Breaking Tolerance to Unresponsiveness to Immunotherapy by Natural Killer Cells

Written By Sandro Matosevic
Breaking Tolerance to Unresponsiveness to Immunotherapy by Natural Killer Cells
  • Publsiher : Academic Press
  • Release : 29 January 2021
  • ISBN : 9780128206270
  • Pages : 200 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Breaking Tolerance to Unresponsiveness to Immunotherapy by Natural Killer Cells written by Sandro Matosevic which was release on 29 January 2021, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Breaking Tolerance to Unresponsiveness to Immunotherapy by Natural Killer Cells presents chapters by leaders in translational natural killer cell research and bridges the gap between clinical need and basic science by presenting state-of-the-art knowledge on innate immunity and the challenges associated with translating it to practical adoptive immunotherapies. New approaches, such as the genetic engineering of NK cells and their combination with checkpoint blockade therapies are discussed among other potential interventions to improve natural killer cell functionality against targets. In addition, challenges, such as the difficulty in genetically modifying NK cells or a poor understanding of their effect on checkpoint inhibition are included. The book is a key reference and go-to resource for researchers and clinicians who want to understand the current limitations associated with bringing natural killer cell-based immunotherapies to the clinic. Discusses translational aspects from leaders in the field to facilitate readers' understanding of clinical challenges Addresses important events that occur in patient tumor microenvironments as they pertain to NK cells and how they are, or can be, tackled to overcome immunosuppression of NK cells Focuses on immunometabolism by discussing the metabolic reprogramming that NK cells undergo in solid tumors, including hypoxia, adenosine and other metabolites

Breaking Tolerance to Unresponsiveness to Immunotherapy by Natural Killer Cells

Breaking Tolerance to Unresponsiveness to Immunotherapy by Natural Killer Cells
  • Author : Sandro Matosevic
  • Publisher : Academic Press
  • Release Date : 2021-01-29
  • Total pages : 200
  • ISBN : 9780128206270
GET BOOK

Summary : Breaking Tolerance to Unresponsiveness to Immunotherapy by Natural Killer Cells presents chapters by leaders in translational natural killer cell research and bridges the gap between clinical need and basic science by presenting state-of-the-art knowledge on innate immunity and the challenges associated with translating it to practical adoptive immunotherapies. New approaches, ...

Immunotherapy in Resistant Cancer From the Lab Bench Work to Its Clinical Perspectives

Immunotherapy in Resistant Cancer  From the Lab Bench Work to Its Clinical Perspectives
  • Author : Jorge Morales-Montor,Mariana Segovia-Mendoza
  • Publisher : Academic Press
  • Release Date : 2020-10-14
  • Total pages : 286
  • ISBN : 9780128206270
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Summary : Immunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives provides high level knowledge on detailed mechanisms of actions and biological interactions of different immune drugs, with an aim of offering researchers and clinicians cutting-edge therapies to overcome drug resistance. The book explains the latest immunotherapies for ...

Improving the Therapeutic Ratio in Head and Neck Cancer

Improving the Therapeutic Ratio in Head and Neck Cancer
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-10-04
  • Total pages : 376
  • ISBN : 9780128206270
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Summary : Improving the Therapeutic Ratio in Head and Neck Cancer provides a complete review of current approaches to modulating therapeutic sensitivity in head and neck cancer. It presents a broad background of current approaches and by highlighting the potential for clinical translational, introduces a roadmap for how to move promising preclinical ...

Chemical Abstracts

Chemical Abstracts
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2002
  • Total pages : 212
  • ISBN : 9780128206270
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Summary : Download or read online Chemical Abstracts written by , published by which was released on 2002. Get Chemical Abstracts Books now! Available in PDF, ePub and Kindle....

Renal Cell Carcinoma

Renal Cell Carcinoma
  • Author : Eric A. Klein
  • Publisher : CRC Press
  • Release Date : 1993-04-23
  • Total pages : 368
  • ISBN : 9780128206270
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Summary : This reference brings together all aspects of renal cell carcinoma, and provides a basis for understanding the disease's origin, progression and responses to immunotherapy.;Examining the current status of cytokine, cell-based and chemotherapeutic methods of treatment, this book: discusses the clinical presentation of advanced renal carcinoma and its therapeutic challenges; ...

Cumulated Index Medicus

Cumulated Index Medicus
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1991
  • Total pages : 212
  • ISBN : 9780128206270
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Summary : Download or read online Cumulated Index Medicus written by , published by which was released on 1991. Get Cumulated Index Medicus Books now! Available in PDF, ePub and Kindle....

Cancer Immunotherapy at the Crossroads

Cancer Immunotherapy at the Crossroads
  • Author : James H. Finke,Ronald M. Bukowski
  • Publisher : Springer Science & Business Media
  • Release Date : 2003-11-24
  • Total pages : 386
  • ISBN : 9780128206270
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Summary : Leading investigators and clinicians detail the different mechanisms used by tumors to escape and impair the immune system and then spell out possible clinical strategies to prevent or reverse tumor-induced immune dysfunction. The authors review the mechanisms of immune dysfunction and evasion mechanisms in histologically diverse human tumors, focusing on ...

The Journal of Immunology

The Journal of Immunology
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2005
  • Total pages : 212
  • ISBN : 9780128206270
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Summary : Download or read online The Journal of Immunology written by , published by which was released on 2005. Get The Journal of Immunology Books now! Available in PDF, ePub and Kindle....

Issues in Biological and Life Sciences Research 2011 Edition

Issues in Biological and Life Sciences Research  2011 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2012-01-09
  • Total pages : 5106
  • ISBN : 9780128206270
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Summary : Issues in Biological and Life Sciences Research: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biological and Life Sciences Research. The editors have built Issues in Biological and Life Sciences Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ...