Computer Aided Applications in Pharmaceutical Technology

Written By Jelena Djuris
Computer Aided Applications in Pharmaceutical Technology
  • Publsiher : Elsevier
  • Release : 10 April 2013
  • ISBN : 1908818328
  • Pages : 300 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Computer Aided Applications in Pharmaceutical Technology written by Jelena Djuris which was release on 10 April 2013, this book published by Elsevier. Available in PDF, EPUB and Kindle Format. Book excerpt: Research and development in the pharmaceutical industry is a time-consuming and expensive process, making it difficult for newly developed drugs to be formulated into commercially available products. Both formulation and process development can be optimized by means of statistically organized experiments, artificial intelligence and other computational methods. Simultaneous development and investigation of pharmaceutical products and processes enables application of quality by design concept that is being promoted by the regulatory authorities worldwide. Computer-aided applications in pharmaceutical technology covers the fundamentals of experimental design application and interpretation in pharmaceutical technology, chemometric methods with emphasis of their application in process control, neural computing (artificial neural networks, fuzzy logic and decision trees, evolutionary computing and genetic algorithms, self-organizing maps), computer-aided biopharmaceutical characterization as well as application of computational fluid dynamics in pharmaceutical technology. All of these techniques are essential tools for successful building of quality into pharmaceutical products and processes from the early stage of their development to selection of the optimal ones. In addition to theoretical aspects of various methods, the book provides numerous examples of their application in the field of pharmaceutical technology. A comprehensive review of the current state of the art on various computer aided applications in pharmaceutical technology Case studies are presented in order to facilitate understanding of various concepts in computer-aided applications

Computer Aided Applications in Pharmaceutical Technology

Computer Aided Applications in Pharmaceutical Technology
  • Author : Jelena Djuris
  • Publisher : Elsevier
  • Release Date : 2013-04-10
  • Total pages : 300
  • ISBN : 1908818328
GET BOOK

Summary : Research and development in the pharmaceutical industry is a time-consuming and expensive process, making it difficult for newly developed drugs to be formulated into commercially available products. Both formulation and process development can be optimized by means of statistically organized experiments, artificial intelligence and other computational methods. Simultaneous development and ...

Computer aided applications in pharmaceutical technology

Computer aided applications in pharmaceutical technology
  • Author : Sandra Grbic,Jelena Parojcic,Zorica Djuric
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-04-10
  • Total pages : 300
  • ISBN : 1908818328
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Summary : This chapter introduces the concept of gastrointestinal absorption simulation using in silico methodology. Parameters used for model construction and the sensitivity predicted pharmacokinetic responses to various input parameters are described. Virtual trials for in silico modeling of drug absorption are presented. The influence of food on drug absorption, as well ...

Computer aided applications in pharmaceutical technology

Computer aided applications in pharmaceutical technology
  • Author : Ljiljana Djekic,Dragana Vasiljevic,Marija Primorac
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-04-10
  • Total pages : 300
  • ISBN : 1908818328
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Summary : This chapter introduces the concept of formulation development assisted by computer applications. Development and optimization of various types of pharmaceutical emulsions microemulsions, self-microemulsifying systems, and double emulsions are presented. Illustrative examples are presented to demonstrate the ability of computer-aided tools to facilitate formulation development. Various techniques, such as design of ...

Computer aided applications in pharmaceutical technology

Computer aided applications in pharmaceutical technology
  • Author : Jelena Djuris,Svetlana Ibric,Zorica Djuric
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-04-10
  • Total pages : 300
  • ISBN : 1908818328
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Summary : This chapter presents a review of the possible applications of methods based on neural computing in pharmaceutical products and process development. Some of the methods described are used for classification purposes, whereas others can be applied to modeling and optimization, or even induction of rules. Basic concepts of each method ...

Computer aided applications in pharmaceutical technology

Computer aided applications in pharmaceutical technology
  • Author : Jelena Djuris,Svetlana Ibric,Zorica Djuric
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-04-10
  • Total pages : 300
  • ISBN : 1908818328
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Summary : This chapter provides a basic theoretical background on experimental design application and interpretation. Techniques described include screening designs, full and fractional factorial designs, Plackett–Burman design, D-optimal designs, response surface methodology, central composite designs, Box–Behnken design, and mixture designs, etc. The reader will be introduced to the experimental domains ...

Computer aided applications in pharmaceutical technology

Computer aided applications in pharmaceutical technology
  • Author : Ivana Masic,Jelena Parojcic,Zorica Djuric
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-04-10
  • Total pages : 300
  • ISBN : 1908818328
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Summary : This chapter introduces the concept of computational fluid dynamics (CFD) and its applications in pharmaceutical technology. Basic theoretical explanations on the mathematics of fluid flow and numerical grids are provided. CFD is a versatile tool that is mainly used in complex dynamical process characterization. Examples of CFD applications in development ...

Computer Applications in Pharmaceutical Science

Computer Applications in Pharmaceutical Science
  • Author : S. L. Lim
  • Publisher : Unknown
  • Release Date : 2019-09-19
  • Total pages : 212
  • ISBN : 1908818328
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Summary : Research and development in the pharmaceutical industry is a time-consuming and expensive process, making it difficult for newly developed drugs to be formulated into commercially available products. Both formulation and process development can be optimized by means of statistically organized experiments, artificial intelligence and other computational methods. Simultaneous development and ...

Computer Aided Vaccine Design

Computer Aided Vaccine Design
  • Author : Joo Chuan Tong,Shoba Ranganathan
  • Publisher : Elsevier
  • Release Date : 2013-07-31
  • Total pages : 164
  • ISBN : 1908818328
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Summary : Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates. Computer-aided vaccine design is a comprehensive introduction to this exciting field of study. The book is intended to be a textbook for researchers and for courses in bioinformatics, as well as a laboratory reference guide. It ...

An Introduction to Pharmaceutical Sciences

An Introduction to Pharmaceutical Sciences
  • Author : Jiben Roy
  • Publisher : Elsevier
  • Release Date : 2011-07-25
  • Total pages : 446
  • ISBN : 1908818328
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Summary : This textbook is written as a unified approach to various topics, ranging from drug discovery to manufacturing, techniques and technology, regulation and marketing. The key theme of the book is pharmaceuticals - what every student of pharmaceutical sciences should know: from the active pharmaceutical ingredients to the preparation of various ...

Multivariate Analysis in the Pharmaceutical Industry

Multivariate Analysis in the Pharmaceutical Industry
  • Author : Ana Patricia Ferreira,Jose C. Menezes,Mike Tobyn
  • Publisher : Academic Press
  • Release Date : 2018-04-24
  • Total pages : 464
  • ISBN : 1908818328
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Summary : Multivariate Analysis in the Pharmaceutical Industry provides industry practitioners with guidance on multivariate data methods and their applications over the lifecycle of a pharmaceutical product, from process development, to routine manufacturing, focusing on the challenges specific to each step. It includes an overview of regulatory guidance specific to the use ...

Nanoscale Fabrication Optimization Scale up and Biological Aspects of Pharmaceutical Nanotechnology

Nanoscale Fabrication  Optimization  Scale up and Biological Aspects of Pharmaceutical Nanotechnology
  • Author : Alexandru Mihai Grumezescu
  • Publisher : William Andrew
  • Release Date : 2017-12-11
  • Total pages : 696
  • ISBN : 1908818328
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Summary : Nanoscale Fabrication, Optimization, Scale-up and Biological Aspects of Pharmaceutical Nanotechnology focuses on the fabrication, optimization, scale-up and biological aspects of pharmaceutical nanotechnology. In particular, the following aspects of nanoparticle preparation methods are discussed: the need for less toxic reagents, simplification of the procedure to allow economic scale-up, and optimization to ...

Computer Applications in Pharmaceutical Research and Development

Computer Applications in Pharmaceutical Research and Development
  • Author : Sean Ekins
  • Publisher : John Wiley & Sons
  • Release Date : 2006-07-11
  • Total pages : 805
  • ISBN : 1908818328
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Summary : A unique, holistic approach covering all functions and phases of pharmaceutical research and development While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug ...

Sterility Sterilisation and Sterility Assurance for Pharmaceuticals

Sterility  Sterilisation and Sterility Assurance for Pharmaceuticals
  • Author : Tim Sandle
  • Publisher : Elsevier
  • Release Date : 2013-10-31
  • Total pages : 362
  • ISBN : 1908818328
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Summary : Failure to adequately control any microbial challenge associated within process or product by robust sterilisation will result in a contaminated marketed product, with potential harm to the patient. Sterilisation is therefore of great importance to healthcare and the manufacturers of medical devices and pharmaceuticals. Sterility, sterilisation and sterility assurance for ...

Formulation tools for Pharmaceutical Development

Formulation tools for Pharmaceutical Development
  • Author : J E Aguilar
  • Publisher : Elsevier
  • Release Date : 2013-09-30
  • Total pages : 304
  • ISBN : 1908818328
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Summary : A range of new and innovative tools used for preformulation and formulation of medicines help optimize pharmaceutical development projects. Such tools also assist with the performance evaluation of the pharmaceutical process, allowing any potential gaps to be identified. These tools can be applied in both basic research and industrial environment. ...

Bioinformatics for Biomedical Science and Clinical Applications

Bioinformatics for Biomedical Science and Clinical Applications
  • Author : K-H Liang
  • Publisher : Elsevier
  • Release Date : 2013-07-31
  • Total pages : 170
  • ISBN : 1908818328
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Summary : Contemporary biomedical and clinical research is undergoing constant development thanks to the rapid advancement of various high throughput technologies at the DNA, RNA and protein levels. These technologies can generate vast amounts of raw data, making bioinformatics methodologies essential in their use for basic biomedical and clinical applications. Bioinformatics for ...