Computational Non coding RNA Biology

Written By Yun Zheng
Computational Non coding RNA Biology
  • Publsiher : Academic Press
  • Release : 14 September 2018
  • ISBN : 0128143665
  • Pages : 320 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Computational Non coding RNA Biology written by Yun Zheng which was release on 14 September 2018, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Computational Non-coding RNA Biology is a resource for the computation of non-coding RNAs. The book covers computational methods for the identification and quantification of non-coding RNAs, including miRNAs, tasiRNAs, phasiRNAs, lariat originated circRNAs and back-spliced circRNAs, the identification of miRNA/siRNA targets, and the identification of mutations and editing sites in miRNAs. The book introduces basic ideas of computational methods, along with their detailed computational steps, a critical component in the development of high throughput sequencing technologies for identifying different classes of non-coding RNAs and predicting the possible functions of these molecules. Finding, quantifying, and visualizing non-coding RNAs from high throughput sequencing datasets at high volume is complex. Therefore, it is usually possible for biologists to complete all of the necessary steps for analysis. Presents a comprehensive resource of computational methods for the identification and quantification of non-coding RNAs Introduces 23 practical computational pipelines for various topics of non-coding RNAs Provides a guide to assist biologists and other researchers dealing with complex datasets Introduces basic computational methods and provides guidelines for their replication by researchers Offers a solution to researchers approaching large and complex sequencing datasets

Computational Non coding RNA Biology

Computational Non coding RNA Biology
  • Author : Yun Zheng
  • Publisher : Academic Press
  • Release Date : 2018-09-14
  • Total pages : 320
  • ISBN : 0128143665
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Summary : Computational Non-coding RNA Biology is a resource for the computation of non-coding RNAs. The book covers computational methods for the identification and quantification of non-coding RNAs, including miRNAs, tasiRNAs, phasiRNAs, lariat originated circRNAs and back-spliced circRNAs, the identification of miRNA/siRNA targets, and the identification of mutations and editing sites ...

Computational Biology of Non Coding RNA

Computational Biology of Non Coding RNA
  • Author : Xin Lai,Shailendra K. Gupta,Julio Vera
  • Publisher : Humana Press
  • Release Date : 2019-02-04
  • Total pages : 390
  • ISBN : 0128143665
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Summary : This volume details a collection of state-of-art methods including identification of novel ncRNAs and their targets, functional annotation and disease association in different biological contexts. Chapters guide readers through an overview of disease-specific ncRNAs, computational methods and workflows for ncRNA discovery, annotation based on high-throughput sequencing data, bioinformatics tools and ...

Computational Identification and Analysis of Non coding RNAs in Large scale Biological Data

Computational Identification and Analysis of Non coding RNAs in Large scale Biological Data
  • Author : Jikai Lei
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 118
  • ISBN : 0128143665
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Summary : Download or read online Computational Identification and Analysis of Non coding RNAs in Large scale Biological Data written by Jikai Lei, published by which was released on 2015. Get Computational Identification and Analysis of Non coding RNAs in Large scale Biological Data Books now! Available in PDF, ePub and Kindle....

Long Non Coding Rnas Methods and Protocols

Long Non Coding Rnas  Methods and Protocols
  • Author : Yi Feng,Lin Zhang
  • Publisher : Methods in Molecular Biology
  • Release Date : 2018-04-15
  • Total pages : 312
  • ISBN : 0128143665
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Summary : This volume assembles a broad spectrum of methods used in long non-coding RNAs (lncRNA) research, ranging from computational annotation of lncRNA genes to molecular and cellular analyses of the function of individual lncRNA. Long Non-Coding RNAs: Methods and Protocols also discusses methods used to study circular RNAs and RNA splicing, ...

Molecular Biology of Long Non coding RNAs

Molecular Biology of Long Non coding RNAs
  • Author : Ahmad M. Khalil,Jeff Coller
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-09-20
  • Total pages : 227
  • ISBN : 0128143665
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Summary : ​Long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. ​So, while their function is not entirely clear, they may serve as ...

The Chemical Biology of Long Noncoding RNAs

The Chemical Biology of Long Noncoding RNAs
  • Author : Stefan Jurga,Jan Barciszewski
  • Publisher : Springer Nature
  • Release Date : 2020-10-01
  • Total pages : 545
  • ISBN : 0128143665
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Summary : This book offers a comprehensive and detailed overview of various aspects of long non-coding RNAs. It discusses their emerging significance in molecular medicine, ranging from human cancers to cardiovascular and metabolic diseases. Transcriptomic studies have demonstrated that the majority of genomes found in complex organisms are expressed in highly dynamic ...

RNA Based Regulation in Human Health and Disease

RNA Based Regulation in Human Health and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2020-08-15
  • Total pages : 444
  • ISBN : 0128143665
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Summary : RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and ...

Computational Biology and Bioinformatics

Computational Biology and Bioinformatics
  • Author : Ka-Chun Wong
  • Publisher : CRC Press
  • Release Date : 2016-04-27
  • Total pages : 425
  • ISBN : 0128143665
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Summary : The advances in biotechnology such as the next generation sequencing technologies are occurring at breathtaking speed. Advances and breakthroughs give competitive advantages to those who are prepared. However, the driving force behind the positive competition is not only limited to the technological advancement, but also to the companion data analytical ...

Advances in Bioinformatics and Computational Biology

Advances in Bioinformatics and Computational Biology
  • Author : Ronnie Alves
  • Publisher : Springer
  • Release Date : 2018-10-23
  • Total pages : 147
  • ISBN : 0128143665
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Summary : This book constitutes the refereed proceedings of the 11th Brazilian Symposium on Bioinformatics, BSB 2018, held in Rio de Janeiro, Brazil, in October/November 2018. The 13 revised full papers presented were carefully reviewed and selected from 26 submissions. The papers cover all aspects of bioinformatics and computational biology....

Identification and Classification of Long Non Coding RNA in Zea Mays Using Computational and Bioinformatic Approaches

Identification and Classification of Long Non Coding RNA in Zea Mays Using Computational and Bioinformatic Approaches
  • Author : Susan Boerner
  • Publisher : Unknown
  • Release Date : 2012
  • Total pages : 212
  • ISBN : 0128143665
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Summary : ABSTRACT: Computational analysis of cDNA sequences from multiple organisms suggests that a large portion of transcribed DNA does not code for a functional protein. As studies begin to delve into the possible functions of these noncoding transcripts, the results are revealing an ever more complex genome, where what was once ...

Cancer and Noncoding RNAs

Cancer and Noncoding RNAs
  • Author : Jayprokas Chakrabarti,Sanga Mitra
  • Publisher : Academic Press
  • Release Date : 2017-10-13
  • Total pages : 576
  • ISBN : 0128143665
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Summary : Cancer and Noncoding RNAs offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and ...

Bioinformatics of Non Coding RNAs with Applications to Biomedicine Recent Advances and Open Challenges

Bioinformatics of Non Coding RNAs with Applications to Biomedicine  Recent Advances and Open Challenges
  • Author : Carlo Maria Croce,Alfredo Ferro,Alessandro Laganà
  • Publisher : Frontiers Media SA
  • Release Date : 2017-01-27
  • Total pages : 212
  • ISBN : 0128143665
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Summary : The recent discovery of small and long non-coding RNAs (ncRNAs) has represented a major breakthrough in the life sciences. These molecules add a new layer of complexity to biological processes and pathways by revealing a sophisticated and dynamic interconnected system whose structure is just beginning to be uncovered. Genetic and ...

Long Noncoding RNA Interactions in Cancer

Long Noncoding RNA Interactions in Cancer
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2017
  • Total pages : 444
  • ISBN : 0128143665
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Summary : Download or read online Long Noncoding RNA Interactions in Cancer written by , published by which was released on 2017. Get Long Noncoding RNA Interactions in Cancer Books now! Available in PDF, ePub and Kindle....

Regulatory RNAs

Regulatory RNAs
  • Author : Bibekanand Mallick,Zhumur Ghosh
  • Publisher : Springer
  • Release Date : 2014-04-13
  • Total pages : 554
  • ISBN : 0128143665
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Summary : Recent progress in high-throughput technologies and genome wide transcriptome studies have lead to a significant scientific milestone of discovering non-coding RNAs (ncRNAs) which spans through a major portion of the genome. These RNAs most often act as riboregulators, and actively participate in the regulation of important cellular functions at the ...

Computational Methods for Genome wide Non coding RNA Discovery and Analysis

Computational Methods for Genome wide Non coding RNA Discovery and Analysis
  • Author : Shaojie Zhang
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 108
  • ISBN : 0128143665
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Summary : The discovery of novel non-coding RNAs has been among the most exciting recent developments in Biology, yet, many more remain undiscovered. It has been hypothesized that there is in fact an abundance of functional non-coding RNAs (ncRNAs) with various catalytic and regulatory functions. Computational methods tailored specifically for ncRNA discovery ...