaceutical fields, academics and pharmaceutical industrial scientists, and university students in pharmaceutical and biopharmaceutical sciences. Covers details of recent advances in using mAbs Examines how to overcome the challenges for formulations of therapeutic mAbs Includes liposomal forms of mAbs

Formulation of Monoclonal Antibody Therapies

Formulation of Monoclonal Antibody Therapies
  • Author : Amal Ali Elkordy
  • Publisher : Academic Press
  • Release Date : 2021-10-01
  • Total pages : 245
  • ISBN : 0128234288
GET BOOK

Summary : Formulation of Monoclonal Antibody Therapies: From Lab to Market covers a wide range of topics about therapeutic monoclonal antibodies (mAbs) with a focus on formulation aspects. Therapeutic monoclonal antibodies are used for treatment of chronic diseases. It brings together a comprehensive knowledge in one accessible volume. Starting with foundational information ...

Pharmaceutical Formulation Development of Peptides and Proteins Second Edition

Pharmaceutical Formulation Development of Peptides and Proteins  Second Edition
  • Author : Lars Hovgaard,Sven Frokjaer,Marco van de Weert
  • Publisher : CRC Press
  • Release Date : 2012-11-14
  • Total pages : 392
  • ISBN : 0128234288
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Summary : The rapid advances in recombinant DNA technology and the increasing availability of peptides and proteins with therapeutic potential are a challenge for pharmaceutical scientists who have to formulate these compounds as drug products. Pharmaceutical Formulation Development of Peptides and Proteins, Second Edition discusses the development of therapeutic peptides and proteins, ...

Monoclonal Antibodies

Monoclonal Antibodies
  • Author : Lei Zheng
  • Publisher : Unknown
  • Release Date : 2014
  • Total pages : 171
  • ISBN : 0128234288
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Summary : This ebook provides a thorough overview of antibody therapy development, including antibody selection, formulation development, conjugation, dose determination, pharmacokinetics/pharmacodynamic, labelling for imaging, and more. Case studies of approved antibodies are included, along with a look ahead to the future by reviewing treatments in clinical development....

Current Trends in Monoclonal Antibody Development and Manufacturing

Current Trends in Monoclonal Antibody Development and Manufacturing
  • Author : Steven J. Shire,Wayne Gombotz,Karoline Bechtold-Peters,James Andya
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-11-11
  • Total pages : 354
  • ISBN : 0128234288
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Summary : Monoclonal antibodies represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Several blockbuster products have been approved over the past several years including Rituxan, Remicade, Avastin, Humira, and Herceptin. In addition, over 300 new drugs are currently in clinical trials. With both large, established biotechnology ...

Novel Approaches and Strategies for Biologics Vaccines and Cancer Therapies

Novel Approaches and Strategies for Biologics  Vaccines and Cancer Therapies
  • Author : Manmohan Singh,Maya Salnikova
  • Publisher : Academic Press
  • Release Date : 2014-12-30
  • Total pages : 520
  • ISBN : 0128234288
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Summary : Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies takes a look at the current strategies, successes and challenges involved with the development of novel formulations of biologics, vaccines and cancer therapy. This thorough reference on the latest trends in the development of diverse modalities will appeal to a ...

Protein Therapeutics 2 Volume Set

Protein Therapeutics  2 Volume Set
  • Author : Tristan Vaughan,Jane Osbourn,Bahija Jallal,Raimund Mannhold,Gerd Folkers,Helmut Buschmann
  • Publisher : John Wiley & Sons
  • Release Date : 2017-12-04
  • Total pages : 768
  • ISBN : 0128234288
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Summary : In this practice-oriented handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and other professionals working in drug development. Following an introduction tracing the rapid development of the protein therapeutics market ...

Ultrafiltration of Highly Concentrated Monoclonal Antibody Solutions

Ultrafiltration of Highly Concentrated Monoclonal Antibody Solutions
  • Author : Elaheh Binabaji
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 212
  • ISBN : 0128234288
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Summary : Monoclonal antibodies are currently the fastest growing segment of the pharmaceutical industry; these products are used in the treatment of a wide range of diseases including cancers and allergies. Antibody products are administered at high doses since the volume that can be delivered by injection is limited. Although ultrafiltration systems ...

High Throughput Formulation Development of Biopharmaceuticals

High Throughput Formulation Development of Biopharmaceuticals
  • Author : Vladimir I. Razinkov,Gerd Kleemann
  • Publisher : Woodhead Publishing
  • Release Date : 2016-09-29
  • Total pages : 132
  • ISBN : 0128234288
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Summary : High Throughput Formulation Development of Biopharmaceuticals: Practical Guide to Methods and Applications provides the latest developments and information on the science of stable and safe drug product formulations, presenting a comprehensive review and detailed description of modern methodologies in the field of formulation development, a process starting with candidate and ...

Therapeutic Monoclonal Antibodies

Therapeutic Monoclonal Antibodies
  • Author : Zhiqiang An
  • Publisher : John Wiley & Sons
  • Release Date : 2011-09-20
  • Total pages : 896
  • ISBN : 0128234288
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Summary : 70-chapter authoritative reference that covers therapeutic monoclonal antibody discovery, development, and clinical applications while incorporating principles, experimental data, and methodologies. First book to address the discovery and development of antibody therapeutics in their entirety. Most chapters contain experimental data to illustrate the principles described in them. Authors provide detailed methodologies ...

Targeted Nanopreparations for Cancer Therapy

Targeted Nanopreparations for Cancer Therapy
  • Author : Radhika Narayanaswamy
  • Publisher : Unknown
  • Release Date : 2020
  • Total pages : 149
  • ISBN : 0128234288
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Summary : "Cancer therapy in the recent years has evolved with the development of novel targeted drug delivery systems. The conventional chemotherapy approach is plagued by side effects and numerous disadvantages such as low bioavailability, poor solubility of drugs, toxicity, non-specific drug action and so forth. With the main goal of producing ...

Development of Antibody Based Therapeutics

Development of Antibody Based Therapeutics
  • Author : Mohammad A. Tabrizi,Gadi G. Bornstein,Scott L. Klakamp
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-04-24
  • Total pages : 426
  • ISBN : 0128234288
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Summary : Translational strategies for development of antibody-based therapeutics should allow understanding of the relationship between the ‘unit dose’ and ‘unit effect’ with respect to both beneficial and deleterious effects from early stages of development. The flow of information from later to earlier stages of development should provide opportunities to facilitate selection ...

Biophysics for Therapeutic Protein Development

Biophysics for Therapeutic Protein Development
  • Author : Linda O. Narhi
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-02-26
  • Total pages : 293
  • ISBN : 0128234288
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Summary : This book can be used to provide insight into this important application of biophysics for those who are planning a career in protein therapeutic development, and for those outside this area who are interested in understanding it better. The initial chapters describe the underlying theory, and strengths and weaknesses of ...

Drug Delivery Systems Third Edition

Drug Delivery Systems  Third Edition
  • Author : Vasant V. Ranade,John B. Cannon
  • Publisher : CRC Press
  • Release Date : 2011-04-25
  • Total pages : 608
  • ISBN : 0128234288
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Summary : Drug delivery technologies represent a vast, vital area of research and development in pharmaceuticals. The demand for innovative drug delivery systems continues to grow, driving a variety of new developments. Drug Delivery Systems, Third Edition provides a comprehensive review of the latest research and development on drug delivery systems. Coverage ...

Therapeutic Peptides and Proteins

Therapeutic Peptides and Proteins
  • Author : Ajay K. Banga
  • Publisher : CRC Press
  • Release Date : 2005-09-14
  • Total pages : 376
  • ISBN : 0128234288
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Summary : Upon publication of the first edition of Therapeutic Peptides and Proteins ten years ago there were only 19 biotechology medicines on the market. Currently there are more than 100, with at least 400 more in various stages of development. That alone would be grounds for a new edition. Add to that the fact ...

Development of Biopharmaceutical Drug Device Products

Development of Biopharmaceutical Drug Device Products
  • Author : Feroz Jameel,John W. Skoug,Robert R. Nesbitt
  • Publisher : Springer Nature
  • Release Date : 2020-03-13
  • Total pages : 893
  • ISBN : 0128234288
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Summary : The biotechnology/biopharmaceutical sector has tremendously grown which led to the invention of engineered antibodies such as Antibody Drug Conjugates (ADCs), Bispecific T-cell engager (BITES), Dual Variable Domain (DVD) antibodies, and fusion proteins that are currently being used as therapeutic agents for immunology, oncology and other disease conditions. Regulatory agencies ...