Chemical Sciences in Early Drug Discovery

Written By Pierfausto Seneci
Chemical Sciences in Early Drug Discovery
  • Publsiher : Elsevier
  • Release : 05 June 2018
  • ISBN : 008099928X
  • Pages : 194 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Chemical Sciences in Early Drug Discovery written by Pierfausto Seneci which was release on 05 June 2018, this book published by Elsevier. Available in PDF, EPUB and Kindle Format. Book excerpt: Chemical Sciences in Early Drug Discovery: Medicinal Chemistry 2.0 describes how new technologies and approaches can be used to improve the probability of success in fulfilling the perennial goal of finding and developing new drugs. Drawing on the author's extensive experience consulting and teaching in medicinal chemistry, the book outlines ways in which medicinal chemistry is widening its reach to meet modern demands, and how modern technologies and approaches are facilitating this growth into new fields. Supported by examples throughout, the book is a practical resource for organic-medicinal chemists, biological chemists and pharmacologists involved in drug discovery. Reviews the key application of chemistry in drug discovery for both medicinal and non-medicinal chemists, clarifying and explaining the role of medicinal chemistry in supporting the modern drug discovery pipeline Shows how a wider medicinal chemistry view is essential for anyone in an integrated drug discovery project looking to reduce costs and save time Provides the critical success factors needed to successfully identify hits from both biological and chemical perspectives

Chemical Sciences in Early Drug Discovery

Chemical Sciences in Early Drug Discovery
  • Author : Pierfausto Seneci
  • Publisher : Elsevier
  • Release Date : 2018-06-05
  • Total pages : 194
  • ISBN : 008099928X
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Summary : Chemical Sciences in Early Drug Discovery: Medicinal Chemistry 2.0 describes how new technologies and approaches can be used to improve the probability of success in fulfilling the perennial goal of finding and developing new drugs. Drawing on the author's extensive experience consulting and teaching in medicinal chemistry, the book outlines ways ...

Small Molecule Drug Discovery

Small Molecule Drug Discovery
  • Author : Andrea Trabocchi,Elena Lenci
  • Publisher : Elsevier
  • Release Date : 2019-11-23
  • Total pages : 356
  • ISBN : 008099928X
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Summary : Small Molecule Drug Discovery: Methods, Molecules and Applications presents the methods used to identify bioactive small molecules, synthetic strategies and techniques to produce novel chemical entities and small molecule libraries, chemoinformatics to characterize and enumerate chemical libraries, and screening methods, including biophysical techniques, virtual screening and phenotypic screening. The second ...

Pharmaceutical Process Development

Pharmaceutical Process Development
  • Author : John Blacker,Michael T Williams
  • Publisher : Royal Society of Chemistry
  • Release Date : 2011-08-17
  • Total pages : 374
  • ISBN : 008099928X
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Summary : Pharmaceutical process research and development is an exacting, multidisciplinary effort but a somewhat neglected discipline in the chemical curriculum. This book presents an overview of the many facets of process development and how recent advances in synthetic organic chemistry, process technology and chemical engineering have impacted on the manufacture of ...

High Throughput Analysis for Early Drug Discovery

High Throughput Analysis for Early Drug Discovery
  • Author : James Kyranos
  • Publisher : Elsevier
  • Release Date : 2004-09-18
  • Total pages : 204
  • ISBN : 008099928X
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Summary : High Throughput Analysis for Early Drug Discovery offers concise and unbiased presentations by synthetic and analytical chemists who have been involved in creating and moving the field of combinatorial chemistry into the academic and industrial mainstream. Since the synthetic method often dictates the appropriate types of analysis, each chapter or ...

Lead Generation Approaches in Drug Discovery

Lead Generation Approaches in Drug Discovery
  • Author : Zoran Rankovic,Richard Morphy
  • Publisher : John Wiley & Sons
  • Release Date : 2010-04-07
  • Total pages : 308
  • ISBN : 008099928X
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Summary : An integrated overview of modern approaches to lead discovery Lead generation is increasingly seen as a distinct and success-determining phase of the drug discovery process. Over recent years, there have been major advances in the understanding of what constitutes a good lead compound and how to improve the chances of ...

Exploiting Chemical Diversity for Drug Discovery

Exploiting Chemical Diversity for Drug Discovery
  • Author : Paul Allan Bartlett,Michael Entzeroth
  • Publisher : RSC Biomolecular Sciences (unn
  • Release Date : 2006
  • Total pages : 420
  • ISBN : 008099928X
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Summary : This book examines the many aspects of the drug discovery process and presents the current state-of-the-art and a clear overview of approaches to lead identification....

Managing the Drug Discovery Process

Managing the Drug Discovery Process
  • Author : Walter Moos,Susan Miller,Stephen Munk,Barbara Munk
  • Publisher : Woodhead Publishing
  • Release Date : 2016-11-08
  • Total pages : 536
  • ISBN : 008099928X
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Summary : Managing the Drug Discovery Process: How to Make It More Efficient and Cost-Effective thoroughly examines the current state of pharmaceutical research and development by providing chemistry-based perspectives on biomedical research, drug hunting and innovation. The book also considers the interplay of stakeholders, consumers, and the drug firm with attendant factors, ...

Early Drug Development 2 Volume Set

Early Drug Development  2 Volume Set
  • Author : Fabrizio Giordanetto
  • Publisher : John Wiley & Sons
  • Release Date : 2018-12-10
  • Total pages : 816
  • ISBN : 008099928X
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Summary : This one-stop reference systematically covers key aspects in early drug development that are directly relevant to the discovery phase and are required for first-in-human studies. Its broad scope brings together critical knowledge from many disciplines, ranging from process technology to pharmacology to intellectual property issues. After introducing the overall early ...

Drug Discovery and Development E Book

Drug Discovery and Development   E Book
  • Author : Raymond G Hill
  • Publisher : Elsevier Health Sciences
  • Release Date : 2012-07-20
  • Total pages : 368
  • ISBN : 008099928X
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Summary : The modern pharmacopeia has enormous power to alleviate disease, and owes its existence almost entirely to the work of the pharmaceutical industry. This book provides an introduction to the way the industry goes about the discovery and development of new drugs. The first part gives a brief historical account from ...

Chemogenomics in Drug Discovery

Chemogenomics in Drug Discovery
  • Author : Hugo Kubinyi,Gerhard Müller
  • Publisher : John Wiley & Sons
  • Release Date : 2006-03-06
  • Total pages : 487
  • ISBN : 008099928X
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Summary : Chemogenomics brings together the most powerful concepts in modern chemistry and biology, linking combinatorial chemistry with genomics and proteomics. This first reference devoted to the topic covers all stages of the early drug discovery process, from target selection to compound library and lead design. With the combined expertise of 20 research ...

Medicinal Chemistry

Medicinal Chemistry
  • Author : Erin Johnson
  • Publisher : Scientific e-Resources
  • Release Date : 2019-06-25
  • Total pages : 316
  • ISBN : 008099928X
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Summary : Medicinal chemistry is the chemistry discipline concerned with the design, development and synthesis of pharmaceutical drugs. The discipline combines expertise from chemistry and pharmacology to identify, develop and synthesize chemical agents that have a therapeutic use and to evaluate the properties of existing drugs. Medicinal Chemistry is a comprehensive and ...

Chronicles of Drug Discovery

Chronicles of Drug Discovery
  • Author : Daniel Lednicer
  • Publisher : Amer Chemical Society
  • Release Date : 1993
  • Total pages : 425
  • ISBN : 008099928X
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Summary : Offers a unique insight into the drug discovery process through informal histories presented by the drugs' inventor. A compilation of accounts describing the events leading from the initial discovery to successful introduction on the market of fourteen important new drugs, including RU 486 (mifepristone) and taxol. Many chapters outline in detail ...

A Guide to the Chemical Basis of Drug Design

A Guide to the Chemical Basis of Drug Design
  • Author : Alfred Burger
  • Publisher : John Wiley & Sons Incorporated
  • Release Date : 1983-09-23
  • Total pages : 300
  • ISBN : 008099928X
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Summary : This book by a leading author in the field of medicinal chemistry deals with the chemical structure of biologically active compounds. Presents a unique historical overview of drug discovery and design using the historical facts of the pharmacology to reveal the serendipity of discovery and to point toward new structures ...

New Drug Discovery and Development

New Drug Discovery and Development
  • Author : Daniel Lednicer
  • Publisher : John Wiley & Sons
  • Release Date : 2006-10-20
  • Total pages : 240
  • ISBN : 008099928X
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Summary : A case history approach to drug synthesis and discovery Discover the origins of some of today’s most popular drug therapies. Explore case histories and gain insight into major classes of antibiotics, antiviral drugs, analgesics, steroids, compounds designed to lower cholesterol, and more. Review the steps required for FDA approval. ...

Magnetic Resonance

Magnetic Resonance
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1999
  • Total pages : 161
  • ISBN : 008099928X
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Summary : Download or read online Magnetic Resonance written by , published by which was released on 1999. Get Magnetic Resonance Books now! Available in PDF, ePub and Kindle....