Biomarkers of Alzheimer s Disease The Present and the Future

Written By Sylvain Lehmann
Biomarkers of Alzheimer s Disease  The Present and the Future
  • Publsiher : Frontiers Media SA
  • Release : 10 November 2016
  • ISBN : 2889450414
  • Pages : 212 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Biomarkers of Alzheimer s Disease The Present and the Future written by Sylvain Lehmann which was release on 10 November 2016, this book published by Frontiers Media SA. Available in PDF, EPUB and Kindle Format. Book excerpt: Alzheimer disease (AD) is a neurodegenerative disorder characterized by significant cognitive deficits, behavioral changes, sleep disorders and loss of functional autonomy. AD represents the main cause of dementia and has become a major public health issue. In addition, the number of patients suffering from AD is growing rapidly as the population ages worldwide. Memory impairment is usually the earliest clinical and core symptom of this disease. The diagnosis at a late clinical stage is relatively easy. However, a delay in the diagnosis is damageable for the handling of patients in terms of optimal medical and social care. The actual interest of the scientific head-ways is to optimize the diagnosis in prodromal stage of the disease and to propose personalized therapeutic solutions to individual patients. New revised AD diagnostic criteria include early alteration of cerebrospinal fluid (CSF) biomarkers: decrease of amyloïd peptides (Aβ42), and increase in tau and phosphorylated-tau (p-tau) protein concentration. This recognition of CSF biological biomarkers for the diagnosis of AD is a major step towards the “molecular” diagnosis and follow-up of the disease. Many issues are however still subject of debate. This e-book provides a comprehensive overview of the state of the art of fluid biomarkers for AD, e.g. which novel biomarkers should be implemented in clinical practice for diagnosis or for monitoring treatment or side effects, which ones are new for AD or related dementias or what is the potential of peripheral blood markers. Moreover, the e-Book provides practical guidelines how to optimally and efficiently develop and validate novel biomarker assays, and to document and control pre-analytical variation.

Biomarkers of Alzheimer s Disease The Present and the Future

Biomarkers of Alzheimer s Disease  The Present and the Future
  • Author : Sylvain Lehmann,Charlotte Elisabeth Teunissen
  • Publisher : Frontiers Media SA
  • Release Date : 2016-11-10
  • Total pages : 212
  • ISBN : 2889450414
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Summary : Alzheimer disease (AD) is a neurodegenerative disorder characterized by significant cognitive deficits, behavioral changes, sleep disorders and loss of functional autonomy. AD represents the main cause of dementia and has become a major public health issue. In addition, the number of patients suffering from AD is growing rapidly as the ...

Biomarkers in Alzheimer s Disease

Biomarkers in Alzheimer s Disease
  • Author : Tapan Khan
  • Publisher : Academic Press
  • Release Date : 2016-08-02
  • Total pages : 276
  • ISBN : 2889450414
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Summary : Biomarkers in Alzheimer’s Disease provides a comprehensive overview of all modalities of Alzheimer’s disease biomarkers, including neuroimaging, cerebrospinal fluid, genomic, and peripheral systems. Each chapter integrates molecular/cellular abnormality due to Alzheimer’s disease and technological advancement of biomarkers techniques. The book is ideal for clinical neuroscience and ...

Neuroimaging biomarkers in Alzheimer s disease

Neuroimaging biomarkers in Alzheimer   s disease
  • Author : Samuel Barrack
  • Publisher : iMedPub
  • Release Date : 2013-10
  • Total pages : 136
  • ISBN : 2889450414
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Summary : In view of the growing prevalence of AD worldwide, there is an urgent need for the development of better diagnostic tools and more effective therapeutic interventions. Indeed, much work in this field has been done during last decades. As such, a major goal of current clinical research in AD is ...

Biological Markers of Alzheimer s Disease

Biological Markers of Alzheimer   s Disease
  • Author : Francois Boller,Robert Katzman,Andre Rascol,Jean-Louis Signoret
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-03-08
  • Total pages : 169
  • ISBN : 2889450414
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Summary : This volume presents the proceedings of the symposium held in Toulouse on April 24, 1989, on the topic "Biological Markers of Alzheimer's Disease. " This sym posium was the fourth of a continuing and successful series of Colloques Medecine et Recherche organized by the Fondation IPSEN pour la Recherche Therapeutique, addressing various aspects ...

The Road Less Traveled

The Road Less Traveled
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2014
  • Total pages : 212
  • ISBN : 2889450414
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Summary : Download or read online The Road Less Traveled written by , published by which was released on 2014. Get The Road Less Traveled Books now! Available in PDF, ePub and Kindle....

Atlas of Biomarkers for Alzheimer s Disease

Atlas of Biomarkers for Alzheimer s Disease
  • Author : Manuel Menéndez González
  • Publisher : Springer
  • Release Date : 2014-07-07
  • Total pages : 37
  • ISBN : 2889450414
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Summary : A lot of research on biomarkers for Alzheimer is being done in the last few decades. The aim of these studies is to find some method to ease the diagnosis of Alzheimers as early as possible. Such methods are a range of blood or CSF tests on one hand and ...

Neurodegenerative Diseases

Neurodegenerative Diseases
  • Author : Daniela Galimberti,Elio Scarpini
  • Publisher : Springer Science & Business
  • Release Date : 2014-04-23
  • Total pages : 253
  • ISBN : 2889450414
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Summary : This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer’s disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases. Different aspects of each disease are reviewed, including clinical issues, treatments, basic discoveries (genetics and molecular biology), and translation of basic ...

Biomarkers for Early Diagnosis of Alzheimer s Disease

Biomarkers for Early Diagnosis of Alzheimer s Disease
  • Author : Daniela Galimberti,Elio Scarpani
  • Publisher : Nova Science Publishers
  • Release Date : 2008
  • Total pages : 307
  • ISBN : 2889450414
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Summary : Alzheimer's disease (AD) is characterized by the deposition into the brain of amyloid peptide, which originates a cascade of inflammatory events leading eventually to neuronal death. These pathological events likely occur several years before the clinical manifestation of the disease, implying that potential therapeutical interventions are currently started too late ...

Plasma Biomarkers in Alzheimer s Disease

Plasma Biomarkers in Alzheimer s Disease
  • Author : Hitoshi Sohma
  • Publisher : Unknown
  • Release Date : 2016
  • Total pages : 212
  • ISBN : 2889450414
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Summary : Download or read online Plasma Biomarkers in Alzheimer s Disease written by Hitoshi Sohma, published by which was released on 2016. Get Plasma Biomarkers in Alzheimer s Disease Books now! Available in PDF, ePub and Kindle....

Biochemical biomarkers in Alzheimer s disease

Biochemical biomarkers in Alzheimer   s disease
  • Author : Samuel Barrack
  • Publisher : iMedPub
  • Release Date : 2013-10-20
  • Total pages : 148
  • ISBN : 2889450414
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Summary : In view of the growing prevalence of AD worldwide, there is an urgent need for the development of better diagnostic tools and more effective therapeutic interventions. Indeed, much work in this field has been done during last decades. As such, a major goal of current clinical research in AD is ...

Alzheimer s Disease

Alzheimer s Disease
  • Author : Harald Hampel,Maria C. Carrillo
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2012
  • Total pages : 193
  • ISBN : 2889450414
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Summary : How current biomarkers are modernizing the diagnosis of Alzheimer's disease Expanding knowledge on genetic and epigenetic risk factors is rapidly enhancing our understanding of the complex molecular interactions and systems involved in the pathogenesis of Alzheimer's disease. In this publication, leading experts discuss emerging novel conceptual models of the disease ...

03 POTENTIAL PERIPHERAL BIOMARKERS IN ALZHEIMER S DISEASE PATIENTS DIFFERENCES BETWEEN LEUKOCYTE AND PLATELET PROTEIN EXPRESSION

03   POTENTIAL PERIPHERAL BIOMARKERS IN ALZHEIMER S DISEASE PATIENTS  DIFFERENCES BETWEEN LEUKOCYTE AND PLATELET PROTEIN EXPRESSION
  • Author : Tamires Alves Sarno
  • Publisher : Unknown
  • Release Date : 2017
  • Total pages : 212
  • ISBN : 2889450414
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Summary : Background: The clinical diagnosis of Alzheimeru2019s disease (AD) is a probabilistic formulation that may lack accuracy particularly at early stages of the dementing process. Abnormalities in amyloid-beta precursor protein (APP) metabolism and in the level of APP-secretases have been demonstrated in platelets, and to a lesser extent in leukocytes, ...

Alzheimer s Disease

Alzheimer s Disease
  • Author : Ahmed A. Moustafa
  • Publisher : Academic Press
  • Release Date : 2021-09-01
  • Total pages : 400
  • ISBN : 2889450414
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Summary : Nearly 44 million people have Alzheimer’s or a related dementia worldwide, according to the Alzheimer’s Disease International organization. That number is expected to double every 20 years. Unlike other books on the market, Recent Advancement in Alzheimer’s Disease Research: Neural and Cognitive Studies aims to cover all recent advancements ...

Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders

Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders
  • Author : Paul C. Guest
  • Publisher : Springer
  • Release Date : 2019-02-12
  • Total pages : 328
  • ISBN : 2889450414
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Summary : This book includes a series of reviews on general aspects of biomarker use in the study of psychiatric and neurodegenerative diseases and the development of medications involved in their treatment. It describes the pros and cons of the various approaches and covers the successes and failures in this research field. ...

Identification of Earlier Biomarkers for Alzheimer s Disease

Identification of Earlier Biomarkers for Alzheimer s Disease
  • Author : Ashleigh Parker
  • Publisher : Unknown
  • Release Date : 2019
  • Total pages : 212
  • ISBN : 2889450414
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Summary : Background: Given that individuals with subjective cognitive decline (SCD) report a change that is not yet measurable with standard neuropsychological assessment measures, they are thought to be the earliest along the cognitive continuum between healthy aging and Alzheimer's disease (AD). The current study used a neuroimaging approach to examine differences ...