Epigenetics of Chronic Pain

Written By Anonim
Epigenetics of Chronic Pain
  • Publsiher : Academic Press
  • Release : 29 October 2018
  • ISBN : 0128140712
  • Pages : 248 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Epigenetics of Chronic Pain written by Anonim which was release on 29 October 2018, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Epigenetics of Chronic Pain, Volume Nine, presents comprehensive information on the role of epigenetics in chronic pain sensitivity, providing a detailed, but accessible, view of the field from basic principles, to clinical application. Leading international researchers discuss essential mechanisms of chronic pain epigenetics, including the molecular processes of chromatin remodeling, histone modifications, and the microRNAs and noncoding RNAs involved in regulating genes tied to pain sensitivity. The influence of epigenetics in inflammatory, neuropathic, visceral and other pain models is examined, with data derived from epigenetic studies on peripheral and central mechanisms of pain sensitivity in animal models and clinical cases studies. The studies and case examples cited highlight therapeutic pathways of significance and next steps for researchers to develop epigenetic-based treatments for chronic pain. In recent years, epigenetic regulation of gene expression has been shown to play a central role in managing human pain sensitivity. Findings show that expression of many genes critical to increases or decreases in pain sensitivity are indeed regulated by DNA methylation and its enzymes, histone-involved chromatin remodeling, and noncoding RNAs, mainly microRNAs. Compiles all known information on epigenetic regulation of chronic pain in one volume Covers the basic functionality of epigenetic mechanisms involved in pain management, applications of recent research in understanding different types of chronic pain, and pathways for developing therapeutics Leading international researchers from across academia, clinical settings, and the pharmaceutical industry discuss epigenetics in inflammatory, neuropathic, visceral, and other pain models in-depth Enables clinicians, researchers, and pharmacologists to better understand and treat chronic pain

Epigenetics of Chronic Pain

Epigenetics of Chronic Pain
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2018-10-29
  • Total pages : 248
  • ISBN : 0128140712
GET BOOK

Summary : Epigenetics of Chronic Pain, Volume Nine, presents comprehensive information on the role of epigenetics in chronic pain sensitivity, providing a detailed, but accessible, view of the field from basic principles, to clinical application. Leading international researchers discuss essential mechanisms of chronic pain epigenetics, including the molecular processes of chromatin remodeling, ...

Role of Epigenetic Modification of Gene Expression in Chronic Pain

Role of Epigenetic Modification of Gene Expression in Chronic Pain
  • Author : 謝明君
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 212
  • ISBN : 0128140712
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Summary : Download or read online Role of Epigenetic Modification of Gene Expression in Chronic Pain written by 謝明君, published by which was released on 2018. Get Role of Epigenetic Modification of Gene Expression in Chronic Pain Books now! Available in PDF, ePub and Kindle....

Chronic Pain and DNA Methylation in the Mouse Prefrontal Cortex

Chronic Pain and DNA Methylation in the Mouse Prefrontal Cortex
  • Author : Lucas Topham
  • Publisher : Unknown
  • Release Date : 2021
  • Total pages : 212
  • ISBN : 0128140712
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Summary : "Chronic pain is one of the leading causes of disability and reduced quality of life worldwide. As a result of chronic pain, the prefrontal cortex (PFC) undergoes significant structural and functional remodeling, resulting in the loss of grey matter, altered synapse formation, and changes in neurotransmitter and ion channel signalling. ...

Translating Epigenetics to the Clinic

Translating Epigenetics to the Clinic
  • Author : Jeffrey Laurence
  • Publisher : Academic Press
  • Release Date : 2016-12-30
  • Total pages : 324
  • ISBN : 0128140712
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Summary : Translating Epigenetics to the Clinic reviews current methodological tools and experimental approaches used by leading translational researchers seeking to use epigenetics as a clinical model. It organizes epigenetics into disease treatment areas with a major focus on oncology, and with much coverage of pervasive treatment categories such as diabetes, as ...

Chronic Pain New Insights for the Healthcare Professional 2013 Edition

Chronic Pain  New Insights for the Healthcare Professional  2013 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2013-07-22
  • Total pages : 193
  • ISBN : 0128140712
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Summary : Chronic Pain: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Additional Research. The editors have built Chronic Pain: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional ...

Genomic Adaptation to Disease

Genomic Adaptation to Disease
  • Author : Sebastian Alvarado
  • Publisher : Unknown
  • Release Date : 2013
  • Total pages : 212
  • ISBN : 0128140712
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Summary : "Cancer and chronic pain are two common pathologies affecting millions of patients worldwide. Much like most other disease states, they can be determined genetically, environmentally, or both. Unlike the static genome, the epigenome is responsible for interpreting environmental interactions and is often altered in disease states. A subset of epigenetic ...

Neurobiological Mechanisms Involved in Chronic Pain

Neurobiological Mechanisms Involved in Chronic Pain
  • Author : Roger Negrete Buela
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 356
  • ISBN : 0128140712
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Summary : Chronic pain is currently a major clinical issue that represents huge economic and social burdens. Chronic pain treatment currently available presents limited efficacy and significant side effects. One of the reasons for this lack of effective therapeutic approaches is the insufficient knowledge of the mechanisms involved in the development and ...

Molecular and Cell Biology of Pain

Molecular and Cell Biology of Pain
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2015-03-02
  • Total pages : 648
  • ISBN : 0128140712
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Summary : Pain is the number one reason that people seek medical attention but pain is still under- and poorly-treated world-wide. The purpose of this book is to give an up to date picture of what causes pain, how pain becomes chronic and what pharmacological targets might be manipulated to alleviate acute ...

Personalized Epigenetics

Personalized Epigenetics
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release Date : 2015-04-28
  • Total pages : 610
  • ISBN : 0128140712
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Summary : Personalized Epigenetics discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures that can guide both disorder and disease prevention and therapy. The book details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, and ...

Pain Management An Issue of Anesthesiology Clinics E Book

Pain Management  An Issue of Anesthesiology Clinics  E Book
  • Author : Perry G. Fine,Michael A. Ashburn
  • Publisher : Elsevier Health Sciences
  • Release Date : 2016-07-06
  • Total pages : 212
  • ISBN : 0128140712
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Summary : This issue of Anesthesiology Clinics focuses on Pain Management.Topics will include: The Pain Treatment Imperative: Developments in the 21st Century, Imaging Pain, The Opioid Conundrum, Advancing the Pain Agenda in the Veteran Population ,Interventional Treatments of Cancer Pain, Integrating Pain Care into the Peri-Operative Surgical Home, Pain Care in ...

An Introduction to Pain and its relation to Nervous System Disorders

An Introduction to Pain and its relation to Nervous System Disorders
  • Author : Anna A. Battaglia
  • Publisher : John Wiley & Sons
  • Release Date : 2016-05-02
  • Total pages : 440
  • ISBN : 0128140712
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Summary : Introduction to Pain and its relation to Nervous System Disorders provides an accessible overview of the latest developments in the science underpinning pain research, including, but not limited to, the physiological, pathological and psychological aspects. This unique book fills a gap in current literature by focussing on the intricate relationship ...

The Epigenetics of Autoimmunity

The Epigenetics of Autoimmunity
  • Author : Rongxin Zhang
  • Publisher : Academic Press
  • Release Date : 2018-04-25
  • Total pages : 432
  • ISBN : 0128140712
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Summary : The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic ...

Conquer Your Chronic Pain

Conquer Your Chronic Pain
  • Author : Peter Abaci
  • Publisher : Red Wheel/Weiser
  • Release Date : 2016-05-23
  • Total pages : 192
  • ISBN : 0128140712
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Summary : An “empowering guide on how to win the battle against chronic pain and put an end to America’s epidemic of pain killer addiction.”—Vijay B. Vad, MD, author of Back Rx Conquer Your Chronic Pain offers the millions of chronic-pain sufferers throughout the world a transformative model for pain ...

Overlapping Pain and Psychiatric Syndromes

Overlapping Pain and Psychiatric Syndromes
  • Author : Mario Incayawar,Sioui Maldonado Bouchard,Michael R. Clark
  • Publisher : Oxford University Press, USA
  • Release Date : 2020-09-09
  • Total pages : 456
  • ISBN : 0128140712
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Summary : This book describes the complex and striking relationships between pain and psychiatric disorders, offering an in-depth review of the challenging and neglected intersection between pain medicine and psychiatry....

Epigenetics Methods

Epigenetics Methods
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release Date : 2020-07-08
  • Total pages : 736
  • ISBN : 0128140712
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Summary : In recent years, the field of epigenetics has grown significantly, driving new understanding of human developmental processes and disease expression, as well as advances in diagnostics and therapeutics. As the field of epigenetics continues to grow, methods and technologies have multiplied, resulting in a wide range of approaches and tools ...