Epigenetic Gene Expression and Regulation

Written By Suming Huang
Epigenetic Gene Expression and Regulation
  • Publsiher : Academic Press
  • Release : 19 October 2015
  • ISBN : 0128004711
  • Pages : 482 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Epigenetic Gene Expression and Regulation written by Suming Huang which was release on 19 October 2015, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples. Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies Helps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspring Chapters are replete with clinical examples to empower the basic biology with translational significance Offers more than 100 illustrations to distill key concepts and decipher complex science

Epigenetic Gene Expression and Regulation

Epigenetic Gene Expression and Regulation
  • Author : Suming Huang,Michael D Litt,C. Ann Blakey
  • Publisher : Academic Press
  • Release Date : 2015-10-19
  • Total pages : 482
  • ISBN : 0128004711
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Summary : Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can ...

Epigenetic Mechanisms of Gene Regulation

Epigenetic Mechanisms of Gene Regulation
  • Author : Vincenzo E. A. Russo,Robert A. Martienssen,Arthur D. Riggs
  • Publisher : Unknown
  • Release Date : 1996
  • Total pages : 692
  • ISBN : 0128004711
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Summary : Many inheritable changes in gene function are not explained by changes in the DNA sequence. Such epigenetic mechanisms are known to influence gene function in most complex organisms and include effects such as transposon function, chromosome imprinting, yeast mating type switching and telomeric silencing. In recent years, epigenetic effects have ...

Non coding RNAs and Epigenetic Regulation of Gene Expression

Non coding RNAs and Epigenetic Regulation of Gene Expression
  • Author : Kevin V. Morris
  • Publisher : Horizon Scientific Press
  • Release Date : 2012
  • Total pages : 216
  • ISBN : 0128004711
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Summary : Non-coding RNAs potentially play an active role in modulating gene transcription and epigenetic states. Several genes in differentiated cells may be under some form of RNA-based transcriptional and epigenetic regulatory control. This form of regulation may be controlled by selective pressures and influence the adaptability of the cell. The concept ...

Deciphering the Gene Expression Control in Epigenetic Post transcriptional and Translational Regulation

Deciphering the Gene Expression Control in Epigenetic  Post transcriptional and Translational Regulation
  • Author : Jianan Lin
  • Publisher : Unknown
  • Release Date : 2019
  • Total pages : 212
  • ISBN : 0128004711
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Summary : Regulation of gene expression, through which cells increase or decrease the gene products, is an essential part of development, which not only determines the cellular differentiation but also responds to the environmental changes. A wide range of gene regulation mechanisms are involved in two major processes, from Deoxyribonucleic acid (DNA) ...

Gene Expression and Regulation in Mammalian Cells

Gene Expression and Regulation in Mammalian Cells
  • Author : Fumiaki Uchiumi
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-02-21
  • Total pages : 334
  • ISBN : 0128004711
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Summary : "Central dogma" was presented by Dr. Francis Crick 60 years ago. The information of nucleotide sequences on DNAs is transcribed into RNAs by RNA polymerases. We learned the mechanisms of how transcription determines function of proteins and behaviour of cells and even how it brings appearances of organisms. This book is ...

Chromatin and Gene Regulation

Chromatin and Gene Regulation
  • Author : Bryan M. Turner
  • Publisher : John Wiley & Sons
  • Release Date : 2008-04-15
  • Total pages : 288
  • ISBN : 0128004711
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Summary : Written in an informal and accessible style, Chromatin and Gene Regulation enables the reader to understand the science of this rapidly moving field. Chromatin is a fundamental component in the network of controls that regulates gene expression. Many human diseases have been linked to disruption of these control processes by ...

Epigenetic Modifications and Viral Infections

Epigenetic Modifications and Viral Infections
  • Author : Silvia Carolina Galvan,Alejandro García Carrancá,Félix Recillas-Targa,Jiuzhou Song
  • Publisher : Frontiers Media SA
  • Release Date : 2015-07-09
  • Total pages : 212
  • ISBN : 0128004711
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Summary : Epigenetics is defined as the study of modifications of the genome, heritable during cell division that does not involve changes in DNA sequences. Up to date, epigenetic modifications involve at least three general mechanisms regulating gene expression: histone modifications, DNA methylation, and non-coding RNAs (ncRNAs). For the past two decades, ...

Epigenetic Gene Regulation in Stem Cell Differentiation and Reprogramming

Epigenetic Gene Regulation in Stem Cell Differentiation and Reprogramming
  • Author : Kevin Huang
  • Publisher : Unknown
  • Release Date : 2013
  • Total pages : 223
  • ISBN : 0128004711
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Summary : The regulatory capacities of epigenetic mechanisms including DNA methylation, histone modifications, and non-coding RNAs, have seen a rising interest in recent years. These epigenetic marks are pervasive and non-randomly distributed across the genome, raising intriguing questions on how epigenetics contributes to genomic features that define cellular identity and function. Unlike ...

Recent Advances of Epigenetics in Crop Biotechnology

Recent Advances of Epigenetics in Crop Biotechnology
  • Author : Clelia De-la-Peña,Raúl Alvarez-Venegas,Christopher Cullis
  • Publisher : Frontiers Media SA
  • Release Date : 2016-05-31
  • Total pages : 212
  • ISBN : 0128004711
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Summary : Epigenetics is a new field that explains gene expression at the chromatin structure and organization level. Three principal epigenetic mechanisms are known and hundreds of combinations among them can develop different phenotypic characteristics. DNA methylation, histone modifications and small RNAs have been identified, and their functions are being studied in ...

Gene Expression and Regulation in Mammalian Cells

Gene Expression and Regulation in Mammalian Cells
  • Author : Fumiaki Uchiumi
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-02-28
  • Total pages : 372
  • ISBN : 0128004711
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Summary : Sixty years after the "central dogma," great achievements have been developed in molecular biology. We have also learned the important functions of noncoding RNAs and epigenetic regulations. More importantly, whole genome sequencing and transcriptome analyses enabled us to diagnose specific diseases. This book is not only intended for students and ...

A Systems Biology Approach to Epigenetic Gene Regulation

A Systems Biology Approach to Epigenetic Gene Regulation
  • Author : Stephen Patrick Wilson
  • Publisher : Unknown
  • Release Date : 2019
  • Total pages : 262
  • ISBN : 0128004711
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Summary : The ability to control when, and how much of the genetic code is being expressed is the underlying principle behind gene regulation. Control of gene production is able to influence a cell's phenotype by determining which structural components of the cell's observable traits (shape, growth, and behavior) are made. In ...

Gene Regulation Epigenetics and Hormone Signaling

Gene Regulation  Epigenetics and Hormone Signaling
  • Author : Subhrangsu S. Mandal
  • Publisher : John Wiley & Sons
  • Release Date : 2017-10-23
  • Total pages : 668
  • ISBN : 0128004711
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Summary : The first of its kind, this reference gives a comprehensive but concise introduction to epigenetics before covering the many interactions between hormone regulation and epigenetics at all levels. The contents are very well structured with no overlaps between chapters, and each one features supplementary material for use in presentations. Throughout, ...

Epigenetics

Epigenetics
  • Author : Reinhard Heil,Stefanie B. Seitz,Harald König,Jürgen Robienski
  • Publisher : Springer
  • Release Date : 2017-01-31
  • Total pages : 200
  • ISBN : 0128004711
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Summary : Modern epigenetics unites scientists from life sciences, organic chemistry as well as computer and engineering sciences to find an answer to the question of how environmental influences can have a lasting effect on gene expression, maybe even into the next generations. This volume examines from an interdisciplinary perspective the ethical, ...

Epigenetics and Disease

Epigenetics and Disease
  • Author : Susan M. Gasser,En Li
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-10-17
  • Total pages : 270
  • ISBN : 0128004711
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Summary : Epigenetics has emerged recently as an important area of molecular biological studies. Epigenetic modifications lead to potentially heritable but reversible alterations in the expression of genes that determine cell fate. Epigenetic misregulation is thus often linked to degenerative diseases, cancer and neuronal disorders. Recent biomedical interest in this regulatory system ...

Introduction to Genetics

Introduction to Genetics
  • Author : Jun Wan
  • Publisher : CreateSpace
  • Release Date : 2013-07-20
  • Total pages : 270
  • ISBN : 0128004711
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Summary : DNA methylation is the modification of DNA molecule, transferring methy group to the 5th position of the cytosine pyrimidine ring. This biochemical process plays a crucial role in many cellular processes of higher organisms. For example, people have found distinct patterns of DNA methylation during cellular differentiation and tissue development. ...