Cardiac Energy Metabolism in Health and Disease

Written By Gary D. Lopaschuk
Cardiac Energy Metabolism in Health and Disease
  • Publsiher : Springer
  • Release : 22 August 2014
  • ISBN : 1493912275
  • Pages : 295 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Cardiac Energy Metabolism in Health and Disease written by Gary D. Lopaschuk which was release on 22 August 2014, this book published by Springer. Available in PDF, EPUB and Kindle Format. Book excerpt: The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac function. It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease. It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease. Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional and physiological levels. It also describes how alterations in energy metabolism contribute to the development of heart dysfunction and how optimization of energy metabolism can be used to treat heart disease. The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics. The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists, pharmacologists, cardiologists, cardiovascular surgeons and other health professionals.

Cardiac Energy Metabolism in Health and Disease

Cardiac Energy Metabolism in Health and Disease
  • Author : Gary D. Lopaschuk,Naranjan S. Dhalla
  • Publisher : Springer
  • Release Date : 2014-08-22
  • Total pages : 295
  • ISBN : 1493912275
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Summary : The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change ...

Cardiac Energy Metabolism in Heart Failure

Cardiac Energy Metabolism in Heart Failure
  • Author : Society for Heart and Vascular Metabolism
  • Publisher : Unknown
  • Release Date : 2006
  • Total pages : 212
  • ISBN : 1493912275
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Summary : Download or read online Cardiac Energy Metabolism in Heart Failure written by Society for Heart and Vascular Metabolism, published by which was released on 2006. Get Cardiac Energy Metabolism in Heart Failure Books now! Available in PDF, ePub and Kindle....

Special Issue

Special Issue
  • Author : William C. Stanley
  • Publisher : Unknown
  • Release Date : 2002
  • Total pages : 212
  • ISBN : 1493912275
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Summary : Download or read online Special Issue written by William C. Stanley, published by which was released on 2002. Get Special Issue Books now! Available in PDF, ePub and Kindle....

Cardiac Energy Metabolism in Heart Failure and Metabolic Disease

Cardiac Energy Metabolism in Heart Failure and Metabolic Disease
  • Author : William C. Stanley
  • Publisher : Academic Press
  • Release Date : 2016-01-12
  • Total pages : 384
  • ISBN : 1493912275
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Summary : Cardiac Energy Metabolism in Heart Failure and Metabolic Disease...

Novel Concepts in Cardiac Energy Metabolism From Biology to Disease

Novel Concepts in Cardiac Energy Metabolism  From Biology to Disease
  • Author : Thomas Pulinilkunnil,Petra Kienesberger,Jeevan Nagendran
  • Publisher : Frontiers Media SA
  • Release Date : 2019-08-08
  • Total pages : 89
  • ISBN : 1493912275
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Summary : Download or read online Novel Concepts in Cardiac Energy Metabolism From Biology to Disease written by Thomas Pulinilkunnil,Petra Kienesberger,Jeevan Nagendran, published by Frontiers Media SA which was released on 2019-08-08. Get Novel Concepts in Cardiac Energy Metabolism From Biology to Disease Books now! Available in PDF, ePub ...

The Sinatra Solution

The Sinatra Solution
  • Author : Stephen T. Sinatra, M.D.
  • Publisher : ReadHowYouWant.com
  • Release Date : 2009-04-24
  • Total pages : 512
  • ISBN : 1493912275
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Summary : Board-certified cardiologist Dr. Stephen T. Sinatra discusses the importance of energy metabolism on cardiovascular health and the positive impact these three energy-supplying nutrients have on the cardiovascular system. He guides you through the basics of energy metabolism and cardiac bioenergetics, and clearly explains the role of coenzyme Q10, L-carnitine, and ...

Metabolic Efficiency in Remodeled Failing Hearts

Metabolic Efficiency in Remodeled Failing Hearts
  • Author : Waleed Gameel Tawfeek Masoud
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 280
  • ISBN : 1493912275
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Summary : Heart failure is a serious cardiovascular disease that develops following a variety of insults to the heart including hypertrophy and myocardial infarction. While it is clear that heart failure is associated with changes in cardiac energy metabolism, it remains unclear if, and how, such changes might contribute to left ventricular (...

The Sinatra Solution

The Sinatra Solution
  • Author : Stephen T. Sinatra, M.D.
  • Publisher : ReadHowYouWant.com
  • Release Date : 2009-04-24
  • Total pages : 520
  • ISBN : 1493912275
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Summary : Board-certified cardiologist Dr. Stephen T. Sinatra discusses the importance of energy metabolism on cardiovascular health and the positive impact these three energy-supplying nutrients have on the cardiovascular system. He guides you through the basics of energy metabolism and cardiac bioenergetics, and clearly explains the role of coenzyme Q10, L-carnitine, and ...

The Sinatra Solution

The Sinatra Solution
  • Author : Stephen T. Sinatra, M.D.
  • Publisher : ReadHowYouWant.com
  • Release Date : 2009-04-24
  • Total pages : 320
  • ISBN : 1493912275
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Summary : Board-certified cardiologist Dr. Stephen T. Sinatra discusses the importance of energy metabolism on cardiovascular health and the positive impact these three energy-supplying nutrients have on the cardiovascular system. He guides you through the basics of energy metabolism and cardiac bioenergetics, and clearly explains the role of coenzyme Q10, L-carnitine, and ...

Energy Metabolism in Heart Failure

Energy Metabolism in Heart Failure
  • Author : HOWARD J. EISEN
  • Publisher : Academic Press
  • Release Date : 2018-06-01
  • Total pages : 256
  • ISBN : 1493912275
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Summary : Energy Metabolism in Heart Failure...

Metabolisme Energetique Cardiaque Et Maladie Coronaire Du Patient Diabetique

Metabolisme Energetique Cardiaque Et Maladie Coronaire Du Patient Diabetique
  • Author : Association de langue française pour l'étude du diabète et des maladies métaboliques,Biopharma
  • Publisher : Unknown
  • Release Date : 2001
  • Total pages : 1
  • ISBN : 1493912275
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Summary : Download or read online Metabolisme Energetique Cardiaque Et Maladie Coronaire Du Patient Diabetique written by Association de langue française pour l'étude du diabète et des maladies métaboliques,Biopharma, published by which was released on 2001. Get Metabolisme Energetique Cardiaque Et Maladie Coronaire Du Patient Diabetique Books now! ...

The Role of Cardiac Energy Metabolism During Stress in Hypertrophic and Dilated Cardiomyopathy

The Role of Cardiac Energy Metabolism During Stress in Hypertrophic and Dilated Cardiomyopathy
  • Author : Sairia Dass
  • Publisher : Unknown
  • Release Date : 2011
  • Total pages : 212
  • ISBN : 1493912275
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Summary : Both hypertrophic (HCM) and dilated cardiomyopathy (DCM), though differing in their etiologies, share features of impaired resting energetics. The aim of this thesis was to determine if cardiac high energy phosphate metabolism, measured as the phosphocreatine (PCr)/ ATP ratio using 31Phosphorus magnetic resonance spectroscopy (31p MRS), is further impaired during ...

The Role of Energy Metabolism Defects in Cardiomyopathy

The Role of Energy Metabolism Defects in Cardiomyopathy
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2000
  • Total pages : 2
  • ISBN : 1493912275
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Summary : Download or read online The Role of Energy Metabolism Defects in Cardiomyopathy written by , published by which was released on 2000. Get The Role of Energy Metabolism Defects in Cardiomyopathy Books now! Available in PDF, ePub and Kindle....

Inotropic Stimulation and Myocardial Energetics

Inotropic Stimulation and Myocardial Energetics
  • Author : H. Just,C. Holubarsch,H. Scholz
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-03-14
  • Total pages : 273
  • ISBN : 1493912275
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Summary : Inotropic stimulation of the myocardium, as well as vasodilation and diuresis as essential principles in the treatment of congestive heart failure have recently met with considerable criticism and reevaluation. It is generally agreed that unloading of the heart, either through vasodilation and/or diuresis, improves the working conditions of the ...

The Scientist s Guide to Cardiac Metabolism

The Scientist s Guide to Cardiac Metabolism
  • Author : Michael Schwarzer,Torsten Doenst
  • Publisher : Academic Press
  • Release Date : 2015-11-04
  • Total pages : 240
  • ISBN : 1493912275
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Summary : The Scientists Guide to Cardiac Metabolism combines the basic concepts of substrate metabolism, regulation, and interaction within the cell and the organism to provide a comprehensive introduction into the basics of cardiac metabolism. This important reference is the perfect tool for newcomers in cardiac metabolism, providing a basic understanding of ...