Antimicrobial Peptides in Gastrointestinal Diseases

Written By Chi Hin Cho
Antimicrobial Peptides in Gastrointestinal Diseases
  • Publsiher : Academic Press
  • Release : 06 June 2018
  • ISBN : 0128143207
  • Pages : 186 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Antimicrobial Peptides in Gastrointestinal Diseases written by Chi Hin Cho which was release on 06 June 2018, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract. The book provides coverage from the basic research to clinical application for GI diseases. Current research and development of AMPs is presented, opening the way for further work on these peptides, not only in the context of GI diseases, but also for similar pathologies in other organs. AMPs are key to the regulation of human microbiome and second line defence in the GI mucosa, prevent colonization of pathogens and modulation of innate response to invading pathogens, and modify immunological reactions during inflammatory processes and oncogenic development in the GI mucosa. More importantly, AMPs possess diversified anti-microbial actions against various infectious diseases in the GI tract. With these physiological functions and pharmacological actions, AMPs have significant potential as therapeutic agents for the treatment of inflammation, cancer and further infection in the GI tract. Provides an overview of AMPs, particularly cathelicidin and defensin, in different diseases Covers inflammation and ulcer repair in the stomach and colon and carcinogenesis in the GI tract Presents AMP information and knowledge in a concise manner Gives useful information on all aspects of AMPs Promotes research on AMPs and their development as drugs, from bench, to clinical application

Antimicrobial Peptides in Gastrointestinal Diseases

Antimicrobial Peptides in Gastrointestinal Diseases
  • Author : Chi Hin Cho
  • Publisher : Academic Press
  • Release Date : 2018-06-06
  • Total pages : 186
  • ISBN : 0128143207
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Summary : Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract. The book provides ...

Antimicrobial Peptides

Antimicrobial Peptides
  • Author : Jürgen Harder,Jens-M. Schröder
  • Publisher : Springer
  • Release Date : 2015-12-24
  • Total pages : 158
  • ISBN : 0128143207
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Summary : This book focuses on the importance of human antimicrobial peptides (AMP) in keeping the host healthy and preventing infectious diseases. The first chapters deal with several examples of the role of AMP in different epithelial organs (skin and wound healing, eye, lung, genito-urinary tract, gut), which are exposed to different ...

Antimicrobial Peptides and Innate Immunity

Antimicrobial Peptides and Innate Immunity
  • Author : Pieter S. Hiemstra,Sebastian A. J. Zaat
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-02-01
  • Total pages : 384
  • ISBN : 0128143207
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Summary : Antimicrobial peptides have been the subject of intense research in the past decades, and are now considered as an essential part of the defense system in bacteria, plants, animals and humans. his book provides an update on these effector molecules of the innate immune system both for researchers who are ...

Antimicrobial Peptides

Antimicrobial Peptides
  • Author : Myung-Dae Seong,Young-Il Hak
  • Publisher : Nova Biomedical
  • Release Date : 2013-01-01
  • Total pages : 168
  • ISBN : 0128143207
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Summary : Antimicrobial peptides (AMPs) are small peptides which exhibit broad-spectrum antimicrobial activity and often activity against virus. In addition, AMPs exert several functions including endotoxin neutralization, chemotactic and immunomodulating activities, angiogenesis, and wound repair. In this book, the authors discuss the innate immune system and lipopolysaccharides; the biological role of fish ...

Antimicrobial Cationic Peptides Advances in Research and Application 2012 Edition

Antimicrobial Cationic Peptides   Advances in Research and Application  2012 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2012-12-26
  • Total pages : 114
  • ISBN : 0128143207
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Summary : Antimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Antimicrobial Cationic Peptides. The editors have built Antimicrobial Cationic Peptides—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ...

Recombinant Production of Growth Factors and Antimicrobial Peptides Using Microorganisms to Modulate Tissue Damage Healing

Recombinant Production of Growth Factors and Antimicrobial Peptides Using Microorganisms to Modulate Tissue Damage Healing
  • Author : Evanna Huynh
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 212
  • ISBN : 0128143207
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Summary : Mucosal healing in the gastrointestinal tract relies on coordinated events consisting of intestinal epithelial cell restitution, proliferation and differentiation. Growth factors such as epidermal growth factor (EGF) have an essential role in stimulating cell proliferation and differentiation, and maintaining integrity of the intestine to prevent infections and inflammation (colitis) in ...

Nutraceutical Proteins and Peptides in Health and Disease

Nutraceutical Proteins and Peptides in Health and Disease
  • Author : Yoshinori Mine,Fereidoon Shahidi
  • Publisher : CRC Press
  • Release Date : 2005-09-29
  • Total pages : 688
  • ISBN : 0128143207
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Summary : Reports of the beneficial health effects of some peptides have begun to make their way into the scientific literature. Peptides can act as immunomodulators, and have been shown to have a positive influence on calcium absorption, and on regulation of serum cholesterol. A number of peptides may also possess antimicrobial ...

Role of Antimicrobial Peptides in Companion Animal Health

Role of Antimicrobial Peptides in Companion Animal Health
  • Author : Brian Callan Leonard
  • Publisher : Unknown
  • Release Date : 2012
  • Total pages : 212
  • ISBN : 0128143207
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Summary : Antimicrobial peptides (AMPs) are key effector molecules of innate immunity found in a wide array of species ranging from invertebrates to mammals. They are expressed by epithelial cells and leukocytes, and have broad-spectrum antimicrobial activity against many pathogens including bacteria, fungi and some parasites. Two major classes of AMPs in ...

Diet immunity and inflammation

Diet  immunity and inflammation
  • Author : P.J. Moughan,K. Rutherfurd-Markwick
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-09-30
  • Total pages : 760
  • ISBN : 0128143207
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Summary : In addition to supplying essential nutrients, it is now well accepted that some food proteins can confer additional health benefits beyond nutrition. Some food proteins act directly in their intact form to elicit physiological effects, but generally peptides resulting from digestion, hydrolysis or fermentation of the protein are considered of ...

Advances in The Immunology of Host Defense Peptide Mechanisms and Applications of Antimicrobial Functions and Beyond

Advances in The Immunology of Host Defense Peptide  Mechanisms and Applications of Antimicrobial Functions and Beyond
  • Author : Mark Hulett,Charles Lee Bevins,Thanh Kha Phan
  • Publisher : Frontiers Media SA
  • Release Date : 2021-04-07
  • Total pages : 212
  • ISBN : 0128143207
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Summary : Download or read online Advances in The Immunology of Host Defense Peptide Mechanisms and Applications of Antimicrobial Functions and Beyond written by Mark Hulett,Charles Lee Bevins,Thanh Kha Phan, published by Frontiers Media SA which was released on 2021-04-07. Get Advances in The Immunology of Host Defense Peptide ...

Mammalian Host Defense Peptides

Mammalian Host Defense Peptides
  • Author : Deirdre A. Devine,Robert E. W. Hancock
  • Publisher : Cambridge University Press
  • Release Date : 2004-09-20
  • Total pages : 393
  • ISBN : 0128143207
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Summary : Cationic antimicrobial peptides are multifunctional peptides of the innate immune system, which not only act directly against microorganisms, but also signal between early and late immune responses and modulate inflammatory reposnes. The significance of these host defence peptides in combating infection and in host-microbe homeostasis has become increasingly clear, through ...

Walker s Pediatric Gastrointestinal Disease

Walker s Pediatric Gastrointestinal Disease
  • Author : Ronald E. Kleinman,Olivier-Jean Goulet,Giorgina Mieli-Vergani,Ian R. Sanderson,Philip M. Sherman,Benjamin L. Shneider
  • Publisher : PMPH USA, Ltd
  • Release Date : 2018-06-04
  • Total pages : 2368
  • ISBN : 0128143207
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Summary : Download or read online Walker s Pediatric Gastrointestinal Disease written by Ronald E. Kleinman,Olivier-Jean Goulet,Giorgina Mieli-Vergani,Ian R. Sanderson,Philip M. Sherman,Benjamin L. Shneider, published by PMPH USA, Ltd which was released on 2018-06-04. Get Walker s Pediatric Gastrointestinal Disease Books now! Available in PDF, ePub ...

Mechanisms of Epithelial Defense

Mechanisms of Epithelial Defense
  • Author : Dieter Kabelitz,Jens-Michael Schröder
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2005-01-01
  • Total pages : 189
  • ISBN : 0128143207
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Summary : Annotation Epithelial defense against infectious agents relies on the recognition of microbial products by pattern recognition receptors and the local production of antimicrobial peptides. This book provides a state-of-the-art overview of the basic characteristics and clinical relevance of antimicrobial peptides, with special emphasis on their role in skin, intestinal and ...

Studies on Small Intestinal alpha defensin Expression and Function

Studies on Small Intestinal  alpha  defensin Expression and Function
  • Author : Patricia A. Castillo
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 212
  • ISBN : 0128143207
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Summary : Intestinal epithelial cells provide a protective barrier from resident commensal microbes that reside in the lumen, as well as from pathogens that often contaminate ingested food or water. In the small intestine, Paneth cells are an epithelial cell lineage residing in the crypts of Lieberkühn that produce and store ...

Peptide Drug Discovery and Development

Peptide Drug Discovery and Development
  • Author : Miguel Castanho,Nuno Santos
  • Publisher : John Wiley & Sons
  • Release Date : 2011-10-24
  • Total pages : 390
  • ISBN : 0128143207
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Summary : Filling a real knowledge gap, this handbook and ready reference is both modern and forward-looking in its emphasis on the "bench to bedside" translational approach to drug development. Clearly structured into three major parts, the book stakes out the boundaries of peptide drug development in the preclinical as well as ...