A Practical Guide to Rational Drug Design

Written By Sun Hongmao
A Practical Guide to Rational Drug Design
  • Publsiher : Woodhead Publishing
  • Release : 01 October 2015
  • ISBN : 9780081000984
  • Pages : 292 pages
  • Rating : 4/5 from 21 reviews
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Read or download book entitled A Practical Guide to Rational Drug Design written by Sun Hongmao which was release on 01 October 2015, this book published by Woodhead Publishing. Available in PDF, EPUB and Kindle Format. Book excerpt: This book is not going to be an exhaustive survey covering all aspects of rational drug design. Instead, it is going to provide critical know-how through real-world examples. Relevant case studies will be presented and analyzed to illustrate the following: how to optimize a lead compound whether one has high or low levels of structural information; how to derive hits from competitors' active compounds or from natural ligands of the targets; how to springboard from competitors' SAR knowledge in lead optimization; how to design a ligand to interfere with protein-protein interactions by correctly examining the PPI interface; how to circumvent IP blockage using data mining; how to construct and fully utilize a knowledge-based molecular descriptor system; how to build a reliable QSAR model by focusing on data quality and proper selection of molecular descriptors and statistical approaches. A Practical Guide to Rational Drug Design focuses on computational drug design, with only basic coverage of biology and chemistry issues, such as assay design, target validation and synthetic routes. Discusses various tactics applicable to daily drug design Readers can download the materials used in the book, including structures, scripts, raw data, protocols, and codes, making this book suitable resource for short courses or workshops Offers a unique viewpoint on drug discovery research due to the author's cross-discipline education background Explores the author's rich experiences in both pharmaceutical and academic settings

A Practical Guide to Rational Drug Design

A Practical Guide to Rational Drug Design
  • Author : Sun Hongmao
  • Publisher : Woodhead Publishing
  • Release Date : 2015-10-01
  • Total pages : 292
  • ISBN : 9780081000984
GET BOOK

Summary : This book is not going to be an exhaustive survey covering all aspects of rational drug design. Instead, it is going to provide critical know-how through real-world examples. Relevant case studies will be presented and analyzed to illustrate the following: how to optimize a lead compound whether one has high ...

Rational Drug Design

Rational Drug Design
  • Author : American Chemical Society,Abby L. Parrill,M. Rami Reddy,American Chemical Society. Division of Computers in Chemistry
  • Publisher : Amer Chemical Society
  • Release Date : 1999
  • Total pages : 374
  • ISBN : 9780081000984
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Summary : This book provides both an overview of current progress in the field of rational drug design and an update on activites related to applied drug design and the development of new methodology for drug design....

A Practical Guide to Rational Drug Design

A Practical Guide to Rational Drug Design
  • Author : Sun Hongmao
  • Publisher : Woodhead Publishing
  • Release Date : 2015-10-05
  • Total pages : 292
  • ISBN : 9780081000984
GET BOOK

Summary : This book is not going to be an exhaustive survey covering all aspects of rational drug design. Instead, it is going to provide critical know-how through real-world examples. Relevant case studies will be presented and analyzed to illustrate the following: how to optimize a lead compound whether one has high ...

Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design

Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design
  • Author : Sanjeev Kumar Singh
  • Publisher : Springer Nature
  • Release Date : 2021-06-16
  • Total pages : 212
  • ISBN : 9780081000984
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Summary : Download or read online Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design written by Sanjeev Kumar Singh, published by Springer Nature which was released on . Get Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design Books now! Available in PDF, ePub ...

A Practical Guide to Combinatorial Chemistry

A Practical Guide to Combinatorial Chemistry
  • Author : Anthony W. Czarnik,Sheila Hobbs Dewitt
  • Publisher : Amer Chemical Society
  • Release Date : 1997
  • Total pages : 450
  • ISBN : 9780081000984
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Summary : Combinatorial chemistry is the ability to simultaneously synthesize vast numbers of diverse compounds. Its techniques have revolutionized the drug discovery process, and are widely used throughout the biotechnology community. Aimed at a wide audience, this text is a down-to-earth introductionto small molecule combinatorial chemistry. It uses a tutorial approach to ...

New Perspectives in Drug Design

New Perspectives in Drug Design
  • Author : P. M. Dean,Philip Michael Dean,Georges Jolles,C. G. Newton
  • Publisher : Unknown
  • Release Date : 1995
  • Total pages : 321
  • ISBN : 9780081000984
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Summary : This text updates the first Rhone-Poulenc Rorer Round Table Conference volume on the subject of drug design. It covers topics from the practicalities of synthetic organic chemistry to the potential pitfalls in the mathematics of free-energy calculations....

Anticancer Research

Anticancer Research
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1997
  • Total pages : 212
  • ISBN : 9780081000984
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Summary : Download or read online Anticancer Research written by , published by which was released on 1997. Get Anticancer Research Books now! Available in PDF, ePub and Kindle....

Bibliography of Agriculture

Bibliography of Agriculture
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1993
  • Total pages : 212
  • ISBN : 9780081000984
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Summary : Download or read online Bibliography of Agriculture written by , published by which was released on 1993. Get Bibliography of Agriculture Books now! Available in PDF, ePub and Kindle....

The Edition XII Guide to Postgraduate Arts Humanities and Social Sciences Programmes in Europe 1995

The Edition XII Guide to Postgraduate Arts  Humanities and Social Sciences Programmes in Europe  1995
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1995
  • Total pages : 400
  • ISBN : 9780081000984
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Summary : Download or read online The Edition XII Guide to Postgraduate Arts Humanities and Social Sciences Programmes in Europe 1995 written by , published by which was released on 1995. Get The Edition XII Guide to Postgraduate Arts Humanities and Social Sciences Programmes in Europe 1995 Books now! Available in PDF, ePub and Kindle....

Designing Bioactive Molecules

Designing Bioactive Molecules
  • Author : Yvonne Connolly Martin,Peter Willett
  • Publisher : Amer Chemical Society
  • Release Date : 1998
  • Total pages : 276
  • ISBN : 9780081000984
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Summary : Three-dimensional structural information often provides the key to dis covering or designing bioactive molecules and compounds. This volume c overs the principal computational techniques for processing three-dime nsional structures of small molecules and compounds. It describes data base construction and searching, analysis of structure-activity relati onships by pharmacophore mapping and ...

International Books in Print

International Books in Print
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1994
  • Total pages : 212
  • ISBN : 9780081000984
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Summary : Download or read online International Books in Print written by , published by which was released on 1994. Get International Books in Print Books now! Available in PDF, ePub and Kindle....

The British National Bibliography

The British National Bibliography
  • Author : Arthur James Wells
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 212
  • ISBN : 9780081000984
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Summary : Download or read online The British National Bibliography written by Arthur James Wells, published by which was released on 2009. Get The British National Bibliography Books now! Available in PDF, ePub and Kindle....

Advances in Drug Discovery Techniques

Advances in Drug Discovery Techniques
  • Author : Alan L. Harvey
  • Publisher : John Wiley & Sons
  • Release Date : 1998-08-17
  • Total pages : 224
  • ISBN : 9780081000984
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Summary : This invaluable volume serves as a guide to up-to-the-minute techniques for the discovery and evaluation of pharmacologically active compounds for therapeutic development. Focusing on practical applications, provided by expert practitioners from both industry and academic research laboratories, Advances in Drug Discovery Techniques covers rational drug design, high-throughput screening and genetic ...

DttP

DttP
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2001
  • Total pages : 212
  • ISBN : 9780081000984
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Summary : Download or read online DttP written by , published by which was released on 2001. Get DttP Books now! Available in PDF, ePub and Kindle....

American Book Publishing Record

American Book Publishing Record
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1998
  • Total pages : 212
  • ISBN : 9780081000984
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Summary : Download or read online American Book Publishing Record written by , published by which was released on 1998. Get American Book Publishing Record Books now! Available in PDF, ePub and Kindle....