Epigenetics in Human Disease

Written By Trygve Tollefsbol
Epigenetics in Human Disease
  • Publsiher : Academic Press
  • Release : 01 June 2018
  • ISBN : 9780128122150
  • Pages : 704 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Epigenetics in Human Disease written by Trygve Tollefsbol which was release on 01 June 2018, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Epigenetics is one of the fastest growing fields in biomedical research, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. In Epigenetics in Human Disease, Second Edition, leading international researchers examine those diseases or conditions for which we have advanced knowledge of epigenetic mechanisms such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders, and cardiovascular disease. In addition to detailing the role of epigenetics in the etiology, progression, diagnosis, and prognosis of these diseases, novel epigenetic approaches to treatment are also explored. Fully revised and up-to-date, this new edition discusses topics of current interest in epigenetic research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, epigenetic mechanisms of imprinting disorders, online epigenetic tools and data sets, early-life programming of epigenetics in age-related diseases, and epigenetics of addiction and suicide, as well as epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer's disease, respiratory diseases, and many other human maladies. With its translational focus, Epigenetics in Human Disease, Second Edition, serves as an invaluable reference for both basic scientists and clinicians alike Includes contributions by leading international investigators involved in translational epigenetic research and therapeutic applications Integrates methods and applications with fundamental chapters on epigenetics in human disease, as well as evaluation of recent epigenetic clinical breakthroughs Side-by-side coverage of the basis of epigenetic diseases and treatment pathways This new edition has been fully revised to cover current developments in disease epigenetics, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, epigenetic mechanisms of imprinting disorders, online epigenetic tools and data sets, early-life programming of epigenetics in age-related diseases, and epigenetics of addiction and suicide, as well as epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer's disease, respiratory diseases, and many other human maladies

Epigenetics in Human Disease

Epigenetics in Human Disease
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release Date : 2018-06
  • Total pages : 704
  • ISBN : 9780128122150
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Summary : Epigenetics is one of the fastest growing fields in biomedical research, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. In Epigenetics in Human Disease, Second Edition, leading international researchers examine those diseases or conditions for which we ...

Epigenetics in Human Disease

Epigenetics in Human Disease
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release Date : 2012-07-26
  • Total pages : 592
  • ISBN : 9780128122150
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Summary : Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of ...

Computational Epigenetics and Diseases

Computational Epigenetics and Diseases
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-02-06
  • Total pages : 450
  • ISBN : 9780128122150
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Summary : Computational Epigenetics and Diseases, written by leading scientists in this evolving field, provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases. In particular, the major computational tools, databases, and strategies for computational epigenetics analysis, for example, DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA, are summarized, ...

Computational Epigenetics in Human Diseases Cell Differentiation and Cell Reprogramming Volume I

Computational Epigenetics in Human Diseases  Cell Differentiation  and Cell Reprogramming  Volume I
  • Author : Jianzhong Su,Meng Zhou,Yongchun Zuo,Xiaotian Zhang
  • Publisher : Frontiers Media SA
  • Release Date : 2021-02-24
  • Total pages : 212
  • ISBN : 9780128122150
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Summary : Download or read online Computational Epigenetics in Human Diseases Cell Differentiation and Cell Reprogramming Volume I written by Jianzhong Su,Meng Zhou,Yongchun Zuo,Xiaotian Zhang, published by Frontiers Media SA which was released on 2021-02-24. Get Computational Epigenetics in Human Diseases Cell Differentiation and Cell Reprogramming Volume I ...

Clinical Epigenetics

Clinical Epigenetics
  • Author : Luke B. Hesson,Antonia L. Pritchard
  • Publisher : Springer Nature
  • Release Date : 2019-08-31
  • Total pages : 265
  • ISBN : 9780128122150
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Summary : In genetic pathology, epigenetic testing is rare and under utilised. In this book, we introduce epigenetics to a non-expert scientific audience and describe current and future clinical utility of epigenetic testing. By focussing on epigenetics in human disease this book will guide professionals (scientists and clinicians) to understand how epigenetics ...

Transgenerational Epigenetics

Transgenerational Epigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-05-18
  • Total pages : 518
  • ISBN : 9780128122150
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Summary : Transgenerational Epigenetics, Second Edition, offers the only up-to-date, comprehensive analysis of the inheritance of epigenetic phenomena between generations with an emphasis on human disease relevance, drug discovery, and next steps in clinical translation. International experts discuss mechanisms of epigenetic inheritance, its expression in animal and plant models, and how human ...

Epigenetics and Complex Traits

Epigenetics and Complex Traits
  • Author : Anna K. Naumova,Celia M.T. Greenwood
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-09-17
  • Total pages : 341
  • ISBN : 9780128122150
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Summary : This book will provide an overview of basic epigenetic phenomena; interaction between epigenetic and genetic factors; and the influence of epigenetic factors on inheritance. Epigenetic states may contribute to the penetrance of genetic polymorphisms or mutations and thereby modify inheritance patterns. This may result in non‐Mendelian inheritance of genetic ...

Human Epigenetics How Science Works

Human Epigenetics  How Science Works
  • Author : Carsten Carlberg,Ferdinand Molnár
  • Publisher : Springer
  • Release Date : 2019-10-05
  • Total pages : 153
  • ISBN : 9780128122150
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Summary : The view “It’s all in our genes and we cannot change it” developed in the past 150 years since Gregor Mendel’s experiments with flowering pea plants. However, there is a special form of genetics, referred to as epigenetics, which does not involve any change of our genes but regulates ...

DNA Methylation and Complex Human Disease

DNA Methylation and Complex Human Disease
  • Author : Michel Neidhart
  • Publisher : Academic Press
  • Release Date : 2015-08-11
  • Total pages : 552
  • ISBN : 9780128122150
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Summary : DNA Methylation and Complex Human Disease reviews the possibilities of methyl-group-based epigenetic biomarkers of major diseases, tailored epigenetic therapies, and the future uses of high-throughput methylome technologies. This volume includes many pertinent advances in disease-bearing research, including obesity, type II diabetes, schizophrenia, and autoimmunity. DNA methylation is also discussed as ...

Genetics and Epigenetics of Repeat Derepression in Human Disease

Genetics and Epigenetics of Repeat Derepression in Human Disease
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2016
  • Total pages : 182
  • ISBN : 9780128122150
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Summary : Download or read online Genetics and Epigenetics of Repeat Derepression in Human Disease written by , published by which was released on 2016. Get Genetics and Epigenetics of Repeat Derepression in Human Disease Books now! Available in PDF, ePub and Kindle....

Epigenetics of Infectious Diseases

Epigenetics of Infectious Diseases
  • Author : Walter Doerfler,Josep Casadesús
  • Publisher : Springer
  • Release Date : 2017-06-24
  • Total pages : 277
  • ISBN : 9780128122150
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Summary : The present volume of Epigenetics and Human Health is devoted to the patho-epigenetics of viral and microbial infections, an exiting new field of disease-related epigenetic research. As recognized during the past years, epigenetic reprogramming of pathogen and host genome functions – the latter frequently induced by pathogens – plays an important role ...

Epigenetics In Human Reproduction And Development

Epigenetics In Human Reproduction And Development
  • Author : Naumova Anna K,Taketo-hosotani Teruko
  • Publisher : World Scientific
  • Release Date : 2016-12-20
  • Total pages : 304
  • ISBN : 9780128122150
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Summary : Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from ...

Nutrition Epigenetic Mechanisms and Human Disease

Nutrition  Epigenetic Mechanisms  and Human Disease
  • Author : Nilanjana Maulik,Gautam Maulik
  • Publisher : CRC Press
  • Release Date : 2010-12-03
  • Total pages : 442
  • ISBN : 9780128122150
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Summary : As nutrition research is shifting its focus from epidemiology and physiology to effects of nutrients at the molecular level, a uniquely tailored diet that corresponds to the demands of our genetic signature is emerging as an indispensable need. Using high-throughput genomic tools, nutrigenomics unravels the influence of micro- and macronutrients ...

Ageing and Senescence

Ageing and Senescence
  • Author : Muralidhar S. Talkad,Akanksha Rai,Sneha Srivathasava
  • Publisher : LAP Lambert Academic Publishing
  • Release Date : 2014-02-24
  • Total pages : 184
  • ISBN : 9780128122150
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Summary : Molecular genetics - with biotechnological tools, metabolic engineering, and disease diagnosis with pathophysiology in which there is a considerable enthusiasm driving new discoveries. Epigenomes would serve as a reference for comparison with diseased tissues, revealing epigenetic causes of disease. The importance of epigenetics in human disease, together with the maturing ...

Epigenetics Development and Disease

Epigenetics  Development and Disease
  • Author : Tapas Kumar Kundu
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-11-13
  • Total pages : 689
  • ISBN : 9780128122150
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Summary : Epigenetics fine-tunes the life processes dictated by DNA sequences, but also kick-starts pathophysiological processes including diabetes, AIDS and cancer. This volume tracks the latest research on epigenetics, including work on new-generation therapeutics....