Animal Models in Cancer Drug Discovery

Written By Asfar Azmi
Animal Models in Cancer Drug Discovery
  • Publsiher : Academic Press
  • Release : 16 April 2019
  • ISBN : 0128147059
  • Pages : 470 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled Animal Models in Cancer Drug Discovery written by Asfar Azmi which was release on 16 April 2019, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on how these newer models could de-risk modern drug discovery. Areas covered include up to date information on latest organoid derived models and newer genetic models. Additionally, the book discusses humanized animal tumor models for cancer immunotherapy and how they leverage personalized therapies. The chapter on larger animal, canine models and their use in and their use in pre-investigational new drug (pre-IND) development makes the volume unique. Unlike before, the incorporation of several simplified protocols, breeding methodologies, handling and assessment procedures to study drug intervention makes this book a must read. Animal Models in Cancer Drug Discovery is a valuable resource for basic and translational cancer researchers, drug discovery researchers, contract research organizations, and knowledge seekers at all levels in the biomedical field. Encompasses discussions on innovative animal models, xenograft, genetic models, primary models, organoid systems, humanized and other models in modern biology paradigms that are enhancing research in the field of drug discover Covers the use of these models in personalized medicine, immunotherapy, toxicology, pre-IND assessments and related drug development arenas Presents protocols, procedures, and a comprehensive glossary to help new readers understand technical terms and specialized nomenclature

Animal Models in Cancer Drug Discovery

Animal Models in Cancer Drug Discovery
  • Author : Asfar Azmi,Ramzi M. Mohammad
  • Publisher : Academic Press
  • Release Date : 2019-04-16
  • Total pages : 470
  • ISBN : 0128147059
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Summary : Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on ...

Animal Models for Human Cancer Volume 69

Animal Models for Human Cancer  Volume 69
  • Author : Marianne I. Martic-Kehl,Pius August Schubiger,Raimund Mannhold,Hugo Kubinyi,Gerd Folkers
  • Publisher : John Wiley & Sons
  • Release Date : 2016-08-15
  • Total pages : 272
  • ISBN : 0128147059
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Summary : Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for cancer therapies, addressing the widely recognized lack of reliable and reproducible results. Following a short historical introduction and a discussion of the ethics surrounding animal experiments, the ...

Translational Animal Models in Drug Discovery and Development

Translational Animal Models in Drug Discovery and Development
  • Author : Xinkang Wang
  • Publisher : Bentham Science Publishers
  • Release Date : 2012-10-03
  • Total pages : 287
  • ISBN : 0128147059
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Summary : Animal models of diseases play a pivotal role in drug discovery and development, not only for proof of the concept studies of efficacy, PK/PD relationship but also for drug safety assessment. Since considerable differences in variables exist between animal models and human models (such as genetics, physiology, anatomy, gene ...

Relevance of Tumor Models for Anticancer Drug Development

Relevance of Tumor Models for Anticancer Drug Development
  • Author : H. H. Fiebig,A. M. Burger
  • Publisher : S Karger Ag
  • Release Date : 1999
  • Total pages : 462
  • ISBN : 0128147059
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Summary : In recent years, large-scale 'disease-oriented' and 'target-oriented' screening procedures have transformed anticancer drug discovery. As a result several novel therapeutic agents and strategies, aimed to combat cancer via a molecular approach, are being evaluated for their possible clinical benefit. The main topics of this volume address the challenges for current ...

In vivo Models for Drug Discovery

In vivo Models for Drug Discovery
  • Author : José Miguel Vela,Rafael Maldonado,Michel Hamon
  • Publisher : John Wiley & Sons
  • Release Date : 2014-08-11
  • Total pages : 594
  • ISBN : 0128147059
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Summary : This one-stop reference is the first to present the complete picture -- covering all relevant organisms, from single cells to mammals, as well as all major disease areas, including neurological disorders, cancer and infectious diseases. Addressing the needs of the pharmaceutical industry, this unique handbook adopts a broad perspective on ...

GEN Guide to Biotechnology Companies

GEN Guide to Biotechnology Companies
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1997
  • Total pages : 212
  • ISBN : 0128147059
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Summary : Download or read online GEN Guide to Biotechnology Companies written by , published by which was released on 1997. Get GEN Guide to Biotechnology Companies Books now! Available in PDF, ePub and Kindle....

Drug Discovery Handbook

Drug Discovery Handbook
  • Author : Shayne Cox Gad
  • Publisher : John Wiley & Sons
  • Release Date : 2005-07-08
  • Total pages : 1496
  • ISBN : 0128147059
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Summary : The Drug Discovery Handbook gives professionals a tool tofacilitate drug discovery by bringing together, for the first timein one resource, a compendium of methods and techniques that needto be considered when developing new drugs. This comprehensive, practical guide presents an explanation of thelatest techniques and methods in drug discovery, including: ...

Cancer Research

Cancer Research
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 212
  • ISBN : 0128147059
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Summary : Download or read online Cancer Research written by , published by which was released on 2008. Get Cancer Research Books now! Available in PDF, ePub and Kindle....

Directory of Research Grants 2002

Directory of Research Grants 2002
  • Author : Grants Program,Oryx Publishing
  • Publisher : Greenwood
  • Release Date : 2002
  • Total pages : 908
  • ISBN : 0128147059
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Summary : More than 5,100 current programs from 1,880 sponsors, including U.S. and foreign foundations, corporations, government agencies, and other organizations....

Journal of the National Cancer Institute

Journal of the National Cancer Institute
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2004
  • Total pages : 212
  • ISBN : 0128147059
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Summary : "Summaries of papers" contained in the journal accompany each issue, 19--...

Science Culture

Science   Culture
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2004
  • Total pages : 212
  • ISBN : 0128147059
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Summary : Download or read online Science Culture written by , published by which was released on 2004. Get Science Culture Books now! Available in PDF, ePub and Kindle....

Science

Science
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2002
  • Total pages : 212
  • ISBN : 0128147059
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Summary : Download or read online Science written by , published by which was released on 2002. Get Science Books now! Available in PDF, ePub and Kindle....

Drug Screening Methods

Drug Screening Methods
  • Author : S. K. Gupta
  • Publisher : Anshan Pub
  • Release Date : 2005
  • Total pages : 501
  • ISBN : 0128147059
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Summary : Drug discovery and development is a challenging, expensive and time consuming field of research, requiring contributions from chemists, pharmacologists, toxicologists, clinicians, and practitioners. The ultimate goal is to generate a safe and biologically active drug which can stall, or even reverse, the pathological events that cause the disease condition. But ...

Transgenic Animal Models

Transgenic Animal Models
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2003
  • Total pages : 146
  • ISBN : 0128147059
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Summary : Download or read online Transgenic Animal Models written by , published by which was released on 2003. Get Transgenic Animal Models Books now! Available in PDF, ePub and Kindle....

American Book Publishing Record

American Book Publishing Record
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2003
  • Total pages : 212
  • ISBN : 0128147059
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Summary : Download or read online American Book Publishing Record written by , published by which was released on 2003. Get American Book Publishing Record Books now! Available in PDF, ePub and Kindle....