Drug Design and Discovery in Alzheimer s Disease

Written By Atta-ur-Rahman
Drug Design and Discovery in Alzheimer   s Disease
  • Publsiher : Elsevier
  • Release : 27 June 2015
  • ISBN : 0128039604
  • Pages : 784 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Drug Design and Discovery in Alzheimer s Disease written by Atta-ur-Rahman which was release on 27 June 2015, this book published by Elsevier. Available in PDF, EPUB and Kindle Format. Book excerpt: Drug Design and Discovery in Alzheimer’s Disease includes expert reviews of recent developments in Alzheimer's disease (AD) and neurodegenerative disease research. Originally published by Bentham as Frontiers in Drug Design and Discovery, Volume 6and now distributed by Elsevier, this compilation of the sixteen articles, written by leading global researchers, focuses on key developments in the understanding of the disease at molecular levels, identification and validation of molecular targets, as well as innovative approaches towards drug discovery, development, and delivery. Beginning with an overview of AD pharmacotherapy and existing blockbuster drugs, the reviews cover the potential of both natural and synthetic small molecules; the role of cholinesterases in the on-set and progression of AD and their inhibition; the role of beta-site APP clearing enzyme-1 (BACE-1) in the production of ß-amyloid proteins, one of the key reasons of the progression of AD; and other targets identified for AD drug discovery. Edited and written by leading experts in Alzheimer’s disease (AD) and other neurodegenerative disease drug development Describes existing drugs for AD and current molecular understanding of the condition Reviews recent advances in the field, including coverage of cholinesterases, BACE-1, and other drug development targets

Drug Design and Discovery in Alzheimer s Disease

Drug Design and Discovery in Alzheimer   s Disease
  • Author : Atta-ur-Rahman,Muhammad Iqbal Choudhary
  • Publisher : Elsevier
  • Release Date : 2015-06-27
  • Total pages : 784
  • ISBN : 0128039604
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Summary : Drug Design and Discovery in Alzheimer’s Disease includes expert reviews of recent developments in Alzheimer's disease (AD) and neurodegenerative disease research. Originally published by Bentham as Frontiers in Drug Design and Discovery, Volume 6and now distributed by Elsevier, this compilation of the sixteen articles, written by leading global researchers, ...

Textbook of Drug Design and Discovery Fifth Edition

Textbook of Drug Design and Discovery  Fifth Edition
  • Author : Kristian Stromgaard,Povl Krogsgaard-Larsen,Ulf Madsen
  • Publisher : CRC Press
  • Release Date : 2016-08-19
  • Total pages : 450
  • ISBN : 0128039604
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Summary : Building on the success of the previous editions, the Textbook of Drug Design and Discovery, Fifth Edition, has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The information is ...

Emerging Drugs and Targets for Alzheimer s Disease Beta amyloid tau protein and glucose metabolism

Emerging Drugs and Targets for Alzheimer s Disease  Beta amyloid  tau protein and glucose metabolism
  • Author : Ana Martínez
  • Publisher : Royal Society of Chemistry
  • Release Date : 2010
  • Total pages : 317
  • ISBN : 0128039604
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Summary : This volume describes the discovery and development history of the most promising drugs now in development for combating Alzheimer's disease....

Frontiers in CNS Drug Discovery

Frontiers in CNS Drug Discovery
  • Author : Atta-ur-Rahman,M. Iqbal Choudhary
  • Publisher : Bentham Science Publishers
  • Release Date : 2013-09-10
  • Total pages : 415
  • ISBN : 0128039604
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Summary : “Frontiers in CNS Drug Discovery” is an eBook series devoted to publishing the latest and the most important advances in Central Nervous System (CNS) drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, ...

Drug Design Principles and Applications

Drug Design  Principles and Applications
  • Author : Abhinav Grover
  • Publisher : Springer
  • Release Date : 2017-08-09
  • Total pages : 168
  • ISBN : 0128039604
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Summary : This book offers an in-depth discussion of the latest strategies in the field of drug design and their applications in various disorders, in order to encourage readers to undertake their own projects.It also includes the contemporary application of drug-designing methodologies to inspire others to further expand the utility of ...

BACE

BACE
  • Author : Varghese John
  • Publisher : John Wiley & Sons
  • Release Date : 2010-03-15
  • Total pages : 272
  • ISBN : 0128039604
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Summary : BACE inhibitors and their use in the treatment of Alzheimer's Disease BACE (β-site of APP cleaving enzyme) is a critical component in Alzheimer's Disease (AD), and the development of BACE inhibitors shows great potential as a therapy for the disease. BACE: Lead Target for Orchestrated Therapy of Alzheimer's Disease covers ...

The Neurobiology of Alzheimer s Disease

The Neurobiology of Alzheimer s Disease
  • Author : Suzanne Corkin,Roger M. Nitsch,John Herbert Growdon
  • Publisher : Unknown
  • Release Date : 1996
  • Total pages : 439
  • ISBN : 0128039604
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Summary : The overall goal of the International Study Group on the Pharmacology of Memory Disorders Associated with Ageing is to point out discoveries that shed light on the potential causes of Alzheimer's disease, its pathogenesis, and the biological mechanisms that could underlie its cure. This eighth meeting in the series, aims ...

Chemoinformatics Approaches to Structure and Ligand Based Drug Design

Chemoinformatics Approaches to Structure  and Ligand Based Drug Design
  • Author : Adriano D. Andricopulo,Leonardo L. G. Ferreira
  • Publisher : Frontiers Media SA
  • Release Date : 2019-02-05
  • Total pages : 212
  • ISBN : 0128039604
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Summary : Chemoinformatics is paramount to current drug discovery. Structure- and ligand-based drug design strategies have been used to uncover hidden patterns in large amounts of data, and to disclose the molecular aspects underlying ligand-receptor interactions. This Research Topic aims to share with a broad audience the most recent trends in the ...

Alzheimer s Disease Sourcebook

Alzheimer s Disease Sourcebook
  • Author : Karen Bellenir
  • Publisher : Unknown
  • Release Date : 1999
  • Total pages : 524
  • ISBN : 0128039604
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Summary : It provides information to help patients and their families understand the differences between reversible and irreversible causes of dementia, comprehend the results of current research initiatives, and know what to expect as Alzheimer's disease progresses. A glossary and resource listings provide additional sources of help and information."--BOOK JACKET....

Biomarkers for Early Diagnosis of Alzheimer s Disease

Biomarkers for Early Diagnosis of Alzheimer s Disease
  • Author : Daniela Galimberti,Elio Scarpani
  • Publisher : Nova Science Publishers
  • Release Date : 2008
  • Total pages : 307
  • ISBN : 0128039604
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Summary : Alzheimer's disease (AD) is characterized by the deposition into the brain of amyloid peptide, which originates a cascade of inflammatory events leading eventually to neuronal death. These pathological events likely occur several years before the clinical manifestation of the disease, implying that potential therapeutical interventions are currently started too late ...

Translational Medicine

Translational Medicine
  • Author : Robert A. Meyers
  • Publisher : John Wiley & Sons
  • Release Date : 2018-07-16
  • Total pages : 1064
  • ISBN : 0128039604
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Summary : This reference work gives a compete overview of the different stages of drug development using a translational approach. The book is structured in different parts, following the different stages in drug development. Almost half of the work is dedicated to core of drug discovery using a translational approach, the identification ...

Genetic Engineering Biotechnology News

Genetic Engineering   Biotechnology News
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 212
  • ISBN : 0128039604
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Summary : Download or read online Genetic Engineering Biotechnology News written by , published by which was released on 2009. Get Genetic Engineering Biotechnology News Books now! Available in PDF, ePub and Kindle....

Comparative Genomics and Proteomics in Drug Discovery

Comparative Genomics and Proteomics in Drug Discovery
  • Author : John Parrington,Kevin Coward
  • Publisher : Taylor & Francis
  • Release Date : 2007
  • Total pages : 182
  • ISBN : 0128039604
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Summary : Comparative Genomics and Proteomics in Drug Discovery gives an overview of how emerging genomic and proteomic technologies are making significant contributions to global drug discovery programs, and in particular the key role that comparative genomics and proteomics play within this strategy. Each chapter is written by respected authorities, with hands-on ...

Burger s Medicinal Chemistry and Drug Discovery Therapeutic agents

Burger s Medicinal Chemistry and Drug Discovery  Therapeutic agents
  • Author : Alfred Burger
  • Publisher : Unknown
  • Release Date : 1995
  • Total pages : 8
  • ISBN : 0128039604
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Summary : Download or read online Burger s Medicinal Chemistry and Drug Discovery Therapeutic agents written by Alfred Burger, published by which was released on 1995. Get Burger s Medicinal Chemistry and Drug Discovery Therapeutic agents Books now! Available in PDF, ePub and Kindle....

Drug Discovery and Development

Drug Discovery and Development
  • Author : H. P. Rang,Daniel Vasella
  • Publisher : Churchill Livingstone
  • Release Date : 2006
  • Total pages : 346
  • ISBN : 0128039604
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Summary : 'Drug Discovery and Development' describes the huge complexities involved in bringing a drug to market and how new molecular understanding and techniques can make the process more targeted and successful....