DNA Modifications in the Brain

Written By Timothy W. Bredy
DNA Modifications in the Brain
  • Publsiher : Academic Press
  • Release : 05 January 2017
  • ISBN : 9780128015964
  • Pages : 150 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled DNA Modifications in the Brain written by Timothy W. Bredy which was release on 05 January 2017, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states. Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate and advanced undergraduate students, but is also a great resource for researchers who need a broad introduction to the dynamic nature of DNA that sheds light on evolving concepts of gene-environment interaction and their effects on adaptation and neuropsychiatric disease. Provides a comprehensive overview of the many facets of DNA modifications Discusses the impact of this dynamic epigenetic mechanism across brain development and lifespan at behavioral, cognitive, molecular and genetic levels Contains contributions by influential leaders in the field Edited by a Neuroscientist to further promote synthesis between epigenetics, neuroscience, and clinical relevance

DNA Modifications in the Brain

DNA Modifications in the Brain
  • Author : Timothy W. Bredy
  • Publisher : Academic Press
  • Release Date : 2017-01-05
  • Total pages : 150
  • ISBN : 9780128015964
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Summary : DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and ...

DNA Modifications in the Brain

DNA Modifications in the Brain
  • Author : Timothy W Bredy
  • Publisher : Academic Press
  • Release Date : 2016-12-23
  • Total pages : 180
  • ISBN : 9780128015964
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Summary : DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and ...

Epigenetics Brain and Behavior

Epigenetics  Brain and Behavior
  • Author : Paolo Sassone Corsi,Yves Christen
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-10-19
  • Total pages : 166
  • ISBN : 9780128015964
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Summary : Recent years have seen spectacular advances in the filed of epigenetics. These have attracted the interest of researchers in many fields and evidence connecting epigentic regulation to brain functions has been accumulationg. Neurons daily convert a variety of external stimuli into rapid or long-lasting changes in gene expression. A variety ...

The Epigenetics of Suicide

The Epigenetics of Suicide
  • Author : Benoit Labonté
  • Publisher : Unknown
  • Release Date : 2013
  • Total pages : 212
  • ISBN : 9780128015964
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Summary : "Suicide is a problem resulting from the interaction between several factors. Among these factors, early-life adversity, characterized by child sexual and physical abuse as well as parental neglect, is one of the strongest risk factors for depression and suicidal behaviors. While it is clear that child abuse increases the risk ...

The Effects of Sodium Butyrate NaB and Maltreatment Early in Postnatal Development on DNA Methylation in the Hippocampus and Amygdala of Adult Male Rats

The Effects of Sodium Butyrate  NaB  and Maltreatment Early in Postnatal Development on DNA Methylation in the Hippocampus and Amygdala of Adult Male Rats
  • Author : Isabella Archer
  • Publisher : Unknown
  • Release Date : 2019
  • Total pages : 32
  • ISBN : 9780128015964
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Summary : Early life stress, especially childhood maltreatment, increases the risk for cognitive dysfunction and mental problems later in life. Studies have sought to identify how these phenotypes come about by examining structural and functional changes in various brain regions. Recent work has also focused on identifying whether changes in DNA methylation, ...

Brain Behavior and Epigenetics

Brain  Behavior and Epigenetics
  • Author : Arturas Petronis,Jonathan Mill
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-05-19
  • Total pages : 320
  • ISBN : 9780128015964
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Summary : Biomedical research in the first decade of the 21st century has been marked by a rapidly growing interest in epigenetics. The reasons for this are numerous, but primarily it stems from the mounting realization that research programs focused solely on DNA sequence variation, despite their breadth and depth, are unlikely ...

Patho Epigenetics of Disease

Patho Epigenetics of Disease
  • Author : Janos Minarovits,Hans Helmut Niller
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-06-14
  • Total pages : 466
  • ISBN : 9780128015964
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Summary : In multicellular organisms the establishment, maintenance, and programmed alterations of cell-type specific gene expression patterns are regulated by epigenetic mechanisms. Thus, epigenetic alterations (DNA methylation, DNA associated Polycomb-Trithorax protein complexes, histone modifications) ensure the unique transcriptional activity and phenotypic diversity of diploid cells that carry identical or nearly identical DNA ...

The DNA RNA and Histone Methylomes

The DNA  RNA  and Histone Methylomes
  • Author : Stefan Jurga,Jan Barciszewski
  • Publisher : Springer Nature
  • Release Date : 2019-08-28
  • Total pages : 624
  • ISBN : 9780128015964
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Summary : This book reviews the chemical, regulatory, and physiological mechanisms of protein arginine and lysine methyltransferases, as well as nucleic acid methylations and methylating enzymes. Protein and nucleic acid methylation play key and diverse roles in cellular signalling and regulating macromolecular cell functions. Protein arginine and lysine methyltransferases are the predominant ...

Epigenetics and Neuroplasticity Evidence and Debate

Epigenetics and Neuroplasticity   Evidence and Debate
  • Author : Schahram Akbarian,Farah Lubin
  • Publisher : Academic Press
  • Release Date : 2014-11-12
  • Total pages : 250
  • ISBN : 9780128015964
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Summary : The 'epi-(Greek for 'over', 'above')genome', with its rich cache of highly regulated, structural modifications-including DNA methylation, histone modifications and histone variants-defines the moldings and three-dimensional structures of the genomic material inside the cell nucleus and serves, literally, as a molecular bridge linking the environment to the genetic materials ...

The Neurobiology of Brain and Behavioral Development

The Neurobiology of Brain and Behavioral Development
  • Author : Robbin Gibb,Bryan Kolb
  • Publisher : Academic Press
  • Release Date : 2017-11-02
  • Total pages : 496
  • ISBN : 9780128015964
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Summary : The Neurobiology of Brain and Behavioral Development provides an overview of the process of brain development, including recent discoveries on how the brain develops. This book collates and integrates these findings, weaving the latest information with core information on the neurobiology of brain development. It focuses on cortical development, but ...

Stem Cell Epigenetics

Stem Cell Epigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2020-08-13
  • Total pages : 330
  • ISBN : 9780128015964
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Summary : Stem Cell Epigenetics, Volume 16, examines how epigenetics are involved in stem cell differentiation, how a stem cell rapidly transitions into a molecularly distinct cell type, and how this process may be reversed or managed via epigenetic reprogramming. Topics discussed include chromatin in pluripotency, epigenetic regulation of reprogramming, stem cells and ...

Brain Tumors in the Chemical Industry

Brain Tumors in the Chemical Industry
  • Author : Irving J. Selikoff,Edward Cuyler Hammond
  • Publisher : Unknown
  • Release Date : 1982
  • Total pages : 364
  • ISBN : 9780128015964
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Summary : Download or read online Brain Tumors in the Chemical Industry written by Irving J. Selikoff,Edward Cuyler Hammond, published by which was released on 1982. Get Brain Tumors in the Chemical Industry Books now! Available in PDF, ePub and Kindle....

Sex and the Developing Brain

Sex and the Developing Brain
  • Author : Margaret M. McCarthy
  • Publisher : Biota Publishing
  • Release Date : 2017-08-31
  • Total pages : 141
  • ISBN : 9780128015964
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Summary : The brains of males and females, men and women, are different, that is a fact. What is debated is how different and how important are those differences. Sex differences in the brain are determined by genetics, hormones, and experience, which in humans includes culture, society, and parental and peer expectations. ...

Neurobiology of Brain Tumors

Neurobiology of Brain Tumors
  • Author : Michael Salcman
  • Publisher : Unknown
  • Release Date : 1991
  • Total pages : 386
  • ISBN : 9780128015964
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Summary : Epidemiology & classification/oncogenesis & growth/therapeu- tic rationale & modes of trmt/cell biology of brain tumors....

Neuroepigenomics in Aging and Disease

Neuroepigenomics in Aging and Disease
  • Author : Raul Delgado-Morales
  • Publisher : Springer
  • Release Date : 2017-05-18
  • Total pages : 525
  • ISBN : 9780128015964
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Summary : Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the “physiological epigenome” are increasingly associated with human diseases. During the last decade the emerging field of neuroepigenomics have started to impact tremendously in areas such learning and memory, addiction or neurodegeneration. This ...