Fibroblast Growth Factor 23

Written By Christian Faul
Fibroblast Growth Factor 23
  • Publsiher : Elsevier
  • Release : 06 April 2021
  • ISBN : 0128180374
  • Pages : 376 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Fibroblast Growth Factor 23 written by Christian Faul which was release on 06 April 2021, this book published by Elsevier. Available in PDF, EPUB and Kindle Format. Book excerpt: Fibroblast Growth Factor 23 describes how FGF23 was initially identified as a bone-derived factor targeting the kidney. As such, sections in this comprehensive book cover exciting research that shows that different FGF23 effects require distinct signaling receptors and mediators that differ among target tissues, cover FGF23 initially identified as a bone-derived factor targeting the kidney, look at FGF23 as a regulator of phosphate metabolism and beyond, and cover research on novel concepts of FGF receptor signaling. Additional sections cover biochemistry, pharmacology and nephrology, making this book an ideal reference source on FGF23. Provides a comprehensive collection of chapters on the diversity of FGF23's actions Highlights truly translational topics, from molecular signaling to physiology and mechanism of disease, discussing cell culture and animal models to study FGF23 Describes FGF23’s potential in the clinical setting as a biomarker or even drug target Presents leaders in the field who cover a wide spectrum of research backgrounds and expertise, including clinical and basic scientists who specialize in diseases, endocrinology, genetics, protein biochemistry, cell biology and physiology

Fibroblast Growth Factor 23

Fibroblast Growth Factor 23
  • Author : Christian Faul,Kenneth White,Orlando Gutierrez
  • Publisher : Elsevier
  • Release Date : 2021-04-06
  • Total pages : 376
  • ISBN : 0128180374
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Summary : Fibroblast Growth Factor 23 describes how FGF23 was initially identified as a bone-derived factor targeting the kidney. As such, sections in this comprehensive book cover exciting research that shows that different FGF23 effects require distinct signaling receptors and mediators that differ among target tissues, cover FGF23 initially identified as a bone-derived ...

Fibroblast Growth Factor 23 in Canine Kidney Disease

Fibroblast Growth Factor 23 in Canine Kidney Disease
  • Author : Laura M. Harjes
  • Publisher : Unknown
  • Release Date : 2017
  • Total pages : 39
  • ISBN : 0128180374
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Summary : Chronic kidney disease (CKD) is associated with hyperphosphatemia, reduced vitamin D metabolite concentrations, and hyperparathyroidism. This syndrome is known as CKD-mineral and bone disorder (CKD-MBD). Recently it has been shown that increased fibroblast growth factor-23 (FGF23) concentration is one of the earliest biomarkers of CKD in people and cats. It ...

The Role of Circulating Fibroblast Growth Factor 23 FGF 23 in Chronic Kidney Disease Mineral Bone Disorder CKB MBD

The Role of Circulating Fibroblast Growth Factor 23  FGF 23  in Chronic Kidney Disease   Mineral Bone Disorder  CKB MBD
  • Author : Dr. Padmini Ajit Kumar Manghat,King's College London. Guy's, King's and St. Thomas's School of Medicine
  • Publisher : Unknown
  • Release Date : 2012
  • Total pages : 292
  • ISBN : 0128180374
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Summary : Background and aim: Fibroblast Growth Factor-23 (FGF-23) has been shown to be elevated in early stage CKD. The primary stimulus for this increase remains unclear and it is still unknown whether the increase in FGF-23 has a biological effect on bone metabolism and vascular calcification. The aim of the study ...

Fibroblast Growth Factor 23 as Novel Marker of Phosphate Homeostasis

Fibroblast Growth Factor 23 as Novel Marker of Phosphate Homeostasis
  • Author : Noreen Abbas,Aysha Habib Khan
  • Publisher : LAP Lambert Academic Publishing
  • Release Date : 2015-12-10
  • Total pages : 96
  • ISBN : 0128180374
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Summary : Fibroblast growth factor 23 (FGF-23), is recently discovered phosphaturic substance. It releases from bone osteocytes and plays a key role in the physiological regulation of phosphate metabolism. Excessive action of FGF23 results in several hypophosphatemic diseases characterized by impaired renal tubular phosphate reabsorption. In contrast, deficient action of FGF23 causes familial ...

Endocrine and Paracrine Role of FGF23 and Klotho in Health and Disease

Endocrine and Paracrine Role of FGF23 and Klotho in Health and Disease
  • Author : Reinhold G. Erben,L. Darryl Quarles
  • Publisher : Frontiers Media SA
  • Release Date : 2019-04-05
  • Total pages : 212
  • ISBN : 0128180374
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Summary : αKlotho and fibroblast growth factor-23 (FGF23) were discovered independently about 20 years ago. Since their initial description, a series of exciting discoveries have revealed the important role of endocrine and paracrine FGF23 and αKlotho signaling not only for the physiological regulation of mineral and bone homeostasis, but also for the pathophysiology ...

Fibroblast Growth Factor 23 Induces Left Ventricular Hypertrophy

Fibroblast Growth Factor 23 Induces Left Ventricular Hypertrophy
  • Author : Ansel Philip Amaral
  • Publisher : Unknown
  • Release Date : 2012
  • Total pages : 212
  • ISBN : 0128180374
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Summary : Over one in ten adults manifests physiological evidence of chronic kidney disease (CKD), which significantly reduces life expectancy due to cardiovascular complications. Left ventricular hypertrophy (LVH) is at the center of this relationship and up to 90% of patients with CKD also manifest LVH. Fibroblast growth factor (FGF) 23 is a phosphorus-regulating ...

Fibroblast Growth Factor 23 a Bridge Between Bone Minerals and Renal Volume Handling

Fibroblast Growth Factor 23  a Bridge Between Bone Minerals and Renal Volume Handling
  • Author : Jelmer Kor Humalda
  • Publisher : Unknown
  • Release Date : 2016
  • Total pages : 212
  • ISBN : 0128180374
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Summary : Download or read online Fibroblast Growth Factor 23 a Bridge Between Bone Minerals and Renal Volume Handling written by Jelmer Kor Humalda, published by which was released on 2016. Get Fibroblast Growth Factor 23 a Bridge Between Bone Minerals and Renal Volume Handling Books now! Available in PDF, ePub and Kindle....

Studies on the Regulation of the Phosphaturic Hormone Fibroblast Growth Factor 23 FGF23

Studies on the Regulation of the Phosphaturic Hormone Fibroblast Growth Factor 23  FGF23
  • Author : Ludmilla Bär
  • Publisher : Unknown
  • Release Date : 2019
  • Total pages : 212
  • ISBN : 0128180374
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Summary : Download or read online Studies on the Regulation of the Phosphaturic Hormone Fibroblast Growth Factor 23 FGF23 written by Ludmilla Bär, published by which was released on 2019. Get Studies on the Regulation of the Phosphaturic Hormone Fibroblast Growth Factor 23 FGF23 Books now! Available in PDF, ePub and Kindle....

Fibroblast Growth Factor 23 and Sudden Versus Non sudden Cardiac Death

Fibroblast Growth Factor 23 and Sudden Versus Non sudden Cardiac Death
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 7
  • ISBN : 0128180374
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Summary : BACKGROUND: Elevated fibroblast growth factor 23 (FGF-23) concentrations are associated with greater risk of cardiovascular events and mortality, especially among people with chronic kidney disease (CKD). Because individuals with CKD are at an increased risk of sudden cardiac death (SCD), we sought to understand whether FGF-23 level is a stronger risk ...

Phosphate and Vitamin D in Chronic Kidney Disease

Phosphate and Vitamin D in Chronic Kidney Disease
  • Author : M.S. Razzaque
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2013-05-02
  • Total pages : 162
  • ISBN : 0128180374
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Summary : The enormous progress made during the last decade has resulted in a better conceptual understanding of mineral ion metabolism in general. With regard to chronic kidney disease, the two most affected nutrients are phosphate and vitamin D. This book provides an overview of the physiological aspects of phosphate and vitamin ...

The Vitamin D Fibroblast Growth Factor 23 Klotho Axis and Progression of Chronic Kidney Disease

The Vitamin D     Fibroblast Growth Factor 23     Klotho Axis and Progression of Chronic Kidney Disease
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2017
  • Total pages : 134
  • ISBN : 0128180374
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Summary : Download or read online The Vitamin D Fibroblast Growth Factor 23 Klotho Axis and Progression of Chronic Kidney Disease written by , published by which was released on 2017. Get The Vitamin D Fibroblast Growth Factor 23 Klotho Axis and Progression of Chronic Kidney Disease Books now! Available in PDF, ePub and Kindle....

Identification of Novel Regulators of Fibroblast Growth Factor 23 FGF23 Production

Identification of Novel Regulators of Fibroblast Growth Factor 23  FGF23  Production
  • Author : Philipp Glosse
  • Publisher : Unknown
  • Release Date : 2020*
  • Total pages : 212
  • ISBN : 0128180374
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Summary : FGF23; Klotho; kidney; calcium; phosphate; Orai1; inflammation; energy deficiency....

Endocrine FGFs and Klothos

Endocrine FGFs and Klothos
  • Author : Makoto Kuro-o
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-03-06
  • Total pages : 210
  • ISBN : 0128180374
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Summary : Fibroblast growth factors (FGFs) have been recognized primarily as autocrine/paracrine factors that regulate embryonic development and organogenesis. However, recent studies have revealed that some FGFs function as endocrine factors and regulate various metabolic processes in adulthood. Such FGFs, collectively called endocrine FGFs, are comprised of three members (FGF15/19, FGF21, ...

Fibroblast Growth Factor 23 Directly Targets Hepatocytes to Promote Inflammation in Chronic Kidney Disease

Fibroblast Growth Factor 23 Directly Targets Hepatocytes to Promote Inflammation in Chronic Kidney Disease
  • Author : Saurav Singh
  • Publisher : Unknown
  • Release Date : 2016
  • Total pages : 212
  • ISBN : 0128180374
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Summary : Chronic kidney disease (CKD) is a global health problem that affects 10-15% of the adult population worldwide and significantly increases the risk of death. Patients with CKD develop marked elevations in circulating levels of the phosphaturic hormone, fibroblast growth factor 23 (FGF23), which correlate with the stage of disease, and are ...

The Regulation of Fibroblast Growth Factor 23 in Autosomal Dominant Polycystic Kidney Disease

The Regulation of Fibroblast Growth Factor 23 in Autosomal Dominant Polycystic Kidney Disease
  • Author : Daniela Spichtig
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 212
  • ISBN : 0128180374
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Summary : Download or read online The Regulation of Fibroblast Growth Factor 23 in Autosomal Dominant Polycystic Kidney Disease written by Daniela Spichtig, published by which was released on 2015. Get The Regulation of Fibroblast Growth Factor 23 in Autosomal Dominant Polycystic Kidney Disease Books now! Available in PDF, ePub and Kindle....