A Comprehensive Guide to Toxicology in Nonclinical Drug Development

Written By Ali S. Faqi
A Comprehensive Guide to Toxicology in Nonclinical Drug Development
  • Publsiher : Academic Press
  • Release : 03 November 2016
  • ISBN : 0128036214
  • Pages : 986 pages
  • Rating : 4/5 from 21 reviews
GET THIS BOOKA Comprehensive Guide to Toxicology in Nonclinical Drug Development


Read or download book entitled A Comprehensive Guide to Toxicology in Nonclinical Drug Development written by Ali S. Faqi which was release on 03 November 2016, this book published by Academic Press. Available in PDF, EPUB and Kindle Format. Book excerpt: A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more. Thoroughly updated to reflect the latest scientific advances and with increased coverage of international regulatory guidelines, this second edition is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides unique content that is not always covered together in one comprehensive resource, including chapters on stem cells, abuse liability, biomarkers, inhalation toxicology, biostatistics, and more Updated with the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and the expectations associated with working in nonclinical toxicology

A Comprehensive Guide to Toxicology in Nonclinical Drug Development

A Comprehensive Guide to Toxicology in Nonclinical Drug Development
  • Author : Ali S. Faqi
  • Publisher : Academic Press
  • Release Date : 2016-11-03
  • Total pages : 986
  • ISBN : 0128036214
GET BOOK

Summary : A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem ...

A Comprehensive Guide to Toxicology in Preclinical Drug Development

A Comprehensive Guide to Toxicology in Preclinical Drug Development
  • Author : Ali S. Faqi
  • Publisher : Academic Press
  • Release Date : 2012-11-16
  • Total pages : 885
  • ISBN : 0128036214
GET BOOK

Summary : A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide ...

Current Topics in Nonclinical Drug Development

Current Topics in Nonclinical Drug Development
  • Author : Pritam S. Sahota,Philip Bentley,Zbigniew Wojcinski
  • Publisher : CRC Press
  • Release Date : 2020-12-23
  • Total pages : 318
  • ISBN : 0128036214
GET BOOK

Summary : The inaugural volume in the Current Topics in Nonclinical Drug Development Series explores the critical issues and current topics in nonclinical drug development. This first volume covers individual topics and strategies in drug development from compound characterization to drug registration. Written by a variety of experts in the field, recent ...

Essentials of Laboratory Animal Science Principles and Practices

Essentials of Laboratory Animal Science  Principles and Practices
  • Author : P. Nagarajan,Ramachandra Gudde,Ramesh Srinivasan
  • Publisher : Springer Nature
  • Release Date : 2021-08-24
  • Total pages : 806
  • ISBN : 0128036214
GET BOOK

Summary : This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used ...

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment
  • Author : Joerg Bluemel,Sven Korte,Emanuel Schenck,Gerhard Weinbauer
  • Publisher : Academic Press
  • Release Date : 2015-03-13
  • Total pages : 716
  • ISBN : 0128036214
GET BOOK

Summary : The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, ...

Botanical Drug Products

Botanical Drug Products
  • Author : Jayant N. Lokhande,Yashwant V. Pathak
  • Publisher : CRC Press
  • Release Date : 2018-11-21
  • Total pages : 274
  • ISBN : 0128036214
GET BOOK

Summary : Botanicals, which have been part of human food and medicine for thousands of years, are perceived as being safer than synthetic pharmaceuticals. The global botanical drug market was expected to reach $26.6 billion by 2017. In terms of FDA regulations, botanical drugs are no different from non-botanical products, having to meet the ...

Drug Discovery and Development Third Edition

Drug Discovery and Development  Third Edition
  • Author : James J. O'Donnell,John Somberg,Vincent Idemyor,James T. O'Donnell
  • Publisher : CRC Press
  • Release Date : 2019-12-13
  • Total pages : 668
  • ISBN : 0128036214
GET BOOK

Summary : Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and evaluation of ...

Drug Safety in Developing Countries

Drug Safety in Developing Countries
  • Author : Yaser Mohammed Al-Worafi
  • Publisher : Academic Press
  • Release Date : 2020-06-03
  • Total pages : 686
  • ISBN : 0128036214
GET BOOK

Summary : Drug Safety in Developing Countries: Achievements and Challenges provides comprehensive information on drug safety issues in developing countries. Drug safety practice in developing countries varies substantially from country to country. This can lead to a rise in adverse reactions and a lack of reporting can exasperate the situation and lead ...

Preclinical Development Handbook

Preclinical Development Handbook
  • Author : Shayne Cox Gad
  • Publisher : John Wiley & Sons
  • Release Date : 2008-03-21
  • Total pages : 1080
  • ISBN : 0128036214
GET BOOK

Summary : A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic,comprehensive reference to prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. This single definitive, easy-to-use ...

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment
  • Author : Joerg Bluemel,Sven Korte,Emanuel Schenck,Gerhard F. Weinbauer
  • Publisher : Academic Press
  • Release Date : 2015-03-12
  • Total pages : 716
  • ISBN : 0128036214
GET BOOK

Summary : Annotation This reference compiles the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, safety assessment of biologics and small molecules, immunotoxicology and much more, it ...

Antibody Drug Conjugates

Antibody Drug Conjugates
  • Author : Kenneth J. Olivier, Jr.,Sara A. Hurvitz
  • Publisher : John Wiley & Sons
  • Release Date : 2016-11-14
  • Total pages : 560
  • ISBN : 0128036214
GET BOOK

Summary : Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells. • Discusses the basics, drug delivery strategies, pharmacology and toxicology, and regulatory approval strategies • Covers the conduct and design ...

Development and Approval of Combination Products

Development and Approval of Combination Products
  • Author : Evan B. Siegel
  • Publisher : John Wiley & Sons
  • Release Date : 2008-06-09
  • Total pages : 216
  • ISBN : 0128036214
GET BOOK

Summary : A step-by-step, integrated approach for successful, FDA-approved combination drug products Using a proven integrated approach to combination drug development, this book guides you step by step through all the preclinical, clinical, and manufacturing stages. Written from an FDA regulatory perspective, the book not only enables you to bring a successful ...

Drug Safety Evaluation

Drug Safety Evaluation
  • Author : Shayne Cox Gad
  • Publisher : John Wiley & Sons
  • Release Date : 2016-12-01
  • Total pages : 918
  • ISBN : 0128036214
GET BOOK

Summary : This practical guide presents a road map for safety assessment as an integral part of the development of new drugs and therapeutics. Helps readers solve scientific, technical, and regulatory issues in preclinical safety assessment and early clinical drug development Explains scientific and philosophical bases for evaluation of specific concerns – including ...

Accelerated Path to Cures

Accelerated Path to Cures
  • Author : Josep Bassaganya-Riera
  • Publisher : Springer
  • Release Date : 2018-04-25
  • Total pages : 82
  • ISBN : 0128036214
GET BOOK

Summary : Accelerated Path to Cures provides a transformative perspective on the power of combining advanced computational technologies, modeling, bioinformatics and machine learning approaches with nonclinical and clinical experimentation to accelerate drug development. This book discusses the application of advanced modeling technologies, from target identification and validation to nonclinical studies in animals ...

Developmental and Reproductive Toxicology

Developmental and Reproductive Toxicology
  • Author : Ronald D Hood
  • Publisher : CRC Press
  • Release Date : 2011-12-14
  • Total pages : 856
  • ISBN : 0128036214
GET BOOK

Summary : The purpose of this third edition of Developmental and Reproductive Toxicology is to provide a practical guide to developmental and reproductive toxicology in a regulatory environment. In addition to a comprehensive update of current chapters, the third edition been revised to reflect recent changes in the field. It contains new ...